Journals / Hacettepe Journal of Biology and Chemistry / 2020 / Cilt: 48 - Sayı: 3

A Retrospective Study on Urinary Tract Infection Agents Isolated from Children and Their Antibiotic Susceptibility

Çocuklardan İzole Edilen İdrar Yolu Enfeksiyonu Etkenlerinin ve Antibiyotik Duyarlılıklarının Retrospektif Değerlendirilmesi

Pages
265–274
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Among the age groups, 0-2 age group was quite diversein terms of infection agents and antibiotic resistance values of these agents were significantly high in this group (p

📌 3 Key Takeaways

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Objective & Hypothesis:Antibiotics are important agents in the treatment of urinary tract infection (UTI).
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Key Findings & Data:Antibiotic inappropriate resistance is one of the most importantproblems of increased uropathogenic resistance, especially in pediatric urology.
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Conclusion & Impact:Among the age groups, 0-2 age group was quite diversein terms of infection agents and antibiotic resistance values of these agents were significantly high in this group (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Antibiotics are important agents in the treatment of urinary tract infection (UTI). However, the use of antibiotics is animportant risk factor causing antibiotic resistance. Antibiotic inappropriate resistance is one of the most importantproblems of increased uropathogenic resistance, especially in pediatric urology. Deficiencies in empirical prescriptionpractices can make this problem even worse. In this study, the demographic characteristics of pediatric patients, UTI agents,and antibiotic resistance of these agents were retrospectively evaluated by an automated system. The data from 719 UTIagents isolated from children were separately analyzed for four different age groups (0-2, 2-6, 6-12, and 12-17). The mostcommonly isolated infection agents were Escherichia coli (68.01%), Klebsiella pneumoniae (19.75%), Klebsiella oxytoca (3.34%),Enterobacter cloacae (2.23%), and Pseudomonas aeruginosa (1.95%). Among the age groups, 0-2 age group was quite diversein terms of infection agents and antibiotic resistance values of these agents were significantly high in this group (p

Özet

Antibiyotikler idrar yolu enfeksiyonlarının tedavisinde önemli bir dayanak noktası olmasına rağmen, bilinçsiz kullanımları antibiyotik direncinin gelişimi için önemli bir risk faktörüdür. Antibiyotik direnci, özellikle çocuk ürolojisinde, artan üropatojen direncinin en önemli sorunlarından bir olarak karşımıza çıkmaktadır. Ampirik reçete uygulamalarındaki eksiklikler bu sorunu daha da kötüleştirmektedir. Bu çalışmada; pediatrik hastaların demografik özellikleri, idrar yolu enfeksiyonu etkenleri ve bu etkenlerin antibiyotik direnç durumları otomatize sistem ile retrospektif olarak değerlendirilmiştir. Çocuklardan izole edilen 719 idrar yolu enfeksiyonu etkeninden elde edilen veriler dört pediatrik yaş grubu (0-2 yaş, 2-6 yaş, 6-12 yaş ve 12-17 yaş) için ayrı ayrı analiz edildi. En sık izole edilen enfeksiyon etkenleri sırasıyla; Escherichia coli (%68.01), Klebsiella pneumoniae (%19.75), Klebsiella oxytoca (%3.34), Enterobacter cloacae (%2.23) ve Pseudomonas aeruginosa (%1,95) şeklindedir. Yaş grupları içerisinde; 0-2 yaş grubu enfeksiyon etkenleri açısından oldukça çeşitlilik göstermektedir. Aynı zamanda; bu grup içerisinde bu etkenlerin sahip olduğu antibiyotik dirençlerinin anlamlı bir şekilde yüksek olduğu saptanmıştır (p

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Cite This Article

İDİL, N., RAD, A. Y., CANDAN, E. D. (2022). A Retrospective Study on Urinary Tract Infection Agents Isolated from Children and Their Antibiotic Susceptibility. Hacettepe Journal of Biology and Chemistry, Cilt: 48 - Sayı: 3, 265–274. https://ajindex.com/articles/528970

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