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Journals / Haydarpaşa Numune Eğitim ve Araştırma Hastanesi Tıp Dergisi / 2015 / Cilt: 55 - Sayı: 1

Acute generalized exanthematous pustulosis (AGEP) due to the use of phenitoin: Case report

Fenitoin kullanımına bağlı gelişen akut jeneralize ekzantematöz püstülozis (agep) olgusu

Işıl BULUR
Koray HARMANCI
Abdülkadir KOÇAK
Hülya ANIL
Eylem KIRAL
Pages
69–73
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Also we aimed to emphasize the importance of anamnestic reports.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Acute generalized exanthematous pustulosis(AGEP) is a severe and rare eruption thatdevelops mostly from factors related todrugs.
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Key Findings & Data:It is characterized by a fever and apustular eruption on the erythematous skinwith an acute onset and without follicular localization.
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Conclusion & Impact:Also we aimed to emphasize the importance of anamnestic reports.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Acute generalized exanthematous pustulosis(AGEP) is a severe and rare eruption thatdevelops mostly from factors related todrugs. It is characterized by a fever and apustular eruption on the erythematous skinwith an acute onset and without follicular localization. Etiopathogenesis has not yetbeen fully explained. In this article, we presenta case of AGEP associated with phenytointhat developed in a patient followed up in theintensive care unit for uncontrolled seizures.Two years ago, maculopapüler rash occuredafter receving phenytoin at another servicein our hospital so ın this presentation; weaimed to emphasize that AGEP can rarelybe seen in childhood age and to review theclinical properties, diagnosis, treatment ofdisease. Also we aimed to emphasize the importance of anamnestic reports.

Özet

Akut jeneralize ekzantematöz püstülozis(AGEP), genellikle ilaçlara bağlı olarakgelişen ciddi ve seyrek bir erüpsiyondur.AGEP, ateşle karakterize, akut başlayanve foliküler olmayan eritematöz zeminüzerinde püstüler erüpsiyonlar ilekarakterizedir. Etyopatogenezi net olarakaydınlatılamamıştır. Burada yoğun bakımservisinde kontrol altına alınamayan nöbetlernedeniyle takip edilirken, fenitoine bağlıgelişen AGEPli bir olguyu sunduk. Anamneztekrar sorgulandığında, hastanın 2 yıl öncefarklı bir serviste yatarken fenitoin sonrasımakülopapüler döküntülerinin geliştiğiöğrenildi. Bu olguyu sunmamızdaki amacımızAGEPin çocuk yaş grubunda nadirengörülebildiğini vurgulamak, hastalığın kliniközelliklerini, tanı ve tedavisini gözdengeçirmek ve hasta takibinde anamnezin,tutulan kayıtların önemini vurgulamaktır.

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Cite This Article

BULUR, I., HARMANCI, K., KOÇAK, A., ANIL, H., KIRAL, E. (2022). Acute generalized exanthematous pustulosis (AGEP) due to the use of phenitoin: Case report. Haydarpaşa Numune Eğitim ve Araştırma Hastanesi Tıp Dergisi, Cilt: 55 - Sayı: 1, 69–73. https://ajindex.com/articles/535303

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