Journals / Haydarpaşa Numune Eğitim ve Araştırma Hastanesi Tıp Dergisi / 2005 / Cilt: 45 - Sayı: 3

Ventile yenidoğanlarda sepsis etkeninin belirlenmesinde endotrakeal kültürleri

Endotracheal aspirate cultures in predicting sepsis in ventilated newborns

Pages
129–132
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Moreover, resistant organisms may occur in hospitals by the antibiotics used unnecessarily.

📌 3 Key Takeaways

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Objective & Hypothesis:Newborns are the most vulnerable age group for nozocomial infections.
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Key Findings & Data:As the rates of nozocomial infections increase with invasive methods, ventilated babies have the higher risk.
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Conclusion & Impact:Moreover, resistant organisms may occur in hospitals by the antibiotics used unnecessarily.
🔬Design:Research Article
📍Scope:2001 Verileri
⚙️Variables:Domain Parameters

Abstract

Newborns are the most vulnerable age group for nozocomial infections. As the rates of nozocomial infections increase with invasive methods, ventilated babies have the higher risk. Intubation associated lesions of the pharynx and the trachea leads to bacterial colonization by the deterioration of the swallowing reflex and the ciliary functions. Objective: To show the value of serial endotracheal aspirate culture in predicting organisms causing sepsis in ventilated neonates. Materials and Methods: The study was performed among 100 newborns in Zeynep Kamil Maternity and Children's Education and Research Hospital, Neonatal Intensive Care Unit between June 2001 and June 2002. Endotracheal aspirate and blood cultures were taken on the third day firstly and then once a week till extubation simultaneously. Results: Results of the blood and endotracheal cultures showed the same organism only in 17.6% of the patient. We determined that the rate of culture positivity increased while the birth weight decreased, gestation week got smaller and the duration of intubation prolonged. Conclusion: The antibiotherapy arranged according to the endotracheal aspirate cultures is not suitable for a possible sepsis agent. Moreover, resistant organisms may occur in hospitals by the antibiotics used unnecessarily.

Özet

Ventile Yenidoğanlarda Sepsis Etkeninin Belirlenmesinde Endotrakeal Aspirat Kültürleri Yenidoğanlar, nazokomial enfeksiyonlara en duyarlı yaş grubudur, invazif girişim uygulanması ile nazokomial enfeksiyon riski de arttığından, ventile edilen bebeklerde risk yüksektir. Entübasyona bağlı lezyonlar, yutma refleksi ve siliyer fonksiyonlarda bozulmaya yol açarak farenks ve trakeada bakteriyel kolonizasyona neden olurlar. Amaç: Ventile yenidoğanlarda gelişebilecek sepsis etkenini belirlemede seri endotrakeal aspirat kültürlerinin değerini göstermek amaçlanmıştır. Gereç ve Yöntem: Çalışma, 1 yıllık süre boyunca (Haziran 2001-Haziran 2002) Zeynep Kamil Kadın ve Çocuk Hastalıkları Eğitim ve Araştırma Hastanesi, Yenidoğan Yoğun Bakım Ünitesi'nde tedavi gören 100 bebekte gerçekleştirilmiştir. Endotrakeal aspirat ve kan kültürleri, ilk olarak 3. gün ve sonrasında da haftada bir olacak şekilde eşzamanlı olarak alınmıştır. Bulgular: Hastaların sadece %17.6'sında kan ve endotrakeal aspirat kültüründe aynı mikroorganizma üremiştir. Doğum ağırlığı azaldıkça, gestasyon haftası küçüldükçe ve entübasyon süresi arttıkça, kültürlerde üreme oranının arttığı gözlenmiştir. Tartışma: Endotrakeal aspirat kültür sonucuna göre antibiyotik tedavisi düzenlemek, oluşabilecek bir sepsis tedavisi için uygun olmayacaktır. Daha da önemlisi, gereksiz antibiyotik kullanımı ile hastanelerde rezistan mikroorganizmalarda artış olabilir.

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Cite This Article

İPEK, O. İ., BOZAYKUT, A., ATAY, E., KILIÇ, D. B. (2022). Ventile yenidoğanlarda sepsis etkeninin belirlenmesinde endotrakeal kültürleri. Haydarpaşa Numune Eğitim ve Araştırma Hastanesi Tıp Dergisi, Cilt: 45 - Sayı: 3, 129–132. https://ajindex.com/articles/535630

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