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Journals / Hacettepe Dişhekimliği Fakültesi Derg.(. Clinical Dentistry and Research) / 2008 / Cilt: 32 - Sayı: 2

Evaluation of antibiotic susceptibility of enterococcus faecalis isolated from deciduous and permanent tooth root canals

Süt ve kalıcı diş kök kanallarından izole edilen enterococcus faecalis'in antibiyotik duyarlılık profillerinin incelenmesi

Cemal ERONAT
Özant ÖNÇAĞ
Ataç UZEL
Dilşah ÇOĞULU
Semiha C. AKSOY
Pages
39–44
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: A high prevalence of resistance to erythromisin was found, whereas all isolates were susceptible or showed intermediate susceptibility to other tested antibiotics.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: Enterococcus faecalis strains with multiple antibiotic resistances can cause infections that are difficult to treat.
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Key Findings & Data:Materials and Methods: Twenty E. faecalis isolates were detected among 145 different root canals and were tested for their antibiotic susceptibilities against ampisilin, erythromycin, cloramphenicol, vancomycin, canamycin, methicillin, azithromycin and tetracycline.
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Conclusion & Impact:Conclusion: A high prevalence of resistance to erythromisin was found, whereas all isolates were susceptible or showed intermediate susceptibility to other tested antibiotics.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: Enterococcus faecalis strains with multiple antibiotic resistances can cause infections that are difficult to treat. The aim of this study was to test in vitro susceptibility of E. faecalis in deciduous and permanent tooth root canals against different antibiotics. Materials and Methods: Twenty E. faecalis isolates were detected among 145 different root canals and were tested for their antibiotic susceptibilities against ampisilin, erythromycin, cloramphenicol, vancomycin, canamycin, methicillin, azithromycin and tetracycline. Minimal inhibitory concentrations (MICs) were determined and E. faecalis strains classified as susceptible or resistant according to the guidelines of National Committee for Clinical Laboratory Standards (NCCLS). Results: Among all samples from symptomatic and asymptomatic cases, E. faecalis was detected in 2% (%3,2) of symptomatic cases and 18 % (%21,7) of asymptomatic cases. The difference between the groups was statistically significant (p = 0,001). Conclusion: A high prevalence of resistance to erythromisin was found, whereas all isolates were susceptible or showed intermediate susceptibility to other tested antibiotics.

Özet

Amaç: Yaygın olarak kullanılan birçok antibiyotik karşısında dirençli olan Enterococcus faecalis suşları, tedavisi oldukça güç infeksiyonlara neden olabilmektedir. Bu çalışmanın amacı, süt ve kalıcı diş kanallarından izole edilen E. faecalis suşlarının in vitro olarak farklı antibiyotiklere karşı duyarlılık profillerinin çıkarılmasıdır. Gereç ve Yöntem: Çalışmada 145 farklı kök kanalından izole edilen 20 E. faecalis izolatının ampisilin, eritromisin, kloramfenikol, vankomisin, kanamisin, metisilin, azitromisin ve tetrasiklin karşısındaki duyarlılık profilleri incelendi. National Committee for Clinical Laboratory Standards (NCCLS)'a gore minimal inhibisyon konsantrasyonu sonuçları duyarlı ya da dirençli olarak değerlendirildi. Bulgular: Semptomatik ve asemptomatik olgulardan alınan örnekler kültür yöntemi ile incelendiğinde semptomatik olguların yalnızca 2'sinde (%3,2) E. faecalis varlığı tespit edilirken, asemptomatik olguların 18'inde (%21,7) E. faecalis varlığı saptanmıştır. Gruplar arasındaki farklılığın istatistiksel olarak anlamlı olduğu tespit edildi (p = 0,001). Sonuç: Eritromisine karşı yüksek oranda dirençlilik saptanırken, suşların test edilen diğer antibiyotikler karşısında duyarlı ya da orta düzeyde duyarlı oldukları tespit edildi.

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Cite This Article

ERONAT, C., ÖNÇAĞ, Ö., UZEL, A., ÇOĞULU, D., AKSOY, S. C. (2022). Evaluation of antibiotic susceptibility of enterococcus faecalis isolated from deciduous and permanent tooth root canals. Hacettepe Dişhekimliği Fakültesi Derg.(. Clinical Dentistry and Research), Cilt: 32 - Sayı: 2, 39–44. https://ajindex.com/articles/528409

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