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Journals / Gazi University Journal of Science Part A: Engineering and Innovation / 2022 / Cilt: 9 - Sayı: 3

The Effect of Nanostructured Titanium Surface on Protein Adsorption

Hasret Tolga ŞİRİN
Ebru AKDOĞAN
Pages
225–232
Publication Date
2022-10-19
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results showed that the amount of protein adsorbed on the surfaces increased significantly with increasing surface roughness and a significant change in the conformation of the adsorbed protein occurred on every surface albeit in a different fashion.

📌 3 Key Takeaways

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Objective & Hypothesis:The amount and conformation of bovine serum albumin upon adsorption on titanium (Ti) surfaces containing nanotubes with different pore sizes were investigated.
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Key Findings & Data:Results showed that the amount of protein adsorbed on the surfaces increased significantly with increasing surface roughness and a significant change in the conformation of the adsorbed protein occurred on every surface albeit in a different fashion.
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Conclusion & Impact:When anodized samples were considered, it was observed that the changes in the secondary structure seemed to be correlated with to the pore size of the nanotubes rather than the surface roughness.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Titanium Implant · Nanotube · Anodic Oxidation Protein

Abstract

The amount and conformation of bovine serum albumin upon adsorption on titanium (Ti) surfaces containing nanotubes with different pore sizes were investigated. Nanotubes were created on the surfaces via anodization. Protein adsorption behavior on anodized surfaces were compared with the adsorption behavior on smooth and sanded Ti surfaces. The conformational changes in surface adsorbed proteins were evaluated using the second derivative and curve fitting methods applied to the Fourier transform infrared spectra of the surfaces. Results showed that the amount of protein adsorbed on the surfaces increased significantly with increasing surface roughness and a significant change in the conformation of the adsorbed protein occurred on every surface albeit in a different fashion. When anodized samples were considered, it was observed that the changes in the secondary structure seemed to be correlated with to the pore size of the nanotubes rather than the surface roughness.

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Cite This Article

ŞİRİN, H. T., AKDOĞAN, E. (2022). The Effect of Nanostructured Titanium Surface on Protein Adsorption. Gazi University Journal of Science Part A: Engineering and Innovation, Cilt: 9 - Sayı: 3, 225–232. https://ajindex.com/articles/521475

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References (2)

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