Journals / Hacettepe Journal of Biology and Chemistry / 2015 / Cilt: 43 - Sayı: 3

Poly(hydroxyethyl methacrylate)-co-N-methacryloyl-(L)- histidine methyl ester Based Cryogel for the Removal of $Fe^{3+}$ from Human Plasma effected with Beta Thalassemia

Poli(hidroksietil metakrilat-N-metakrilo-L-Histidin metil ester) Temelli Kriyogel ile Beta talasemili İnsan Plazmasından$Fe^{3+}$’ün Uzaklaştırması

Pages
179–185
Publication Date
2022-10-17
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It was also observed that $Fe^{3+}$ could be repeatedly adsorbed and desorbed using poly(HEMA-MAH) cryogel without significant loss in its adsorption capacity.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:In this study, $Fe^{3+}$ adsorption was carried by using supermacroporous poly(2-hydroxyethyl methacrylate-Nmethacryloyl-(L)-histidine methyl ester) [poly(HEMA-MAH)] cryogel.
📊
Key Findings & Data:The influence of flow rate, pH, initial $Fe^{3+}$ concentration, and $Fe^{3+}$ adsorption from human plasma effected with beta thalassemia on the adsorption efficiency of the cryogel was investigated.
💡
Conclusion & Impact:It was also observed that $Fe^{3+}$ could be repeatedly adsorbed and desorbed using poly(HEMA-MAH) cryogel without significant loss in its adsorption capacity.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

In this study, $Fe^{3+}$ adsorption was carried by using supermacroporous poly(2-hydroxyethyl methacrylate-Nmethacryloyl-(L)-histidine methyl ester) [poly(HEMA-MAH)] cryogel. Poly(HEMA-MAH) cryogel was characterized by swelling tests and scanning electron microscopy. The influence of flow rate, pH, initial $Fe^{3+}$ concentration, and $Fe^{3+}$ adsorption from human plasma effected with beta thalassemia on the adsorption efficiency of the cryogel was investigated. The equilibrium swelling degree of poly(HEMA-MAH) cryogel was found to be 7.54 g $H_2$O/g cryogel.$Fe^{3+}$ adsorption capacity of poly(HEMA-MAH) cryogel from aqueous solution was estimated as 1.79 mg/g cryogel, while lower adsorption capacity was observed in human plasma (1.71 mg/g). It was also observed that $Fe^{3+}$ could be repeatedly adsorbed and desorbed using poly(HEMA-MAH) cryogel without significant loss in its adsorption capacity.

Özet

Bu çalışmada, $Fe^{3+}$ adsorpsiyonu, süpermakrogözenekli poli(2-hidroksietil metakrilat-N-metakrilo-(I)-histidin metil ester) [poli(HEMA-MAH)] kriyojeli kullanılarak incelenmiştir. Poli(HEMA-MAH) kriyojeli elektron mikroskop taraması ve şişme testleriyle karakterize edilmiştir. Akış hızı, pH, $Fe^{3+}$’ün başlangıç derişiminin $Fe^3$ adsorpsiyonuna etkileri incelenmiştir. Poli(HEMA-MAH) temelli kriyojelin denge şişme derecesi 7.54 g $H_2$0/g kriyojel olarak bulunmuştur. Poli(HEMA-MAH) temelli kriyojelin $Fe^{3+}$ adsorpsiyon kapasitesi 1.71 mg/g bulunmuştur. Önemli miktarda adsorpsiyon kapasitesi kaybı olmadan $Fe^{3+}$ iyonlarının P(HEMA-MAH) kriyojel ile adsorbe ve desorbe edildiği saptanmıştır.

