Journals / Göztepe Tıp Dergisi / 2011 / Cilt: 26 - Sayı: 4

The efficency of single dose methotrexate treatment with ectopic pregnancy

Ektopik gebeliklerde tek doz metotreksat tedavisinin etkinliği

Pages
148–151
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Less tubal damage occurs by the medical treatment, it decreases the morbidity for anesthesia and surgery.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The efficiency of single dose methotrexate treatment applied on patients with ectopic pregnancy is researched.Materials and method: 30 patients in between ages of 21 and 40 who have received single dose MTX treatment due to ectopic pregnancy is included in the study.
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Key Findings & Data:Serum B-hCG levels are monitored in accordance with the single dose MTX protocol.Results: The average age of the 30 cases taken in the study is 30.63±4.36.
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Conclusion & Impact:Less tubal damage occurs by the medical treatment, it decreases the morbidity for anesthesia and surgery.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: The efficiency of single dose methotrexate treatment applied on patients with ectopic pregnancy is researched.Materials and method: 30 patients in between ages of 21 and 40 who have received single dose MTX treatment due to ectopic pregnancy is included in the study. All the patients were stabile as hemodynamically. The serum B-hCG levels, USG findings prior to the MTX treatment are recorded. Serum B-hCG levels are monitored in accordance with the single dose MTX protocol.Results: The average age of the 30 cases taken in the study is 30.63±4.36. The B-hCG levels of the cases as changing in between 160 and 10910, their average is 2386.80±2498.68. The MTX doses they use as changing in between 50 mg and 100 mg, its average is 67.67±13.50. While 18 (60 %) of the cases had no previous surgical history. While the mass size of 6 (20 %) of the cases is below 4 cm, in 24 (80 %) of cases it is between 5 cm and 5.5 cm. 4 (13.3 %) of the cases is receiving additional dose of MTX. Laparotomy is applied on 3 (10 %) of the cases due to tubal rupture developing during the treatment.Conclusion: The medical treatment to be applied on non-ruptured ectopic pregnancies has many advantages. Less tubal damage occurs by the medical treatment, it decreases the morbidity for anesthesia and surgery.

Özet

Amaç: Ektopik gebelik tanısı alan hastalarda uygulanan tek doz metotreksat tedavisinin etkinliği araştırıldı. Gereç ve Yöntem: Çalışmaya ektopik gebelik nedeniyle tek doynetotreksat (MTX) tedavisi almış yaşları 21 ile 40 arasında değişmekte olan 30 hasta dahil edildi. Hastaların tümü hemodinamik olarak stabildi. MTX tedavisine başlamadan önceki serum human koryonik gonadotropin (B-hCG) seviyeleri, ultrasonografi (USG) bulguları kaydedildi. Tek doz MTX protokolüne uygun şekilde serum B-hCG düzeyleri takip edildi. Bulgular: Çalışmaya alınan 30 olgunun ortalama yaşları 30.63±4.36'dır. Olguların BHCG düzeyleri 160 ile 10910 arasında değişmekte olup, ortalaması 2386.80±2498.68'dir. Kullandıkları MTX dozları 50 mg ile 100 mg arasında değişmekte olup, ortalaması 67.67±13.50 mg'dır. 8'inin (% 60) geçirilmiş cerrahi öyküsü yoktur. Olguların 6'sının (% 20) kitle boyutu 4 cnı'nin altında iken, 24'ünün (% 80) 4 cm ile 5.5 cm arasındadır. Olguların 4'ü (% 13.3) ek doz MTX tedavisi almıştır. Olguların 3'üne (% 10) tedavi sırasında gelişen tubal rüptür nedeniyle laparotomi yapılmıştır. Sonuç: Riiptüre olmamış ektopik gebeliklerde uygulanacak medikal tedavinin birçok üstünlüğü vardır. Medikal. tedavi ile daha az tubal hasar meydana gelmekte, anesteziye, cerrahiye ait morbidite azalmaktadır.

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Cite This Article

TURGUT, A., SÜER, N., GÖRÜK, Y. N., PELİN, Ç. F. (2022). The efficency of single dose methotrexate treatment with ectopic pregnancy. Göztepe Tıp Dergisi, Cilt: 26 - Sayı: 4, 148–151. https://ajindex.com/articles/526142

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