Journals / Haydarpaşa Numune Eğitim ve Araştırma Hastanesi Tıp Dergisi / 2008 / Cilt: 48 - Sayı: 4

Methylenettrahydrofolate reductase polymorphisms in pancreatic cholangiocellular cancer

Pankreas ve kolanjiyoselüler kanserlerinde metilen tetrahidrofolat redüktaz gen polimorfizmi

Pages
208–212
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Results: In the patient group, serum glucose level at 2nd hour, triglyceride and insulin levels, CRP and HOMA- IR were significantly high (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: Hepatosteatosis is frequently seen in middle-aged women who mostly are obese and have insulin resistance.
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Key Findings & Data:Method: Thirthy eight patients and fourteen healthy people aged 30 and over were included in the study.
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Conclusion & Impact:Results: In the patient group, serum glucose level at 2nd hour, triglyceride and insulin levels, CRP and HOMA- IR were significantly high (p
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: Hepatosteatosis is frequently seen in middle-aged women who mostly are obese and have insulin resistance. In this study, we investigated the relationship between hepatosteatosis detected on sonography and insulin resistance in obese women with normal glucose tolerance. Method: Thirthy eight patients and fourteen healthy people aged 30 and over were included in the study. A sonographic examination was performed to diagnose hepatosteatosis. Also, serum fasting glucose level, cholosterol, triglyceride, LDL- cholosterol and HDLcholosterol, insulin and CRP levels checked for the study. The insulin resistance in patients were detected by HOMA-IR method (homeastasis model assessment of insulin resistance). Results: In the patient group, serum glucose level at 2nd hour, triglyceride and insulin levels, CRP and HOMA- IR were significantly high (p

Özet

Amaç: Bu çalışmada, normal glikoz toleranslı obez kadı n hastalarda ultrason ile saptanan karaciğer yağlanması ile insülin direnci arasındaki ilişkinin incelenmesi amaçlandı. Gereç ve Yöntemler: Çalışmaya beden kitle indeksi (BK‹) 30 ve üstü ultrasonografi ile karaciğer yağlanması saptanan 38 kadın hasta ve 14 sağlıklı kontrol alındı. Hastaların açlık kan şekeri, kolesterol, trigliserid, LDLkolesterol, HDL-kolesterol, insülin ve CRP düzeylerine bakıldı. Hastaların insülin direnci HOMA-IR (homeastasis model assement of insülin resistance) metodu ile saptandı. Bulgular: Hasta grubunda 2. saat kan şekeri, trigliserid, insülin, CRP ve HOMA-IR değerleri kontrol grubuna göre anlamlı derecede yüksek (sırasıyla; p

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Cite This Article

AKAY, S., TOPÇUOĞLU, N., AKYILDIZ, M., KOSOVA, B., AYDIN, A., EROĞLU, Z. (2022). Methylenettrahydrofolate reductase polymorphisms in pancreatic cholangiocellular cancer. Haydarpaşa Numune Eğitim ve Araştırma Hastanesi Tıp Dergisi, Cilt: 48 - Sayı: 4, 208–212. https://ajindex.com/articles/535543

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