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Journals / Hacettepe Journal of Biology and Chemistry / 2020 / Cilt: 48 - Sayı: 4

Synthesis and Antimicrobial Activities of some Antipyrine-Triazole-Conazoles

Bazı Antipirin-Triazol-Konazollerin Sentezi ve Antimikrobiyal Aktiviteleri

Hacer BAYRAK
Pages
381–387
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Also among the conazoles compound 4b and 4c showed good antitubercular activity.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Starting from antipyrine-triazole moiety some new kind of conazoles were synthesized.
📊
Key Findings & Data:Among them compound 3 which is anreduction product of compound 2 showed very good antitubercular activity against Mycobacterium smegmatis comparedwith Streptomycin standard drug.
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Conclusion & Impact:Also among the conazoles compound 4b and 4c showed good antitubercular activity.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Starting from antipyrine-triazole moiety some new kind of conazoles were synthesized. The synthesized compounds werescreened for their antimicrobial activities against some test microorganisms. Among them compound 3 which is anreduction product of compound 2 showed very good antitubercular activity against Mycobacterium smegmatis comparedwith Streptomycin standard drug. Also among the conazoles compound 4b and 4c showed good antitubercular activity.

Özet

Antipirin-triazol içeriğinden başlayarak bazı yeni konazoller sentezlendi. Sentezlenen bileşikler, bazı test mikroorganizmalarına karşı antimikrobiyal aktiviteleri açısından tarandı. Bunlar arasında, bileşik 2’nin bir indirgeme ürünü olan 3 nolu bileşik, Streptomisin standart ilacı ile karşılaştırıldığında Mycobacterium smegmatis’e karşı çok iyi bir antitüberküloz aktivite göstermiştir. Ayrıca konazoller arasında 4b ve 4c nolu bileşikler iyi bir antitüberküloz aktivite göstermiştir.

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Cite This Article

BAYRAK, H. (2022). Synthesis and Antimicrobial Activities of some Antipyrine-Triazole-Conazoles. Hacettepe Journal of Biology and Chemistry, Cilt: 48 - Sayı: 4, 381–387. https://ajindex.com/articles/528962

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