Journals / European Archives of Medical Research / 2020 / Cilt: 36 - Sayı: 1

The Correlation of Carbon Monoxide Level, Lactate, Creatine Kinase Myocardial Band, Troponin T, Magnetic Resonance Imaging and Clinical Results in Acute Carbon Monoxide Poisoning

Pages
12–16
Publication Date
2022-11-06
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Radiological evaluation should be used for excluding the reasons for a neurological disorder, not for diagnostic reasons.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: In this study, it was aimed to investigate the correlation between arrival-carboxyl hemoglobin (COHb) levels, lactate, creatine kinase-myocardial band (CK-MB), troponin T and radiological findings in patients who were admitted to emergency service with a pre-diagnosis of carbon monoxide (CO) poisoning between the years 2014-2016.
📊
Key Findings & Data:Methods: The patients who were admitted to emergency service with a pre-diagnosis of CO poisoning between the years 2014-2016 were screened retrospectively.
💡
Conclusion & Impact:Radiological evaluation should be used for excluding the reasons for a neurological disorder, not for diagnostic reasons.
🔬Design:Research Article
📍Scope:2014-2016 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: In this study, it was aimed to investigate the correlation between arrival-carboxyl hemoglobin (COHb) levels, lactate, creatine kinase-myocardial band (CK-MB), troponin T and radiological findings in patients who were admitted to emergency service with a pre-diagnosis of carbon monoxide (CO) poisoning between the years 2014-2016. Methods: The patients who were admitted to emergency service with a pre-diagnosis of CO poisoning between the years 2014-2016 were screened retrospectively. Demographic data, arrival-COHb levels, lactate, CK-MB, troponin T, and if available, computed tomography or magnetic resonance (MR) imaging of the patients, their clinical treatment, and results were compared. Results: While COHb values of the patients at emergency department arrival were 14.536±13.047%, they were found as 4.536±3.698% at discharge from the hospital. A correlation was not observed statistically between arrival-COHb, lactate, troponin T, and CK-MB. Arrival-lactate level was found as >2.1 mmol/L in 47 patients (36.90%). Cranial MR findings that suggest CO poisoning were determined in four cases who underwent hyperbaric oxygen treatment; millimetric signal enhancements being concordant with chronic microangiopathic ischemic gliotic foci in white matter were determined in the level of the periventricular field, bilateral corona radiata and centrum semiovale in MRI.Conclusion: There is no correlation between arrival-COHb levels of the patients and lactate, CK-MB and troponin T in CO poisoning. Radiological evaluation should be used for excluding the reasons for a neurological disorder, not for diagnostic reasons.

🔖

Cite This Article

İNCEKAYA, Y., MINGIR, T., TURGUT, N., ALTINTEPE, N., AYVACI, B., GÜN, İ., DAĞLI, E., KARACALAR, S., FEYİZİ, H., ÖNOL, S. D. (2022). The Correlation of Carbon Monoxide Level, Lactate, Creatine Kinase Myocardial Band, Troponin T, Magnetic Resonance Imaging and Clinical Results in Acute Carbon Monoxide Poisoning. European Archives of Medical Research, Cilt: 36 - Sayı: 1, 12–16. https://ajindex.com/articles/650416

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (13)

  1. Huysal K, Budak YU, Aydin U, Demirci H, Turk T, Karadag M. COHb Level and High-Sensitivity Cardiac Troponin T in 2012 in Bursa, Turkey: A Retrospective Single-Center Study. Iran Red Crescent Med J 2016;18:e27061
  2. Lang E, Qadri SM, Jilani K, Zelenak C, Lupescu A, Schleicher E, et al. Carbon monoxide-sensitive apoptotic death of erythrocytes. Basic Clin Pharmacol Toxicol 2012;111:348-55
  3. Moon JM, Shin HM, Chun JB. The value of initial lactate in patients with carbon monoxide intoxication: in the emergency department. Hum Exp Toxicol 2011;30:836-43
  4. T.C. Ministry of Health Turkish Public Health Authority (Environmental Health Department) Turkey Carbon Monoxide Poisoning Prevention Program and Action Plan (2015-2018). 1st Edition: Anıl Press. Kızılay / Ankara Available from: URL: http:/ www.cevresagligi.thsk.saglik.gov.tr 5. Onodera M, Fujino Y, Kikuchi S, Sato M, Mori K, Beppu T, et al. Utility of the Measurement of Carboxyhemoglobin Level at the Site of Acute Carbon Monoxide Poisoning in Rural Areas. Scientifica (Cairo) 2016;2016:6192369
  5. Bozeman WP, Myers RAM, Barish RA. Confirmation of the pulse oximetry gap in carbon monoxide poisoning. Ann Emerg Med 1997;30:608-11
  6. Bahcebasi T, Kandis H, Baltaci D, Kara IH. Factors affecting exhaled carbon monoxide levels in coffeehouses in the Western Black Sea region of Turkey. Toxicol Ind Health 2011;27:195-204
  7. Choi IS. Carbon monoxide poisoning: systemic manifestations and complications. J Kor Med Sci 2001;16:253-61
  8. Bernas S, Rzepeck J, Winnicka R, Kołaciński Z, Krakowiak A. Acute poisonings with carbon monoxide among the patients hospitalized in the Toxicology Unit during the period of 2006-2010. Przegl Lek 2012;69:415-9
  9. Ozyurt A, Karpuz D, Yucel A, Tosun MD, Kibar AE, Hallioglu O. Effects of Acute Carbon Monoxide Poisoning on ECG and Echocardiographic Parameters in Children. Cardiovasc Toxicol 2017;17:326-34
  10. Doğan NÖ, Savrun A, Levent S, Günaydın GP, Çelik GK, Akküçük H, et al. Can initial lactate levels predict the severity of unintentional carbon monoxide poisoning? Hum Exp Toxicol 2015;34:324-9
  11. Repplinger DJ, Slomer A, Nolan B, Su MK. Lactate and carbon monoxide poisoning: More questions regarding its prognostic role. Hum Exp Toxicol 2016;35:794
  12. Buckley NA, Juurlink DN, Isbister G, Bennett MH, Lavonas EJ. Hyperbaric oxygen for carbon monoxide poisoning. Cochrane Database Syst Rev 2011;CD002041
  13. Kandiş H, Katırcı Y, Çakır Z, Aslan Ş, Uzkeser M, Bilir Ö. A Retrospe