Journals / Göztepe Tıp Dergisi / 2013 / Cilt: 28 - Sayı: 1

Effect of magnesium sulfate infusion on anaesthetic requirement and analgesia during gynecologic oncology surgery

Jinekolojik onkoloji ameliyatlarında magnezyum sülfat infüzyonunun intraoperatif anestezik gereksinimi ve postoperatif analjezi üzerine etkisi

Pages
7–13
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: IV administration of Mg sulfate in our dose, had no effect on postoperative pain and intraoperative propofol and remifentanil consumption.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: We tested magnesium infusion for intraoperative anaesthetic requirement and postoperative analgesia during and after gynecologic oncology surgery.
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Key Findings & Data:The magnesium group (n=16) received an initial dose of 30 mg/kg followed by 10 mg/kg/h over 20 h.
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Conclusion & Impact:Conclusion: IV administration of Mg sulfate in our dose, had no effect on postoperative pain and intraoperative propofol and remifentanil consumption.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: We tested magnesium infusion for intraoperative anaesthetic requirement and postoperative analgesia during and after gynecologic oncology surgery. Material and Methods: In a randomized, single blinded study, patients were assigned to two groups. The magnesium group (n=16) received an initial dose of 30 mg/kg followed by 10 mg/kg/h over 20 h. The control group (n=15) received place- bo. Blood samples were obtained before magnesium administ- ration, 90 minutes and 24 hours following initial magnesium administration. Plasma Mg were investigated. Results: There were no significant change between two groups in intraoperative propofol and remifentanil requirements. There were no significant change between two groups in seda- tion score, pain score, heart rate, mean arterial blood pressu- re, respiratory rate, delivery and demand on PCA device during postoperative 24 h period. Conclusion: IV administration of Mg sulfate in our dose, had no effect on postoperative pain and intraoperative propofol and remifentanil consumption.

Özet

Amaç: Çalışmamızda propofol ve remifentanil bazlı total intravenöz anestezi ve epidural analjezi uygulanan jinekolojik kanser ameliyatlarında intraoperatif ve postoperatif ağrı kontrolünde adjuvan ajan olarak kullandığımız magnezyum sülfatın intraoperatif anestezik gereksinimi ve postoperatif analjezi üzerine etkisini araştırdık.Gereç ve Yöntem: Hastalar iki gruba ayrıldı. Magnezyum gru- buna (n=16) 30 mg/kg başlangıç dozunu takiben 10 mg/kg/ saat magnezyum sülfat 20 saat süreyle uygulandı. Kontrol gru- buna (n=15) eşdeğer volümde % 0. 9 NaCl uygulandı. Postoperatif dönemde analjezi hasta kontrollü epidural anal- jezi yöntemiyle sağlandı. Magnezyum uygulamasından önce, 90. dk. ve 24. saatte alınan kan örneklerinde Mg ölçümleri yapıldı. Bulgular: İki grup arasında intraoperatif dönemdeki propofol ve remifentanil gereksinimi; postoperatif 30. dk., 6., 12. ve 24. saatteki kalp atım hızı, ortalama arter kan basıncı, solunumsayısı, “verbal numeric rating scale” değerleri, sedasyon skoru, 24. saatteki sunum ve istek sayıları açısından anlamlı fark saptanmadı.Sonuç: Jinekolojik kanser operasyonlarında intraoperatif ve postoperatif ağrı tedavisinde adjuvan ajan olarak kullandığımız magnezyum sülfatın uyguladığımız dozda analjezik etkisi nin olmadığı düşüncesindeyiz.

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Cite This Article

ALAY, F. Ü., EROLÇAY, H. (2022). Effect of magnesium sulfate infusion on anaesthetic requirement and analgesia during gynecologic oncology surgery. Göztepe Tıp Dergisi, Cilt: 28 - Sayı: 1, 7–13. https://ajindex.com/articles/526039

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