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Journals / Göztepe Tıp Dergisi / 2007 / Cilt: 22 - Sayı: 4

Leg ulcers associated with factor V leiden mutation

Faktör V leiden mutasyonuna bağlı bacak ülserleri

İlkin ZİNDANCI
Emek KOCATÜRK
Mukaddes KAVALA
Zafer TÜRKOĞLU
Melek KOÇ
Seyhan BEYHAN
Pages
153–155
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Risk of venous thrombosis is substantially increased in patients with factor V Leiden mutation.Herein we report two cases with factor V Leiden mutation which responded dramatically to oral anticoagulation therapy.

📌 3 Key Takeaways

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Objective & Hypothesis:Venous leg ulcers constitute 70 % of all leg ulcers which is a serious consequence of postthrombotic syndrome.
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Key Findings & Data:Immobilisation, surgery, trauma, pregnancy, oral contraceptive drugs and some coagulation defects have been reported to be risk factors for venous thrombosis.
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Conclusion & Impact:Risk of venous thrombosis is substantially increased in patients with factor V Leiden mutation.Herein we report two cases with factor V Leiden mutation which responded dramatically to oral anticoagulation therapy.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Venous leg ulcers constitute 70 % of all leg ulcers which is a serious consequence of postthrombotic syndrome. Immobilisation, surgery, trauma, pregnancy, oral contraceptive drugs and some coagulation defects have been reported to be risk factors for venous thrombosis. Activated protein C resistance is the most frequent cause of hereditary thrombophilia which is mostly associated with a point mutation in factor V protein. Risk of venous thrombosis is substantially increased in patients with factor V Leiden mutation.Herein we report two cases with factor V Leiden mutation which responded dramatically to oral anticoagulation therapy.

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Cite This Article

ZİNDANCI, İ., KOCATÜRK, E., KAVALA, M., TÜRKOĞLU, Z., KOÇ, M., BEYHAN, S. (2022). Leg ulcers associated with factor V leiden mutation. Göztepe Tıp Dergisi, Cilt: 22 - Sayı: 4, 153–155. https://ajindex.com/articles/526280

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