Journals / Haydarpaşa Numune Eğitim ve Araştırma Hastanesi Tıp Dergisi / 2013 / Cilt: 53 - Sayı: 3

The Effect of Smoking on Microalbuminuria Levels in Patients with Non Hypertensive Type 2 Diabetes Mellitus

HİPERTANSİF OLMAYAN TİP 2 DİABETES MELLİTUSLU HASTALARDA SİGARA KULLANIMININ MİKROALBUMİNÜRİ DÜZEYLERİ ÜZERİNE ETKİSİ

Pages
131–135
Publication Date
2022-10-17
DOI
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This was statistically significant (p=0.004).Conclusion: Smoking increases microalbuminuria levels in patients with type 2 diabetes mellitusindependently from the other factors.

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Objective & Hypothesis:Aim: To evaluate the effect of smoking on microalbuminuria levels in patients with type 2 diabetes mellitus.Materials and Methods: Microalbumin levels inurine of 51 smoking and 58 non smoking 108 patients with type 2 DM were compared.
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Key Findings & Data:Age, gender, BMI, arterial blood pressure,cholesterol levels, diabetes, age, and the regulation of the two groups were not statistically significant difference between them.Results: Study groups were composed of smokers (group1) and non smokers (group 2).
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Conclusion & Impact:This was statistically significant (p=0.004).Conclusion: Smoking increases microalbuminuria levels in patients with type 2 diabetes mellitusindependently from the other factors.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: To evaluate the effect of smoking on microalbuminuria levels in patients with type 2 diabetes mellitus.Materials and Methods: Microalbumin levels inurine of 51 smoking and 58 non smoking 108 patients with type 2 DM were compared. The patients with hypertension, hyperthyroidism,hypothyroidism, any kidney disease, congestiveheart failure and habit of heavy exercise wereexcluded from the study. Two groups were composed. Age, gender, BMI, arterial blood pressure,cholesterol levels, diabetes, age, and the regulation of the two groups were not statistically significant difference between them.Results: Study groups were composed of smokers (group1) and non smokers (group 2). Therewere no statistically significant difference between groups in terms of age, gender, body mass index, starving glucose levels, HbA1c levels,totalcholesterol, LDL, HDL, blood urea nitrogen andcreatinine levels. The mean microalbuminuria levels were found to be higher in smokers group(41.66+-6.37 mg/gün) than non smokers group(28.71+-3.10 mg/gün). This was statistically significant (p=0.004).Conclusion: Smoking increases microalbuminuria levels in patients with type 2 diabetes mellitusindependently from the other factors.

Özet

Amaç:Tip 2 diyabetes mellituslu hastalarda sigara kullanımının mikroalbuminüri düzeyleri üzerine etkisini araştırmak.Gereç ve Yöntem: 51 sigara kullanan ve 57 sigara kullanmayan tip 2 diyabetes mellituslu 108hastada 24 saatlik idrarda mikroalbuminüri düzeyleri karşılaştırıldı. Hipertansiyon, hiper ya dahipotiroidi, herhangi bir böbrek hastalığı, enfeksiyonu olan, kalp yetmezliği hastaları ve yoğun egzersiz yapan hastalar çalışma dışı bırakıldı. Yaş,cinsiyet, VKİ, arteryel tansiyon, kolesterol düzeyleri, diyabet yaşı ve regülasyonunda aralarındaistatistiksel anlamlı fark olmayan iki grup oluşturuldu.Bulgular: Çalışma grupları; sigara kullanımı yok(n=57) ve var (n=51) olarak kategorize edildi. İkigrup arasında yaş ortalamaları, cinsiyet oranlarıve VKİ değerleri açısından farklılık görülmedi.Gruplar arasında açlık kan şekeri, HbA1c, totalkolesterol, LDL kolesterol, HDL kolesterol, BUNve kreatinin ortalama değerleri arasında farklılıksaptanmadı. Sigara kullanan grupta mikroalbuminürinin ortalama değeri (41.66±6.37mg/gün),sigara kullanmayan gruba (28.71±3.10 mg/gün)göre daha yüksek olup, istatistiksel olarak anlamlı derecede farklılık saptandı (P=0.003).Sonuçlar: Sigara kullanımının tip 2 diabetes mellituslu hastalarda diğer fatörlerden bağımsız olarak mikroalbuminüri düzeylerini artırdığı görüldü.

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Cite This Article

KARATOPRAK, C., KAYATAŞ, K., YEŞİL, E. E., TEPE, M., DEMİRTUNÇ, R. (2022). The Effect of Smoking on Microalbuminuria Levels in Patients with Non Hypertensive Type 2 Diabetes Mellitus. Haydarpaşa Numune Eğitim ve Araştırma Hastanesi Tıp Dergisi, Cilt: 53 - Sayı: 3, 131–135. https://ajindex.com/articles/535382

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