Journals / Haydarpaşa Numune Eğitim ve Araştırma Hastanesi Tıp Dergisi / 2012 / Cilt: 52 - Sayı: 2

Analysis of the patients who underwent transrectal ultrasound guided prostate biopsy

Transrektal ultrasonografi eşliğinde prostat biyopsisi yapılan hastaların analizi

Pages
83–87
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

PSA levels are higher in PC patients when compared with BPH patients.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: In our study we aimed to determine incidence of prostate cancer (PC) in patients who underwent transrectal ultrasound (TRUS) guided prostate biopsy and the differences between benign prostatic hyperplasia (BPH) and PC in terms of age and PSA levels.
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Key Findings & Data:Materials and Methods: 2175 patients who underwent TRUS guided prostate biopsy between 2004 and 2010 years were studied.
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Conclusion & Impact:PSA levels are higher in PC patients when compared with BPH patients.
🔬Design:Research Article
📍Scope:2004 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: In our study we aimed to determine incidence of prostate cancer (PC) in patients who underwent transrectal ultrasound (TRUS) guided prostate biopsy and the differences between benign prostatic hyperplasia (BPH) and PC in terms of age and PSA levels. Materials and Methods: 2175 patients who underwent TRUS guided prostate biopsy between 2004 and 2010 years were studied. Total PSA, prostate volume (PV) were determined. Patientsages were between 41 and 96 years. Abnormal digital rectal examination and high PSA levels (>4 ng/ml) were the indications of TRUS guided prostate biopsy. Results: PC was diagnosed in 662 patients (%30.4).1403 patients (%64.5) had BPH pathology. High grade prostatic intraepithelial neoplasia (HGPIN) and atypical small acinar proliferation (ASAP) were diagnosed in 13 (%0.6) and 81 (%3.6) patients. Granulomatous prostatitis (GP) was detected in 7 patients (%0.3). Mean ages of BPH and PC patients were 66.2±9.4 and 70.3±8.7. Total PSA levels were 9.5±7.2 ng/ml in BPH patients and 90.2±31.1 ng/ml in PC patients. Conclusions: TRUS guided biopsy is necessary for diagnosis of PC. But approximately one third of the patients who were biopsied have PC. PC is seen in more advanced ages than BPH. PSA levels are higher in PC patients when compared with BPH patients.

Özet

Amaç: Çalışmamızda transrektal ultrasonografi (TRUS) eşliğinde prostat biyopsisi yapılan hastalarda prostat kanseri (PK) insidansını belirlemeyi ve prostat kanseri ile benign prostat hiperplazisi (BPH) arasındaki yaş ve prostat spesifik antijen (PSA) değerleri arasındaki farklılığı tespit etmeyi amaçladık. Gereç ve Yöntem: 2004 ve 2010 yılları arasında TRUS eşliğinde prostat biyopsisi yapılan 2175 hasta çalışmaya alındı. Total PSA, prostat hacmi tespit edildi. Hastaların yaşı 41 ile 96 arasındaydı. Anormal rektal muayene bulgusu varlığı ve yüksek PSA değerleri (>4 ng/ml) TRUS eşliğinde prostat biyopsi endikasyonlarıydı. Sonuç: PK 662 hastada tespit edildi. 1403 hastada BPH patolojisi vardı. Yüksek dereceli intraepitelyal neoplazi ve atipik küçük asiner proliferasyon sırasıyla 13 ve 81 hastada tespit edildi. Granülomatöz prostatit (GP) 7 hastada saptandı. BPH li ve PK li hastaların ortalama yaşı 66.2±9.4 ve 70.3±8.7 idi. Total PSA değerlerin BPH li hastalarda 9.5±7.2 ng/ml iken PK li hastalarda 90.2±31.1 ng/ml idi. Tartışma: PK tanısı için TRUS eşliğinde biyopsi gereklidir. Fakat yaklaşık olarak biyopsi yapılan hastaların üçte biri prostat kanseridir. PK BPH ne gore daha ileri yaşlarda görülür. PSA değerleri PK li hastalarda daha yüksektir.

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Cite This Article

ÇALIŞKAN, S., KAHRAMAN, M. İ., AKYÜZ, M., KOCA, O. (2022). Analysis of the patients who underwent transrectal ultrasound guided prostate biopsy. Haydarpaşa Numune Eğitim ve Araştırma Hastanesi Tıp Dergisi, Cilt: 52 - Sayı: 2, 83–87. https://ajindex.com/articles/535403

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