🔖

Cite This Article

Alkan, H. (2022). Poly(hydroxyethyl methacrylate)-co-N-methacryloyl-(L)- histidine methyl ester Based Cryogel for the Removal of $Fe^{3+}$ from Human Plasma effected with Beta Thalassemia. Hacettepe Journal of Biology and Chemistry, Cilt: 43 - Sayı: 3, 179–185. https://ajindex.com/articles/529150

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (25)

  1. D. Purves, Trace Element Contamination of the Environment, Elsevier Science Publishers BV, Amsterdam, 1985
  2. B. Tang, L. Zhang, J. Zhang, Z. Z. Chen, Y.Wang, Spectrochim. Acta, 60 (2004) 2425
  3. M.C. Rouan, F. Marfil, P. Mangoni, R. Sechaud, H.Humbert, G. Maurer,. J. Chromatogr., B, 755 (2001) 203
  4. S. Ozkara, R. Say, C. Andac, Ind. Eng. Chem. Res., 47 (2008) 7849-7856 5. A. Denizli, B. Salih, E. Piskin, J. Biomater. Sci. Polym. Ed., 9 (1998) 175-187
  5. H. Yavuz, Y. Arica, A. Denizli, J. Appl.Polym. Sci., 82 (2001) 186-194
  6. M. Andac, E. Ozyapi, S. Senel, R. Say, A. Denizli, Ind. Eng.Chem. Res., 45 (2006) 1780-1786
  7. G. Baydemir, M. Andac, N. Bereli, R. Say, A. Denizli, Ind. Eng. Chem. Res., 46 (2007) 2843-2852
  8. M. McCoy, K. Kalghatgi, F.E. Regnier, N. Afeyan, J. Chromatogr. A, 743 (1996) 221–229
  9. E.B. Altıntas, A. Denizli, J. Chromatogr. B, 832 (2006) 216–223
  10. L. Uzun, R. Say, A. Denizli, React. Funct. Polym., 64 (2005) 93–102
  11. K. Thommes, M.R. Kula, Biotechnol. Prog., 11 (1995) 357–367
  12. T.B. Tennikova, B.J. Reusch, J. Chromatogr. A, 1065 (2005) 13–17
  13. N. Bereli, M. Andac, G. Baydemir, R. Say, I.Y. Galaev, A. Denizli, J. Chromatogr. A, 1190 (2008) 18–26
  14. F. Yılmaz, N. Bereli, H. Yavuz, A. Denizli, Biochem. Eng. J., 43 (2009) 272–279
  15. H. Alkan, N. Bereli, Z. Baysal, A. Denizli, Biochem. Eng. J., 45 (2009) 201–208
  16. G. Baydemir, N. Bereli, M. Andac, R. Say, I.Y. Galaev, A. Denizli, React. Funct. Polym., 69 (2009) 36–42
  17. G. Baydemir, N. Bereli, M. Andac, R. Say, I.Y. Galaev, A. Denizli, Colloid Surf. B, 68 (2009) 33–38
  18. L. Uzun, H. Yavuz, R. Say, A. Ersoz, A. Denizli, Ind. Eng. Chem. Res., 43 (2004) 6507–6513
  19. A. Cavus, Z. Baysal, H. Alkan, Colloids and Surfaces B: Biointerfaces, 107 ( 2013) 84–89 21. V.I. Lozinsky, I.Y. Galaev, F.M. Plieva, I.N. Savina, H. Jungvid, B. Mattiasson, Trends Biotechnol., 21 (2003) 445–451
  20. P. Arvidsson, F.M. Plieva, V.I. Lozinsky, I.Y. Galaev, B. Mattiasson, J. Chromatogr., A 986 (2003) 275–290
  21. V.I. Lozinsky, F.M. Plieva, I.Y. Galaev, B. Mattiasson, Bioseparation 10 (2002) 163–188
  22. W. Noppe, F.M. Plieva, K. Vanhoorelbeke, H. Deckmey, M. Tuncel, A.Tuncel, I.Y. Galaev, B. Mattiasson, J. Biotechnol., 131 (2007) 293–299
  23. P. Arvidsson, F.M. Plieva, I.N. Savina, V.I. Lozinsky, S. Fexby, L. Bulow, I.Y. Galaev, B. Mattiasson, J. Chromatogr. A, 977 (2002) 27–38
  24. B. Garipcan, A. Denizli, Macromol. Biosci., 2 (2002) 135-144
  25. E. Valdman, L. Erijman, F.L.P