Larval food restriction and Iongevity: effects on the age specific mortality and mean longevity in natural populations of Drosophila melanogaster and Its Sibling D. simulans
We conclude that this non-universal phenomena could be expected on the fact that longevity, as a life history trait likely to be influenced by many genes is not independent of various background effects.
📌 3 Key Takeaways
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Objective & Hypothesis:In the study presented, we compare the effects of food restriction variation on longevity in Drosophila melanogaster and its sibling species D. simulans in natural populations in a sex based experimental design.
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Key Findings & Data:Our data show that rate of increase in age specific mortality parameter (b, from the classical logistic equation) and mean longevity are affected differently by the restriction.
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Conclusion & Impact:We conclude that this non-universal phenomena could be expected on the fact that longevity, as a life history trait likely to be influenced by many genes is not independent of various background effects.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Abstract
In the study presented, we compare the effects of food restriction variation on longevity in Drosophila melanogaster and its sibling species D. simulans in natural populations in a sex based experimental design. Our data show that rate of increase in age specific mortality parameter (b, from the classical logistic equation) and mean longevity are affected differently by the restriction. However, both age specific mortality parameter and the mean longevity are contributed by species, sex and population specific effects at different levels in response to food restriction variation. We conclude that this non-universal phenomena could be expected on the fact that longevity, as a life history trait likely to be influenced by many genes is not independent of various background effects.
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Cite This Article
ÖZSOY, E. D., YILMAZ, M., ÖNDER, B. Ş. (2022). Larval food restriction and Iongevity: effects on the age specific mortality and mean longevity in natural populations of Drosophila melanogaster and Its Sibling D. simulans. Hacettepe Journal of Biology and Chemistry, Cilt: 37 - Sayı: 1, 1–11. https://ajindex.com/articles/529322
Heilbronn, L.K., Ravussin, E. Calorie restriction and ageing: review of the literature and implications for studies in humans, Am. J. Clin. Nutr., 78:361-369, 2003. 2.Mockett, R.J., Cooper, T.M., Orr, W.C., Sohal, R.S. Effects of caloric restriction are species-specific, Biogerontology 7:157-160,2006. 3.Lee, KP., Simpson, S.J., Clissold, F.J., Brooks, R., William, J., Ballard, O., Taylor, P.W., Soran, N., and Raubenheimer, D., Lifespan and reproduction in Drosophila: New insights from nutritional geometry. PNAS 105:7,2498-2503,2008. 4.Chippindale, A.K., Leroi, A.M., Kim, S.B., Rose, M.R. Phenotypic plasticity and selection in Drosophila life-history evolution. I. Nutrition and the cost of reproduction, J. E vol I Biol.,; 6, 171-193, 1993. 5.Min K.-J. and Tatar, M., Drosophila diet restriction in practice: Do flies consume fewer nutrients? Mechanisms of ageing and development. 127,93-96, 2006. 6.Bourg, E.L. and Minois, N., Does dietary restriction really increase longevity in Drosophila melanogasteft Ageing research reviews, 4, 409-421, 2005. 7.Mair, W., Piper, M.D., Partridge, L. Calories do not explain • extension of lifespan by dietary restriction in Drosophila. PLoS Biol. 7, e223, 2005. 8.Piper, M.D. and Partridge, L., Dietary restriction in Drosophila: delayed ageing or experimental artefact? PLoS Genet. 3, e57, 2007. 9.Tu, M.-P, and Tatar, M., Juvenile diet restriction and the ageing and reproduction of adult Drosophila melanogaster, Ageing Cell, 2, 327-333, 2003. 10.Pletcher, S.D., Model fitting and hypothesis testing for age-specific mortality data, J. Evol. Biol., 12, 430-439, 1999. 11.Sokal, R. R. and F. J. Rohlf. Biometry: the principles and practice of statistics in biological research. 3rd edition. W. H. Freeman and Co.: New York. 887, pp. 1995. 12.Lewontin, R.C. On the measurement of relative variability. Syst. Zool., 15, 141-142, 1966.