To the best of our knowledge, this is the first case report revealing the association of CRPS with hyperplasia of Pacinian corpuscles.
📌 3 Key Takeaways
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Objective & Hypothesis:Pacinian disorders are exceedingly rare, and the exact pathogenesis is still unknown.
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Key Findings & Data:In this case report, we present the case of a 49-year-old male with Pacinian corpuscle hyperplasia located on the metacarpophalangeal joint, emerging at the same hand of the patient two years after the treatment due to complex regional pain syndrome (CRPS).
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Conclusion & Impact:To the best of our knowledge, this is the first case report revealing the association of CRPS with hyperplasia of Pacinian corpuscles.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Abstract
Pacinian disorders are exceedingly rare, and the exact pathogenesis is still unknown. The most common symptoms are pain, sensory changes, and a visible or palpable mass, and diagnosis is usually made by pathological examination after the excision of the painful nodule. In this case report, we present the case of a 49-year-old male with Pacinian corpuscle hyperplasia located on the metacarpophalangeal joint, emerging at the same hand of the patient two years after the treatment due to complex regional pain syndrome (CRPS). To the best of our knowledge, this is the first case report revealing the association of CRPS with hyperplasia of Pacinian corpuscles.
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Cite This Article
AKSU, A. E., GÖKÖZ, Ö., KAPLAN, G. O., ÖZDEMİR, F. D. M. (2022). First case report of Pacinian corpuscle hyperplasia following complex regional pain syndrome. Joint diseases and related surgery, Cilt: 33 - Sayı: 1, 249–252. https://ajindex.com/articles/559169
Schuler FA 3rd, Adamson JE. Pacinian neuroma, an unusual cause of finger pain. Plast Reconstr Surg 1978;62:576-9
Imai S, Kikuchi K, Matsusue Y. Digital pacinian corpuscle hyperplasia. Journal of the American Society for Surgery of the Hand 2003;3:175-80
Prichard RW, Custer RP. Pacinian neurofibroma. Cancer 1952;5:297-301
Fassola I, Wenzke L, Ertel W, Krasnici S. Pacinian neuromas and neurofibromas of the hands and fingers: A systematic review. J Hand Surg Eur Vol 2019;44:925-31
Atik OŞ. What are the expectations of an editor from a scientific article? Jt Dis Relat Surg 2020;31:597-8
Miller SH, Rusenas I. Changes in primate Pacinian corpuscles following volar pad excision and skin grafting. A preliminary report. Plast Reconstr Surg 1976;57:627-36
Bell J, Bolanowski S, Holmes MH. The structure and function of Pacinian corpuscles: A review. Prog Neurobiol 1994;42:79-128
Narayanamurthy V, Winston AT, Gupta A. A rare case of Pacinian corpuscle neuroma. Can J Plast Surg 2005;13:43-5
Stark B, Carlstedt T, Hallin RG, Risling M. Distribution of human Pacinian corpuscles in the hand. A cadaver study. J Hand Surg Br 1998;23:370-2
Rhode CM, Jennings WD Jr. Pacinian corpuscle neuroma of digital nerves. South Med J 1975;68:86-9
Soua Y, Belhareth K, Akkari H, Jguirim M, Belhadjali H, Abdeljelil NB, et al. Digital pacinian neuroma in a patient with myeloma. Our Dermatol Online 2020;11:171-3
Pickrell BB, Talbot SG, Costigan DC, Sampson CE. Pacinian hyperplasia presenting with Raynaud's phenomenon. Case Reports Plast Surg Hand Surg 2019;6:148-52
Friedrich RE, Hagel C. Painful Vater-Pacini neuroma of the digit in neurofibromatosis type 1. GMS Interdiscip Plast Reconstr Surg DGPW 2019;8:Doc03
Calder JS, Holten I, Terenghi G, Smith RW. Digital nerve compression by hyperplastic Pacinian corpuscles. A case report and immunohistochemical study. J Hand Surg Br 1995;20:218-21
Iyengar S, Ossipov MH, Johnson KW. The role of calcitonin gene-related peptide in peripheral and central pain mechanisms including migraine. Pain 2017;158:543-59
Hart WR, Thompson NW, Hildreth DH, Abell MR. Hyperplastic pacinian corpuscles: A cause of digital pain. Surgery 1971;70:730-5
Zanardi F, Cooke RM, Maiorana A, Curti S, Farioli A, Bonfiglioli R, et al. “Is this case of a very rare disease workrelated?” A review of reported cases of Pacinian neuroma. Scand J Work Environ Health 2011;37:253-8