Journals / Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi / 2021 / Cilt: 26 - Sayı: 3

The Importance of Hematological and Demographic Characteristics in the Course of COVID-19 Pneumonia

COVID-19 Pnömonisi Seyrinde Hematolojik ve Demografik Özelliklerin Önemi

Pages
460–467
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Findings of this study suggest that some laboratory parameters have prrognostic value in COVID-19 patients are beneficial and frequent follow-ups of selected laboratory parameters can play a key role, especially in patients with comorbidities and advanced age due to the increased risk of severity.

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: COVID-19 is a rapidly progressive viral disease and early diagnosis is important.
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Key Findings & Data:We aimed to analyze the hematological parameters that can assist in early detection of severe COVID-19 pneumonia and to determine the significance of demographic characteristics and laboratory parameters in predicting progression to severe disease in mild-to-moderate COVID-19 pneumonia.
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Conclusion & Impact:Conclusion: Findings of this study suggest that some laboratory parameters have prrognostic value in COVID-19 patients are beneficial and frequent follow-ups of selected laboratory parameters can play a key role, especially in patients with comorbidities and advanced age due to the increased risk of severity.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Introduction: COVID-19 is a rapidly progressive viral disease and early diagnosis is important. We aimed to analyze the hematological parameters that can assist in early detection of severe COVID-19 pneumonia and to determine the significance of demographic characteristics and laboratory parameters in predicting progression to severe disease in mild-to-moderate COVID-19 pneumonia. Materials and Methods: This study included 336 patients with COVID-19 pneumonia. Patients’ demographic data and laboratory findings were obtained retrospectively. The patients were divided into two groups: mild-to-moderate and severe pneumonia. Results: Of 336, 152 patients had mild-to-moderate and 184 had severe COVID-19 pneumonia. White blood cell, aspartate aminotransferase, fibrinogen, D-dimer, procalcitonin, ferritin, troponin, C-reactive protein levels, systemic inflammatory index, and absolute neutrophil (N) count, as well as N-to-lymphocyte (L), monocyte (M)-to-L, and platelet-to-L ratios were significantly higher in severe pneumonia than mild-to-moderate ones. Albumin level, absolute L and M count, and erythrocyte distribution width were significantly lower in severe pneumonia. The most common comorbidities were hypertension, diabetes, chronic obstructive pulmonary disease. Conclusion: Findings of this study suggest that some laboratory parameters have prrognostic value in COVID-19 patients are beneficial and frequent follow-ups of selected laboratory parameters can play a key role, especially in patients with comorbidities and advanced age due to the increased risk of severity.

Özet

Giriş: COVID-19 hızla gelişen viral bir hastalıktır ve erken teşhis önemlidir. Şiddetli COVID-19 pnömonisinin erken teşhisine yardımcı olabilecek hematolojik parametreleri analiz etmeyi ve hafif orta şiddette COVID-19 pnömonisinde ciddi hastalığa ilerlemeyi öngörmede demografik özelliklerin ve laboratuvar parametrelerinin önemini belirlemeyi amaçladık. Materyal ve Metod: Bu çalışmaya COVID-19 pnömonisi olan 336 hasta dahil edildi. Hastaların demografik verileri ve laboratuvar bulguları retrospektif olarak elde edildi. Hastalar hafif-orta ve şiddetli pnömoni olmak üzere iki gruba ayrıldı. Bulgular: 336 hastanın 152’sinde hafif-orta şiddetli, 184’ünde şiddetli COVID-19 pnömonisi vardı. Beyaz kan hücresi, aspartat aminotransferaz, fibrinojen, D-dimer, prokalsitonin, ferritin, troponin, C-reaktif protein seviyeleri, sistemik inflamatuar indeks ve mutlak nötrofil (N) sayısının yanı sıra N-lenfosit (L), monosit (M)-L ve trombosit-L oranları, şiddetli pnömonide hafif-orta şiddette olanlara göre anlamlı olarak daha yüksekti. Ağır pnömonide albümin düzeyi, mutlak L ve M sayısı ve eritrosit dağılım genişliği anlamlı olarak daha düşüktü. En sık eşlik eden hastalıklar hipertansiyon, diyabet, kronik obstrüktif akciğer hastalığı idi. Sonuç: Bu çalışmanın bulguları, COVID-19’da prognostik laboratuvar testlerinin faydalı olduğunu ve seçilen laboratuvar parametrelerinin sık takip edilmesinin, artan şiddet riski nedeniyle özellikle komorbiditeli ve ileri yaştaki hastalarda önemli bir rol oynayabileceğini düşündürmektedir.

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Cite This Article

GÜL, Y., TORAMAN, Z. A., ŞENOL, A., BALİN, Ş. Ö., YILDIRIM, A., GÜNDAĞ, Ö. (2022). The Importance of Hematological and Demographic Characteristics in the Course of COVID-19 Pneumonia. Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi, Cilt: 26 - Sayı: 3, 460–467. https://ajindex.com/articles/517085

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