Journals / Hacettepe Journal of Biology and Chemistry / 2017 / Cilt: 45 - Sayı: 2

Trivalent Cr(III) and Hexavalent Cr(VI) Chromium Affect Morphology and Diversity of Hematopoietic Outcome in Japanese Quail (Coturnix Japonica)

Trivalent Cr(III) ve Hekzavalent Cr(VI) Krom iyonlarının Japon Bıldırcınının (Coturnix Japonica) Morfolojisi ve Hematopoietik Sonuçları Üzerine Etkisi

Pages
263–268
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The surface of erythrocytes, thrombocytes and heterophils was significantly reduced (p

📌 3 Key Takeaways

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Objective & Hypothesis:Chromium is a naturally occurring heavy metal found commonly in the environment in trivalent Cr(III) and hexavalent Cr(VI) forms.
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Key Findings & Data:Cr(VI) compounds are rated as potential carcinogens.
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Conclusion & Impact:The surface of erythrocytes, thrombocytes and heterophils was significantly reduced (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Chromium is a naturally occurring heavy metal found commonly in the environment in trivalent Cr(III) and hexavalent Cr(VI) forms. Cr(VI) compounds are rated as potential carcinogens. The study covered an analysis of the effect of Cr(III) as CrCl3 (chromium chloride) and Cr(VI) as CrO3 (chromium oxide) on hematological parameters of Japanese quail (Coturnix japonica). Chromium was added to food and water ad libitium and the experiment lasted 20 days. Significant differences in values of heterophils and lymphocytes were obtained with the tendency of reducing the number of these blood cells. The surface of erythrocytes, thrombocytes and heterophils was significantly reduced (p

Özet

Krom, üç değerlikli Cr(III) ve altı değerlikli Cr(VI) formlarında yaygın olarak bulunan, doğal olarak oluşan bir ağır metaldir. Cr(VI) bileşikleri potansiyel kanserojenler olarak sınıflandırılmıştır. Çalışma, Japon bıldırcınlarının (Coturnix japonica) hematolojik parametrelerinde Cr(III)’ün CrCl3 (krom klorür) ve Cr(VI)’nın CrO3 (krom oksit) olarak etkisinin analizini kapsamaktadır. Krom yiyeceklere ve içeceklere ilave edilmiş ve deneyler 20 gün boyunca sürdürülmüştür. Kan hücrelerinin sayısında azalma eğilimi ile heterofiller ve lenfosit değerlerinde belirgin farklılıklar elde edilmiştir. Eritrositlerin, trombositlerin ve heterofillerin yüzeyi önemli derecede küçülmüştür (p

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Cite This Article

FOCAK, M., ALİJAGİC, A., SULJEVIC, D. (2022). Trivalent Cr(III) and Hexavalent Cr(VI) Chromium Affect Morphology and Diversity of Hematopoietic Outcome in Japanese Quail (Coturnix Japonica). Hacettepe Journal of Biology and Chemistry, Cilt: 45 - Sayı: 2, 263–268. https://ajindex.com/articles/529106

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References (1)

  1. B. Yucesoy, S. Mirshahidi, C. Yucesoy, A. Karakaya, In vitro effects of various metals on natural killer cell activity in cultured human lymphocytes. Immunopharmacol. Immunotoxicol., 21 (1999) 599. J.Y. Wang, B.H. Wicklund, R.B. Gustilo, D.T. Tsukayama, Prosthetic metals impair murine immune response and cytokine release in vivo and in vitro, J. Orthop. Res., 15 (1997) 688. 19. P. Borella, S. Manni, A. Giardino, Cadmium, nickel, chromium and lead accumulate in human lymphocytes and interfere with PHA-induced proliferation. Journal of trace elements and electrolytes in health and disease, J. Trace. Elem. Electrolytes. Health. Dis. 4 (1990) 87. C. Faleiro, I. Godinho, U. Reus, M. de Sousa, Cobaltchromium-molybdenum but not titanium-6aluminium4vanadium al-loy discs inhibit human T cell activation in vitro, Biometals, 9 (1996) 321. S. Richa, R.K. Upreti, P.K. Seth, U.C. Chaturvedi, Effects of chromium on the immune system, FEMS Immunol. Med. Microbiol., 34 (2002) 1. M. Myslak, K. Kosmider, Kinetics of cell division in peripheral blood lymphocytes of stainless steel welders, Medycyna Pracy, 48 (1997) 261. Y. Loubieres, A. de Lassence, M. Bernier, A. VieillardBaron, J. M. Schmitt, B. Page, F. Jardin, Acute, fatal, oral chromic acid poisoning, J. Toxicol. Clin. Toxicol., 37 (1999) 333. B.K. Sharma, P.C. Singhal, K.S. Chugh, Intravascular haemolysis and acute renal failure following potassium dichromate poisoning, Postgrad. Med. J., 54 (1978) 414 K. Sugden, D. Stearns, The role of chromium (V) in the mechanism of chromate-induced oxidative DNA damage and cancer, J. Environ. Pathol. Toxicol. Oncol., 19 (1999) 215. G. De Mattia, M.C. Bravi, O. Laurenti, O. De Luca, A. Palmeri, A. Sabatucci, G. Mendico, A. Ghiselli, Impairment of cell and plasma redox state in subjects professionally exposed to chromium, Am. J. Ind. Med., 46 (2004) 120. A. Dayan, A. Paine, Mechanisms of chromium toxicity, carcinogenicity and allerginicity: Review of the literature from 1985 to 2000, Hum. Exp. Toxicol., 20 (2001) 439. N. Tonks, PTP1B: From the sidelines to the front lines! FEBS, Letters, 546 (2003) 140. I. Kat, J. Vogelman, V. Dilman, J. Karkoszka, K. Frenkel, N. Durr, P. Toniolo, Effect of supplementation with chromium picolinate on antibody titers to 5— hydroxymethyl uracil, Eur. J. Epidemiol., 14 (1998) 621 T. Ozawa, A. Hanaki, Spin-trapping studies on the reactions of Cr(III) with hydrogen peroxide in the presence of biological reductants: is Cr(III) non-toxic?, Int. J. Biochem.,