SavedAdd your journal

Journals / Haydarpaşa Numune Eğitim ve Araştırma Hastanesi Tıp Dergisi / 2005 / Cilt: 45 - Sayı: 2

Myasthenia gravis and anaesthesia (A case report)

Miyastenia gravis ve anestezi (Olgu sunumu)

Zuhal ARIKAN
Hakan ERKAL
Erhan ÇIPLAKLIĞİL
Yaman ÖZYURT
Yasin YENER
Pages
110–112
Publication Date
2022-10-17
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The purpose of this case report is to review the anest­hetic management of a patient with myasthenia gravis.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Myasthenia gravis is a neurological autoimmune disease which has great significance for the anaesthesiologists.
📊
Key Findings & Data:Muscle weakness and fatigabi-lity arise from defective or decreased acetylcholine receptors at the neuromuscular junctions.
💡
Conclusion & Impact:The purpose of this case report is to review the anest­hetic management of a patient with myasthenia gravis.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Myasthenia gravis is a neurological autoimmune disease which has great significance for the anaesthesiologists. It is characterized by muscle weakness that worsens on repetiti­on but improves with resting. Muscle weakness and fatigabi-lity arise from defective or decreased acetylcholine receptors at the neuromuscular junctions. The most prevalent cause of myasthenia gravis is an autoimmune disorder in which the patient produces antibodies that attach the nicotinic acetylc­holine receptor at the neuromuscular junction. The purpose of this case report is to review the anest­hetic management of a patient with myasthenia gravis.

Özet

Miyastenia gravis, anestezistleri büyük oranda ilgilen­diren, otoimmün, nörolojik bir hastalıktır. Tekrarlamakla artan, ancak dinlenme ile düzelen kas güçsüzlüğü ile ka-rakterizedir. Sinir kas kavşağındaki asetilkolin reseptörle-rindeki fonksiyon bozukluğu veya sayıca azalma sonucu kas güçsüzlüğü ve yorgunluk ortaya çıkar. Miyastenia gravisin ortaya çıkmasındaki en önemli nedenin, sinir kas kavşağındaki nikotinik asetilkolin reseptörlerine karşı has­ta tarafından geliştirilen antikorlar olduğu düşünülmekte­dir. Bu olgu sunumunun amacı, miyastenia gravisli bir hastada anestezik yaklaşımı gözden geçirmektir.

🔖

Cite This Article

ARIKAN, Z., ERKAL, H., ÇIPLAKLIĞİL, E., ÖZYURT, Y., YENER, Y. (2022). Myasthenia gravis and anaesthesia (A case report). Haydarpaşa Numune Eğitim ve Araştırma Hastanesi Tıp Dergisi, Cilt: 45 - Sayı: 2, 110–112. https://ajindex.com/articles/535624

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (12)

  1. Drachman DB, Adams RN, Josifek LF et al. Functional ac­tivities of autoantibodies to acetylcholine receptors and the clinical severity of myasthenia gravis. N Engl J Med 1982;307:769
  2. Basaranoglu G, Erden V, Delatioglu H. Anesthesia of a pa­tient with cured myasthenia gravis. Anesth Analg 2003;96(6):1842
  3. Gardner SV, Evans NR. The ProSeal laryngeal mask in myasthenia gravis. Anesth Intensive Care 2002;30(5):671
  4. Abel M, Eisenkraft JB. Anesthetic implications of myasthe­ nia gravis. Mt Sinai J Med 2002;69(1-2):31
  5. Book JW. Anesthesia and neuromuscular diseases. Anestesiology Clinics of North America 1996;14:515
  6. Ceremuga TE, Yao XL, Me Cabe JT. Etiology, mechanisms and anesthesia implications of autoimmune myasthenia gravis. AANA J 2002;70(4):301
  7. Richman DP, Agius MA. Treatment of autoimmune myast­ henia gravis. Neurology 2003;23-61(12):1652
  8. Krucylak PE, Naunheim KS. Preoperative preparation and anesthetic management of patients with myasthenia gravis. Semin Thorac Cardiovasc Surg 1999;11(1):47
  9. Morgan GE, Mikhail MS, Murray MJ. Anesthesia for pati­ents with neuromuscular disease. Clinical Anesthesiology. Third edition. New York, Me Graw-Hill. 2002;752-60
  10. Delia Rocca G, Coccia C, Diana L et al. Propofol or sevoflurane anesthesia without muscle reiaxants allow the early extubation of myasthenic patients. Can J Anesth 2003;50 (6): 547
  11. Kiran U, Choudhury M, Saxena N, Kapoor P. Sevoflurane as a sole anesthetic for thymectomy in myasthenia gravis. Acta Anaesthesiol Scand 2000;44(3):351
  12. Leventhal SR, Orkin FK, Hirsh RA. Prediction of the need for postoperative mechanical ventilation in myasthenia gravis. Anesthesiology 1980;53:26.