Statistical analysis indicated that there is a significant difference between the serum selenium levels of two groups.
📌 3 Key Takeaways
🎯
Objective & Hypothesis:Selenium is an essential element and a cofactor required to maintain glutathione peroxidase activity.
📊
Key Findings & Data:Its deficiency may induce modification in the cellular antioxdative status and the appearence of different diseases such as cardiovascular diseases and cancer.
💡
Conclusion & Impact:Statistical analysis indicated that there is a significant difference between the serum selenium levels of two groups.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Abstract
Selenium is an essential element and a cofactor required to maintain glutathione peroxidase activity. Its deficiency may induce modification in the cellular antioxdative status and the appearence of different diseases such as cardiovascular diseases and cancer. This study was conducted to determine whether an association exists between serum selenium levels and ischaemic heart disease. Serum selenium concentrations of the test and control groups were measured with hydride generation atomic absorbtion spectrometry. Statistical analysis indicated that there is a significant difference between the serum selenium levels of two groups.
🔖
Cite This Article
İZBIRAK, A. (2022). Serum selenium levels in ischaemic heart disease. Hacettepe Journal of Biology and Chemistry, Cilt: 35 - Sayı: 2, 101–104. https://ajindex.com/articles/529379
Xia, J., Hill, K.E., and Burke, R.F., Biochemical studies of a selenium-deficient population in China: measurement of selenium, glutathione peroxidase and other oxidant defence indices in blood. J Nutr,119, 1318-1326, 1989
Magos, L., and Webb, M., The interaction of selenium with cadmium and mercury. CRC Crit Rev Toxicol,8, 1-42, 1980
Andersen, O., and Nielsen, J.B., Effects of simultaneous low-level dietary supplementation with inorganic and organic Se on blood and organ toxic levels of metals in mice. J Trace Elem Elect Health Dis, 7, 122, 1993
Hui-Min, J., Guo'an, H., Xi, C., and Hongjun, Z., Effect of selenium on the change in cadmium- induced distribution of trace elements in pregnant rats. Trace Elem Elect, 14, 9-12, 1997
Willett, W.C., Polk, B.F., Morris, J.S., Stanmpfer, M.J., Pressil, S., Rosner, B., Taylor, J.O., Schneider, K., and Hames, C.G., Prediagnostic serum selenium and risk of the cancer. Lancet, 2,130-134, 1983
Helzlsouer, K.J., Comstock, G.W., and Morris, J.S., Selenium, lycopene, alpha-tocopherol, beta-carotene, retinol and subsequent bladder cancer. Cancer Res, 49, 6144- 6148, 1989
Overvad, K., Selenium and cancer in role of trace elements for health promotion and disease prevention, Sandstrom, B., and Walter, P. (eds) Kargel, Basel, 141-149, 1998
Salonen, J.T., Salonen, R., Seppanen, K., Kantola, M., Paviainen, M., Alfthan, G., Maenpaa, P.H., Taskinen, E., and Rauramaa, R., Relationship of serum selenium and antioxidants to plasma lipoproteins, platelets aggregability and prevalent ischaemic heart disease in eastern Finnish men. Atherosclerosis, 70, 155-160, 1988
Korpela, H., Kumpulainen, J., Jussila, E., Kemila, S., Kaariainen, M., Kaariainen, T., and Sotaniemi, E.A., Effect of selenium supplementation after acute myocardial infarction. Res Commun Chem Pathol Pharmacol, 65, 249-252, 1989
Korpela, H., Selenium in cardiovascular diseases- an update. J Trace Elem Electrolytes Health Dis,7,115, 1993 11. Hattunen, J.K., Selenium and cardiovascular diseases- an update. Biomed and Environ Sci, 10, 220-226, 1997
Johansson,E., Selenium and its protection against the effects of mercury and silver. J Trace Elem Electrolytes Health Dis, 54, 273- 274, 1991
Arthur, J.R., and Beckett, G.J., Selenium deficiency and tyroid homone metabolism. In Selenium In Bioloy And Medicine, Wendel, A. (Ed.), Berlin, Springer, 1989