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Journals / Haydarpaşa Numune Eğitim ve Araştırma Hastanesi Tıp Dergisi / 2007 / Cilt: 47 - Sayı: 2

Is normoblast in peripheral blood smear of newborn a good marker of anoxia?

Yenidoğan periferik yaymasında normoblast: İyi bir anoksi göstergesi midir?

Kenan BARUT
Serap KARAMAN
Barbaros ILIKKAN
Tiraje CELKAN
Pages
331–334
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Here we present a 33 week gestational age-SGA baby, born to preeclamptic mother in order to discuss the detection of increase in normoblast on peripheral smear, as a marker of perinatal asphyxia.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Perinatal asphyxia is one of the most important reason for children mortality and morbidity in the world.
📊
Key Findings & Data:Its incidence is around 1 -5 % depending on the gestatio-nal age and birthweight.
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Conclusion & Impact:Here we present a 33 week gestational age-SGA baby, born to preeclamptic mother in order to discuss the detection of increase in normoblast on peripheral smear, as a marker of perinatal asphyxia.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Perinatal asphyxia is one of the most important reason for children mortality and morbidity in the world. Its incidence is around 1 -5 % depending on the gestatio-nal age and birthweight. Risk factors for perinatal asphyxia can be related with fetus, mother, gestation and birth. APGAR score, acid-base analysis of umblilical cord blood and fetal scalp, pH measurement are some of the parameters which can show perinatal asphyxia. However there is not a single excellent marker of perinatal asphyxia. Recently there are researches which suggest that ratio of normoblast / 100 leukocytes could be used as a marker of perinatal asphyxia in the newborn. Here we present a 33 week gestational age-SGA baby, born to preeclamptic mother in order to discuss the detection of increase in normoblast on peripheral smear, as a marker of perinatal asphyxia.

Özet

Perinatal asfiksi, tüm dünyada perinatal mortalite ve morbiditenin en önemli sebeplerindendir. İnsidans, genellikle gebelik yaşı ve doğum ağırlığı ile ilişkili olup %1-5 oranında değişmektedir. Perinatal asfiksiye yol açabilen riskli durumlar fetusla, anneyle, gebelik ya da doğumla ilgili olabilir (1). Perinatal asfiksinin göstergesi olarak apgar skoru, umblikal örnekten alınan kan ör-neğindaki asit-baz analizleri, fetal skalptan pH ölçümü gibi parametreler kullanılmaktadır. Ancak hala perinatal asfiksi için iyi bir gösterge olarak kullanılabilecek tek bir marker yoktur. Son zamanlarda yenidoğanda her 100 lökosit başına sayılan normoblast oranının perinatal asfikside bir marker olarak kullanılabileceğini gösteren çalışmalar mevcuttur. Biz de 33 haftalık preterm-SGA (intrauterin gelişme geriliği) olarak preeklamtik anneden sezaryen ile doğurtulan bir yenidoğan olgusunda, periferik yaymada saptadığımız normoblast artışının perinatal asfiksinin bir göstergesi olarak kullanılabileceğini tartışmak amacıyla olguyu sunmak istedik.

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Cite This Article

BARUT, K., KARAMAN, S., ILIKKAN, B., CELKAN, T. (2022). Is normoblast in peripheral blood smear of newborn a good marker of anoxia?. Haydarpaşa Numune Eğitim ve Araştırma Hastanesi Tıp Dergisi, Cilt: 47 - Sayı: 2, 331–334. https://ajindex.com/articles/535598

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