SavedAdd your journal

Journals / Hacettepe Journal of Biology and Chemistry / 2004 / Cilt: 33 - Sayı:

The antimicrobial effect of garlic (Allium sativum L.)

Selçuk HAZIR
Pages
93–100
Publication Date
2022-10-17
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The data suggest that garlic has potentially useful agent against Gram-positive and Gram-negative bacteria and yeast like C. albicans.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The in vitro antimicrobial effect of garlic which was harvested in Turkey was examined.
📊
Key Findings & Data:To evaluate whether garlic extract possessed antimicrobial activities, two analytical methods; 1) the agar-well diffusion technique 2) minimal inhibitory concentration (MIC) and minimum lethal concentration (MLC) were used.
💡
Conclusion & Impact:The data suggest that garlic has potentially useful agent against Gram-positive and Gram-negative bacteria and yeast like C. albicans.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The in vitro antimicrobial effect of garlic which was harvested in Turkey was examined. To evaluate whether garlic extract possessed antimicrobial activities, two analytical methods; 1) the agar-well diffusion technique 2) minimal inhibitory concentration (MIC) and minimum lethal concentration (MLC) were used. Escherichia coli. Bacillus anthracis, Pseudomonas aeruginosa and Candida albicans were used as clinical isolates. The data suggest that garlic has potentially useful agent against Gram-positive and Gram-negative bacteria and yeast like C. albicans.

🔖

Cite This Article

HAZIR, S. (2022). The antimicrobial effect of garlic (Allium sativum L.). Hacettepe Journal of Biology and Chemistry, Cilt: 33 - Sayı:, 93–100. https://ajindex.com/articles/529412

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (15)

  1. Singh, B., Falahee, MLB. and Adams, MR. Synergistic inhibition of Listeria monocytogenes by nisin and garlic extract. Food Microbiol. 18,133-139,2001
  2. Martin, K.W and Ernst, E. Herbal medicines for treatment of bacterial infections: a review of controlled clinical trials. J. Antimicrob. Chemother. 51,241-246,2003
  3. Ali, M., Thomson, M and Afzal, M. Garlic and Onions: their effect on eisanoid metabolism and its clinical relevance. Prostaglandins, Leukotrienes and Essential Fatty Acids. 62(2), 55-73,2000
  4. Sivam, G.P., Lampe, J.W., Ulness, B. Helicobacter pylori in vitro suspectibility to garlic (Allium sativum). FEMS Immunol. Med. Microbiol. 13,273-277,1996
  5. Jankers, D., Broek, E.V., Dooren, I.V., Thijs, C, Dorant, E., Hageman, G and Stobberingh, E. Antibacterial effect of garlic and omeprazole on Helicobacter pylori. J. Antimicrob. Chemother. 43, 837-839,1999
  6. Mahady, G.B., Matsuura, H. and Pendland, S.L. Allixin a phytoalexin from garlic, inhibits the growth of Helicobacter pylori x vitro. AJG. 96(12): 3454-3455,2001
  7. Me Elnay, J.C and Po, A.L.W. Garlic. The pharmaceut. J. 16,324-326,1991
  8. Sivam, P.G. Protection against Helicobacter pylori and other bacterial infections by Garlic. A. Soc. Nutrit. Sci. 1106-1108,2001
  9. Sanjay, K., Srivastava, X.H., Hong, X., Howard. A.Z., Moushumi, L.C., Rajesh. A and Shivendra, V.S. Mechanism of differential efficacy of garlic organosulfides in preventing benzo(a)pyrene-indeced cancer in mice. Cancer Letters. 118,61-67,1997
  10. Sakamoto, K., Lawson, L.D and Milner, J.A. Allyl sulfides from garlic suppress the in vitro proliferation of human A549 lung tumor cells. Nutrition and Cancer. 29(2), 152-156,1997
  11. Harris, J.C., Cottrell, S.L., Plummer, S and Lloyd, D. Antimicrobial properties of Allium sativum (garlic). Appl. Microbial Biotechnol. 57: 282-286, 2001
  12. Rabinkov, A., Miron, T., Mirelman, D., Wilchek. M., Glozman. S., Yavin, E and Weiner. L. S-Allylmercaptoglutathione: the reaction product af allicin with glutathione possesses SH-modifying and antioxidant properties. Biochimica et Biophysica Acta. 1499, 144-153,2000
  13. Hughes, B.G and Lawson, L.D. Antimicrobial effects of Allium sativum L. (garlic), Allium ampeloprasum (elephant garlic), and Allium cepa (onion), garlic compounds and commercial garlic supplement products. Phytother. Res. 5:154-158, 1991
  14. Ankri, S and Mirelman, D. Antimicrobial properties of allicin from garlic. Microbes and Infection. 2, 125-129,1999
  15. Koch, H.P