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Journals / Gazi Üniversitesi Fen Bilimleri Enstitüsü Dergisi / 2002 / Cilt: 15 - Sayı: 1

Determination of the crystallografic data of metoprolol tartrate by using X-ray powder diffraction pattern

X-ışınları toz kırınım deseninden metoprolol tartarat'ın kristalografik verilerinin tayin edilmesi

Sevim TÜRKTEKİN
Mehmet AKKURT
Pages
233–244
Publication Date
2022-10-18
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The analytical results and the TREOR90 program outputs are well-adjusted.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:It was investigated the powder diffraction pattern of metoprolol tartrate which is an effective substance of medicine, recorded by using the X-ray powder diffraction.
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Key Findings & Data:The results of the analytical procedure are, for form 1 a = 9.749(5) Â, b = 11.337(5) Â, c = 13.521(6) Â, and for form 2a = 6.740(4) Â, b = 8.27(1) Â, c = 12.36(1) Â.
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Conclusion & Impact:The analytical results and the TREOR90 program outputs are well-adjusted.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

It was investigated the powder diffraction pattern of metoprolol tartrate which is an effective substance of medicine, recorded by using the X-ray powder diffraction. It was determined that sample contains two different orthorhombic forms. The cell parameters of these two forms were obtained. The results of the analytical procedure are, for form 1 a = 9.749(5) Â, b = 11.337(5) Â, c = 13.521(6) Â, and for form 2a = 6.740(4) Â, b = 8.27(1) Â, c = 12.36(1) Â. The results obtained by using the TREOR90 program are also; for form l:a= 9.751(4) Â, b = 11.336(5) Â, c = 13.522(6) Â and for form 2; a = 6.746(4) Â, b = 8.263(10) Â, c = 12.356(12) Â. The analytical results and the TREOR90 program outputs are well-adjusted.

Özet

Bir ilaç etken maddesi olan metoprolol tartarat'ın X-ışınları toz kırınım tekniği ile alınan kırınım deseni değerlendirildi. Numunenin iki farklı ortorombik form içerdiği tesbit edildi. Bu iki formun birim hücre parametreleri tayin edildi ve kırınım desenlerindeki pikler indislendi. Analitik işlem sonucu bulunan değerler 1. form için , a = 9.749(5) Â, b = 11.337(5) A, c = 13.521(6) Â, 2. form için, a = 6.740(4) Â,,e = 8.27(1) Â, c = 12.36(1) A'dur. TREOR90 programı kullanılarak ise; 1. form için;a = 9.751(4) Â, b = 11.336(5) Â, c = 13.522(6) A, 2. form için; a = 6.746(4) Â, b = 8.263(10) Â, c = 12.356(12) Â hesaplandı. Analitik ve TREOR90 programı ile bulunan değerlerin uyumlu olduğu görüldü.

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Cite This Article

TÜRKTEKİN, S., AKKURT, M. (2022). Determination of the crystallografic data of metoprolol tartrate by using X-ray powder diffraction pattern. Gazi Üniversitesi Fen Bilimleri Enstitüsü Dergisi, Cilt: 15 - Sayı: 1, 233–244. https://ajindex.com/articles/522308

References (1)

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