Adsorption of bovine serum albumin (BSA) on clinoptilolite

The purpose of the present work was to investigate the adsorption of BSA on clinoptilolite in aqueous media. In this study, batch adsorption experiments were carried out and the effects of pH, protein concentration, ionic strength and modification of zeolite on the adsorption process were examined. The optimum pH for adsorption was found to be 4.0. It was found that various treatments applied to modify clinoptilolite has a substantial effect on the adsorption. In adsorption studies, residual BSA concentration reached equilibrium in a short duration of 60 min. Maximum adsorption capacity value for clinoptilolite in the original form is 388.3 mg BSA/g zeolite (23.2 mg BSA/m2) and in the modified form ranges from 500-660 mg BSA/g zeolite (25-33 mg BSA/m2) showed that this adsorbent, clinoptilolite, was suitable for the adsorption of BSA from aqueous media.

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ÖZMAK, M., DUMANLI, A. G., YÜRÜM, Y., SAVAK, N. B., KARABAKAN, A., AKGÜL, M. (2022). Adsorption of bovine serum albumin (BSA) on clinoptilolite. Hacettepe Journal of Biology and Chemistry, Cilt: 36 - Sayı: 1, 21–29. https://ajindex.com/articles/529358

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