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Journals / Gazi Üniversitesi Diş Hekimliği Fakültesi Dergisi / 2006 / Cilt: 23 - Sayı: 2

Effects of serum estradiol levels on gingival crevicular fluid IL-IB and ALP levels in postmenapousal women

Postmenapozal bayanlarda serum östrojen seviyelerinin dişeti oluğu sıvısı IL-IB ve ALP seviyelerine etkisi

Muhittin SERDAR
Özlem DALTABAN
Işıl SAYGUN
Belgin BAL
Köksal BALOŞ
Pages
105–109
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

A positive statistical correlation was found between total ALP levels and IL-16 levels (r=0.436, p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The aim of this study was to determine how serum estrogen levels in postmenapousal wonien may possibly influence the gin-gival crevicular fluid (GCF) interleukin-1 beta (IL-16). and alkaline phosphatase (ALP) enzyme levels.
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Key Findings & Data:Material and method: 36 estrogen sufficient (E+) and 37 estrogen deficient women (E) were divided into two groups as chronic peri-odontitis and clinically healthy controls after clinical and radiographic examinations.
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Conclusion & Impact:A positive statistical correlation was found between total ALP levels and IL-16 levels (r=0.436, p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: The aim of this study was to determine how serum estrogen levels in postmenapousal wonien may possibly influence the gin-gival crevicular fluid (GCF) interleukin-1 beta (IL-16). and alkaline phosphatase (ALP) enzyme levels. Material and method: 36 estrogen sufficient (E+) and 37 estrogen deficient women (E) were divided into two groups as chronic peri-odontitis and clinically healthy controls after clinical and radiographic examinations. E+ group consists of 19 gingivitis (EAG) and 17 chronic periodontitis (E+P) patients and E' group consists of 20 gingivitis (EG) and 17 chronic periodontitis (ENP) patients. Periodon¬tal examinanions include; plaque (PI) and gingival (GI) indices, bleeding on probing (BOP), probing depths (PD), clinical attachment loss (CAL) measurements. Assay for GCF IL-1B and ALP were carried out by enzyme-linked immunosorbent assay (ELISA). The pa¬ired samples student t test was used to compare the ALP and IL-1B levels and clinical parameters. The correlation among all parameters were analyzed using the pearson correlation. Results: The mean of all clinical parameters (PI, GI, BOP, PD, CAL), GCF ALP and IL-16 levels were significantly higher in periodon¬titis groups (p0.05). A positive statistical correlation was found between total ALP levels and IL-16 levels (r=0.436, p

Özet

Amaç: Çalışmamızın amacı; postmenapozal dönemdeki bayanlarda serum östrojen seviyelerinin dişeti oluğu sıvısında (DOS) bulunan interlökin 1-beta (IL-1B) ve alkalen fosfataz (ALP) enzim seviyelerine olan etkisini değerlendirmektir. Gereç ve Yöntem: 36 östrojen seviyesi yeterli postmenapozal bayan (Ö+) ve 37 östrojen seviyesi yetersiz postmenapozal bayan (Ö") kli¬nik ve radyografik değerlendirmeler sonucu kronik periodontitisli ve gingivitisli olmak üzere iki alt gruba ayrıldı. Ö+ grup, 19 gingivitis (CAG) ve 17 kronik periodontitisli (Ö+P) hasta; Ö" grup, 20 gingivitis (ÖG) ve 17 kronik periodontitisli (ÖP) hastadan oluşmaktadır. Klinik periodontal değerlendirme; plak indeksi (PI), gingival indeks (GI), sondlamada kanama (SK), cep derinliği (CD) ve ataşman kay¬bı (AK) miktarı ölçümleri ile yapıldı. İL-16 ve ALP seviyeleri enzim-bağlı immunosorbent testi (ELISA) ile değerlendirildi. Klinik pa¬rametreler ve IL-1B ve ALP seviyelerinin karşılaştırmasında paired samples t testi kullanıldı. Parametreler arasındaki ilişkiler pearson korelasyon testi ile değerlendirildi. Bulgular: Periodontitisli hastalarda gingivitisli hastalara oranla tüm klinik indeks değerleri ve DOS IL-1B ve ALP seviyeleri istatistik¬sel olarak daha yüksektir (p0.05). İL-IB total seviyesi ile ALP total seviyesi arasında pozitif bir ilişki vardır (r=0.436, p

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Cite This Article

SERDAR, M., DALTABAN, Ö., SAYGUN, I., BAL, B., BALOŞ, K. (2022). Effects of serum estradiol levels on gingival crevicular fluid IL-IB and ALP levels in postmenapousal women. Gazi Üniversitesi Diş Hekimliği Fakültesi Dergisi, Cilt: 23 - Sayı: 2, 105–109. https://ajindex.com/articles/521563

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