Journals / European Archives of Medical Research / 2021 / Cilt: 37 - Sayı: 1

Thyroid Cancer Prevalence and Risk in Incidental Thyroid Lesions Detected with 18F-FDG PET/CT

Pages
32–37
Publication Date
2022-10-12
DOI
—
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⚡ TL;DR(Too Long; Didn't Read)

According to the results obtained from these values, the relationship between thyroid nodules and thyroidcancer was analyzed.Results: Among the group of 50 patients, 18F-FDG PET/CT scanning detected all as having thyroid nodules.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The aim of this study is to analyze the relationship between thyroid nodules detected in patients who were examined in our clinicfor any indication and had 18fluoro-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) scanningand thyroid cancer.Methods: Results of patients who had FDG PET/CT scanning for any indication other than thyroid cancer during 2015 and 2016 in OkmeydaniTraining and Research Hospital were examined.
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Key Findings & Data:According to the results obtained from these values, the relationship between thyroid nodules and thyroidcancer was analyzed.Results: Among the group of 50 patients, 18F-FDG PET/CT scanning detected all as having thyroid nodules.
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Conclusion & Impact:Since nosignificant results were obtained between the SUVmax and malignancy, no threshold value for SUVmax was calculated.
🔬Design:Research Article
📍Scope:2015 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: The aim of this study is to analyze the relationship between thyroid nodules detected in patients who were examined in our clinicfor any indication and had 18fluoro-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) scanningand thyroid cancer.Methods: Results of patients who had FDG PET/CT scanning for any indication other than thyroid cancer during 2015 and 2016 in OkmeydaniTraining and Research Hospital were examined. Age and genders of patients, FDG PET scanning indications, FDG accumulation type (focalor diffuse), lesion maximum standard uptake value (SUVmax), histology, and pathology of the patient who had fine-needle aspiration biopsy(FNAB) or surgery were recorded. According to the results obtained from these values, the relationship between thyroid nodules and thyroidcancer was analyzed.Results: Among the group of 50 patients, 18F-FDG PET/CT scanning detected all as having thyroid nodules. Forty cases had benign diagnoses,whereas ten cases had malignant diagnoses either by FNAB or total thyroidectomy. According to the diagnosis results, the SUVmax averageof the malignant group was higher than the SUVmax average of the benign group. However, no statistically significant result was obtained(p>0.05). The results also showed no statistically significant association regarding tumor size between the malignant and benign groups(p>0.05).Conclusion: Thyroid incidentaloma was detected among patients who had 18F-FDG PET/CT scanning for any reason other than thyroid cancer.Thyroid malignancy was detected in 20% of patients diagnosed with thyroid nodules by with focal 18F-FDG accumulation. No statisticallysignificant results concerning SUVmax value and lesion size were obtained among groups having benign and malignant diagnoses. Since nosignificant results were obtained between the SUVmax and malignancy, no threshold value for SUVmax was calculated.

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Cite This Article

KARYAĞAR, S. S., ÖZÜLKER, F., ÖZÜLKER, T., CERAN, İ. F. (2022). Thyroid Cancer Prevalence and Risk in Incidental Thyroid Lesions Detected with 18F-FDG PET/CT. European Archives of Medical Research, Cilt: 37 - Sayı: 1, 32–37. https://ajindex.com/articles/510307

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References (14)

  1. Jin J, Wilhelm SM, McHenry CR. Incidental thyroid nodule: patterns of diagnosis and rate of malignancy. Am J Surg 2009;197:320-4
  2. Yasuda S, Ide M, Fujii H, Nakahara T, Mochizuki Y, Takahashi W, et al. Application of positron emission tomography imaging to cancer screening. Br J Cancer 2000;83:1607-11
  3. Choi JY, Lee KS, Kim HJ, Shim YM, Kwon OJ, Park K, et al. Focal thyroid lesions incidentally identified by integrated 18F-FDG PET/CT: clinical significance and improved characterization. J Nucl Med 2006;47:609- 15
  4. Soelberg KK, Bonnema SJ, Brix TH, Hegedüs L. Risk of malignancy in thyroid incidentalomas detected by 18F-fluorodeoxyglucose positron emission tomography: a systematic review. Thyroid 2012;22:918-25
  5. Kwak JY, Kim EK, Yun M, Cho A, Kim MJ, Son EJ, et al. Thyroid incidentalomas identified by 18F-FDG PET: sonographic correlation. AJR Am J Roentgenol 2008;191:598-603
  6. Chen W, Parsons M, Torigian DA, Zhuang H, Alavi A. Evaluation of thyroid FDG uptake incidentally identified on FDG-PET/CT imaging. Nucl Med Commun 2009;30:240-4
  7. Bae JS, Chae BJ, Park WC, Kim JS, Kim SH, Jung SS, et al. Incidental thyroid lesions detected by FDG-PET/CT: prevalence and risk of thyroid cancer. World J Surg Oncol 2009;7:63
  8. Shie P, Cardarelli R, Sprawls K, Fulda KG, Taur A. Systematic review: prevalence of malignant incidental thyroid nodules identified on fluorine-18 fluorodeoxyglucose positron emission tomography. Nucl Med Commun 2009;30:742-8
  9. Brander A, Viikinkoski P, Nickels J, Kivisaari L. Thyroid gland: US screening in a random adult population. Radiology 1991;181:683-7
  10. Youserm DM, Huang T, Loevner LA, Langlotz CP. Clinical and economic impact of incidental thyroid lesions found with CT and MR. AJNR Am J Neuroradiol 1997;18:1423-8
  11. Mortensen JD, Woolner LB, Bennett WA. Gross and microscopic findings in clinically normal thyroid glands. J Clin Endocrinol Metab 1955;15:1270-80
  12. Makis W, Ciarallo A. Thyroid Incidentalomas on 18F-FDG PET/CT: Clinical Significance and Controversies. Mol Imaging Radionucl Ther 2017;26:93-100
  13. American Thyroid Association (ATA) Guidelines Taskforce on Thyroid Nodules and Differentiated Thyroid Cancer, Cooper DS, Doherty GM, Haugen BR, Kloos RT, Lee SL, et al. Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer. Thyroid 2009;19:1167-214
  14. Nam SY, Roh JL, Kim JS, Lee JH, Choi SH, Kim SY. Focal uptake of (18) F-fluorodeoxygl