Journals / European Archives of Medical Research / 2019 / Cilt: 35 - Sayı: 1

Clinical Results of Platelet-Rich Plasma Injection in the Treatment of Androgenetic Alopecia

Pages
33–37
Publication Date
2022-10-12
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The mean VAS value decreased from6.8 to 2.1 after the procedure.Discussion: PRP injections, which are prepared in a simple way without using a commercial kit, are an effective treatment option in alopeciatreatment with high patient satisfaction and low cost.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Introduction: Platelet-rich plasma (PRP) represents a small volume of plasma in which the platelet concentration in normal blood is increased tooptimum values.
📊
Key Findings & Data:In this study, we aimed to evaluate the efficacy of adjuvant therapyin patients with male and female alopecia by establishing a standard protocol for the preparation and application of PRP.Methods: Fifteen patients with mild to moderate androgenetic alopecia (Ludwig alopecia score I-II for women and Hamilton-Norwood score 1-4 formen) who had not received topical or systemic treatment for alopecia in the last 6 months were included in the study.
💡
Conclusion & Impact:The mean VAS value decreased from6.8 to 2.1 after the procedure.Discussion: PRP injections, which are prepared in a simple way without using a commercial kit, are an effective treatment option in alopeciatreatment with high patient satisfaction and low cost.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Introduction: Platelet-rich plasma (PRP) represents a small volume of plasma in which the platelet concentration in normal blood is increased tooptimum values. Its effect depends on the growth factors released from platelets. Although it has been investigated and used in many areas of plasticsurgery, PRP injection has recently attracted interest in the treatment of hair loss. In this study, we aimed to evaluate the efficacy of adjuvant therapyin patients with male and female alopecia by establishing a standard protocol for the preparation and application of PRP.Methods: Fifteen patients with mild to moderate androgenetic alopecia (Ludwig alopecia score I-II for women and Hamilton-Norwood score 1-4 formen) who had not received topical or systemic treatment for alopecia in the last 6 months were included in the study. Eleven of the patients weremale and 4 were female. The mean age was 41 years (27-55). PRP was prepared using a single spin method with high acceleration force and lowcentrifugation time, and three sessions were performed with an interval of 3-4 weeks. Patient satisfaction was assessed by visual analogue scale (VAS).The assessments on day 0, 1st month, 2nd month and 6th month were evaluated retrospectively.Results: Hair pull test was positive in all patients (100%) before the treatment and the mean number of hair loss was 6.7. After the third treatmentsession, the hair pull test was negative in 13 patients (86.6%) with a mean of number of 2.5 hair loss. An improvement in hair density and qualitywas demonstrated with macroscopic photographs taken in a standard manner before and after the procedure. The mean VAS value decreased from6.8 to 2.1 after the procedure.Discussion: PRP injections, which are prepared in a simple way without using a commercial kit, are an effective treatment option in alopeciatreatment with high patient satisfaction and low cost.

🔖

Cite This Article

ÖZER, K., ÇOLAK, Ö. (2022). Clinical Results of Platelet-Rich Plasma Injection in the Treatment of Androgenetic Alopecia. European Archives of Medical Research, Cilt: 35 - Sayı: 1, 33–37. https://ajindex.com/articles/510435

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (13)

  1. Garg S, Manchanda S. Platelet-rich plasma-an ‘Elixir’ for treatment of alopecia: personal experience on 117 patients with review of literature. Stem Cell Investig 2017;4:64
  2. Starace M, Alessandrini A, D’Acunto C, Melandri D, Bruni F, Patrizi A, et al. Platelet-rich plasma on female androgenetic alopecia: Tested on 10 patients. J Cosmet Dermatol 2019;18:59-64
  3. Ayatollahi A, Hosseini H, Shahdi M, AhmadNasrollahi S, NassiriKashani M, Yadangi S, et al. Platelet-rich Plasma by Single Spin Process in Male Pattern Androgenetic Alopecia: Is it an Effective Treatment? Indian Dermatol Online J 2017;8:460-4
  4. Gkini MA, Kouskoukis AE, Tripsianis G, Rigopoulos D, Kouskoukis K. Study of Platelet-Rich Plasma Injections in the Treatment of Androgenetic Alopecia Through an One-Year Period. J Cutan Aesthet Surg 2014;7:213-9
  5. Ferrando J, García-García SC, González-de-Cossío AC, Bou L, Navarra E. A Proposal of an Effective Platelet-rich Plasma Protocol for the Treatment of Androgenetic Alopecia. Int J Trichology 2017;9:165-70
  6. Khatu SS, More YE, Gokhale NR, Chavhan DC, Bendsure N. Platelet-Rich Plasma in Androgenic Alopecia: Myth or an Effective Tool. J Cutan Aesthet Surg 2014;7:107-10
  7. Gentile P, Garcovich S, Bielli A, Scioli MG, Orlandi A, Cervelli V. The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial. Stem Cells Transl Med 2015;4:1317-23
  8. Torkamani N, Rufaut NW, Jones L, Sinclair R. Destruction of the arrector pili muscle and fat infiltration in androgenic alopecia. Br J Dermatol 2014;170:1291-8
  9. Yazdabadi A, Whiting D, Rufaut NW, Sinclair R. Miniaturized hairs maintain contact with the arrector pili muscle in alopecia areata but not in androgenetic alopecia: A model for reversible miniaturization and potential for hair regrowth. Int J Trichology 2012;4:154-7
  10. Torkamani N, Rufaut NW, Jones L, Sinclair RD. Beyond goosebumps: Does the arrector pili muscle have a role in hair loss? Int J Trichology 2014;6;88-94
  11. Dohan Ehrenfest DM, Rasmusson L, Albrektsson T. Classification of platelet concentrates: From pure platelet-rich plasma (P-PRP) to leucocyte- and platelet-rich fibrin (L-PRF) Trends Biotechnol 2009; 27:158-67
  12. Li ZJ, Choi HI, Choi DK, Sohn KC, Im M, Seo YJ, et al. Autologous platelet-rich plasma: A potential therapeutic tool for promoting hair growth. Dermatol Surg 2012;38:1040-6
  13. Jha AK, Udayan UK, Roy PK, Amar AKJ, Chaudhary RKP. Original article: Platelet-rich plasma with microneedlin