Journals / European Journal of Breast Health / 2021 / Cilt: 17 - Sayı: 4

Stewart-Treves Syndrome: A Rare But Aggressive Complication of Breast Cancer-Related Lymphedema

Pages
92–96
Publication Date
2022-10-18
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In conclusion, STS is a rare but aggressive and important complication of BCRL.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Stewart-Treves syndrome (STS) is an angiosarcoma that usually develop in an extremity with longstanding lymphedema.
📊
Key Findings & Data:A 56-year-old woman presented with chronic lymphedema of the left arm.
💡
Conclusion & Impact:In conclusion, STS is a rare but aggressive and important complication of BCRL.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Stewart-Treves syndrome (STS) is an angiosarcoma that usually develop in an extremity with longstanding lymphedema. Most affected patients have a history of breast cancer treated with radical mastectomy. Here, we report a case of STS with breast cancer-related lymphedema (BCRL) for a period of seven years. A 56-year-old woman presented with chronic lymphedema of the left arm. Nine years previously she had modified radical mastectomy for grade 2, invasive, ductal breast cancer. Upon physical examination, a tender, purplish lesion on the medial half of the affected arm was observed. The lesion spread rapidly with different-sized, scattered, purple-colored lesions in the affected area. A prompt skin biopsy was reported as STS. An immediate arm amputation was performed. However, a few months later she presented with new lesions on the anterior thorax and subsequent local recurrence around the scar. She received radiation-therapy. However, six months later the angiosarcoma had spread to the pelvic and upper limb area with scattered skin lesions. She had several problems during the chemotherapy and radiation-therapy, although she survived beyond 20 months. In conclusion, STS is a rare but aggressive and important complication of BCRL. Awareness of rapidly progressing skin lesions and detailed investigation, as well as prompt surgery is necessary for patients with BCRL in order to relatively increase the survival time.

🔖

Cite This Article

GÖKÖZ, Ö., BORMAN, P., YAMAN, A. (2022). Stewart-Treves Syndrome: A Rare But Aggressive Complication of Breast Cancer-Related Lymphedema. European Journal of Breast Health, Cilt: 17 - Sayı: 4, 92–96. https://ajindex.com/articles/510710

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (1)

  1. Stewart FW, Treves N. Lymphangiosarcoma in postmastectomy lymphoedema: a report of six cases in elephantiasis chirurgica. Cancer 1948; 1: 64-81. (PMID: 18867440) [Crossref] Sharma A, Schwartz RA. Stewart Treves syndrome: pathogenesis and management. J Am Acad Dermatol 2012; 67: 1342-1348. (PMID: 22682884) [Crossref] Berebichez-Fridman R, Deutsch YE, Joyal TM, Molvera PB, Benedetto PW, et al. Stewart-Treves Syndrome: a case report and review of the literature. Case Rep Oncol 2016; 9: 205-211. (PMID: 27099606) [Crossref] Li B, Wang Z. Stewart-Treves syndrome: magnetic resonance imaging data compared with pathological results from a single center. Oncol Lett 2018; 15: 1113-1118. (PMID: 29391898) [Crossref] Farzaliyev F, Hamacher R, Steinau HU, Bertram S, Podleska LE. Secondary angiosarcoma: a fatal complication of chronic lymphedema. J Surg Oncol 2020; 121: 85-90. (PMID: 31236970) [Crossref] Lee R, Saardi KM, Schwartz RA. Lymphedema related angiogenic tumors and other malignancies. Clin Dermatol 2014; 32: 616-620. (PMID: 25160102) [Crossref] Cui L, Zhang J, Zhang X, Chang H, Qu C, Zhang J, et al. Angiosarcoma (Stewart-Treves syndrome)in postmastectomy patients: report of 10 cases and review of the literature. Int J Clin Exp Pathol 2015; 8: 11108-11115. (PMID: 26617830) [Crossref] Tabareau-Delalande F, de Muret A, Miquelestorena-Standley E, Decouvelaere AV, de Pinieux G. Cutaneous epitheloid clear cells angiosarcoma in a young woman with congenital lymphedema. Case Rep Pathol 2013; 2013: 931973. (PMID: 24078891) [Crossref] Cabral ANF, Rocha RH, Amaral ACVD, Medeiros KB, Nogueira PSE, Diniz LM. Cutaneous angiosarcoma: report of three different and typical cases admitted in a unique dermatology clinic. An Bras Dermatol 2017; 92: 235-238. (PMID: 28538886) [Crossref] Taşdemir A, Karaman H, Ünal D, Mutlu H. Stewart-Treves Syndrome after bilateral mastectomy and radiotherapy for breast carcinoma: Case report. J Breast Health 2015; 11: 92-94. (PMID: 28331699) [Crossref] Felmerer G, Dowlatshahi AS, Stark GB, Földi E, Földi M, Ahls MG, et al. Lymphangiosarcoma: is Stewart-Treves Syndrome a preventable condition? Lymphat Res Biol 2016; 14: 35-39. (PMID: 26584023) [Crossref] Alan S, Aktas H, Ersoy ÖF, Aktümen A, Erol H. Stewart-Treves syndrome in a woman with mastectomy. J Clin Diagn Res 2016; 10: WD01-WD02. (PMID: 27042566) [Crossref] Wang LL, Cui LF, Gao Y, Jiang ZC. Clinicopathologic features of StewartTreves syndrome. Int J Clin Exp Pathol 2019; 12: 680-688. (PMID: