In view of these results, a high increase in pollution in the spring and the summer in the Meriç delta is caused by the active industrial and agricultural wastes from Turkey and Bulgaria which should be seriously considered.
📌 3 Key Takeaways
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Objective & Hypothesis:SOS inducing activity in samples obtained from the Meriç delta was evaluated with the umu test system using Salmonella typhimurium TA1535/ pSK1002, S. typhimurium NM1011 (overexpressed nitroreductase) and S. typhimurium NM2009 (overexpressed O-acetyltransferase) strains.
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Key Findings & Data:The Meriç delta is highly polluted especially in the spring and summer at Ergene origin in Turkey and at Enez at the downstream locations.
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Conclusion & Impact:In view of these results, a high increase in pollution in the spring and the summer in the Meriç delta is caused by the active industrial and agricultural wastes from Turkey and Bulgaria which should be seriously considered.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Abstract
SOS inducing activity in samples obtained from the Meriç delta was evaluated with the umu test system using Salmonella typhimurium TA1535/ pSK1002, S. typhimurium NM1011 (overexpressed nitroreductase) and S. typhimurium NM2009 (overexpressed O-acetyltransferase) strains. The Meriç delta is highly polluted especially in the spring and summer at Ergene origin in Turkey and at Enez at the downstream locations. However, results also confirm that the pollutants are not derived from nitroarenes but from other organic compounds. In view of these results, a high increase in pollution in the spring and the summer in the Meriç delta is caused by the active industrial and agricultural wastes from Turkey and Bulgaria which should be seriously considered.
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Cite This Article
DURUSOY, M., KAMBUR, S., ZORBEK, L., ÖZTÜRK, K. (2022). Evaluation of genotoxic potential of Meriç Delta by using Umu tests system. Hacettepe Journal of Biology and Chemistry, Cilt: 33 - Sayı:, 83–91. https://ajindex.com/articles/529410
Vargas V.M.F., Migliavacca S.B., Melo A.C., Horn R.C., Guidobono R.R., Sâ Ferreira l.C.F. and Pestana M.H.D. Genotoxicity assessment in aquatic environments under the influence of heavy metals and organic contaminants. Mutat Res 490,141-158,2001
Kamer 1. and Rinkevich B. In vitro application of the comet assay for aquatic genotoxicity: considering a primary culture versus a cell line. Toxicology in Vitro 16,177-184, 2002
Ohe T. Quantification of mutagenic/carcinogenic heterocyclic amines, MelQx, Trp-P-1, Trp-P-2 and PhIP, contributing highly to genotoxicity of river water. Mutat Res 393, 73-79,1997
Hamer B., Bihari N., Reifferscheid G., Zahn R.K., Müller W.E.G. and Batel R. Evaluation of the SOS/ wmw-test- post-treatment assay for the detection of genotoxic activities of pure compounds and complex enviromental mixtures. Mutat Res 466,161-171,2000
Dizer H., Wittekindt E., Fischer B. and Hansen P.D. The cytotoxic and genotoxic potential of surface water and wastewater effluents as determined by bioluminescense, wmw-assay and selected biomarkers. Chemosphere 46,225-233,2002 6. Rosenkranz H.S. and Mermelstein R. The genotoxicity, metabolism and carcinogenicity of nitrated polycyclic aromatic hydrocarbons. J Environ Sci Health C3,221-272, 1985
Weisburger J.H. Past, present and future role of carcinogenic and mutagenic N-substituted afyl compounds in human cancer, In king CM et al, (eds): Carcinogenic and mutagenic responses to aromatic amines and nitroarenes, Elsevier, New York, 3-19,1988
Kalebaşı A. Y. and Emir D. Investigation of chemical pollution of Meriç river, The Tenth of National Congress of Chemistry, The University of Uludağ, Bursa, Congress Book, pp.18,1994 9. Kalebaşı A.Y. and Emir D. To analyse of ammonia, calcium, magnesium, chlore, phosphate, some essential elements and determination of conductivity in Meriç river, The Twelfth of National Congress of Chemistry, The University of Trakya, Edirne, Congress Book, pp.715, 1998 10. Republic of Turkey Ministry of Energy and Natural Sources, State Hydraulic Works (T.C. Enerji ve Tabii Kaynaklar Bakanlığı, Devlet Su İşleri). Report of the investigation of pollution in Ergene river, General Directorate of State Hydraulic Works, Ankara, Turkey (1997)
Oda Y., Nakamura S., Oki I., Kato T. and Shinagawa H. Evaluation of the new system (umu test)for the detection of environmental muatgens and carcinogens. Mutat Res 147, 219-229,1985