AI Summary & Key Takeaways
AI InsightIn group N, nitroglycerine was administered at a dose of 0.5-2 μg/kg/min.Results: During the hypotensive period, systolic arterial pressure, di- astolic arterial pressure, mean arterial pressure, and heart rate were decreased 24%, 33%, 27% and 35%, respectively, in group E (p
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Abstract
Objective: The aim of this study was to compare esmolol to nitroglycerine in terms of effectiveness in controlling hypotension duringnasal surgery.Materials and Methods: After approval by our institutional EthicsCommittee, 40 patients were recruited and randomized into twodrug groups: esmolol (Group E) and nitroglycerine (Group N). Ingroup E, a bolus dose of 500 μg/kg esmolol was administered over30 sec followed by continuous administration at a dose of 25-300 μg/ kg/min to maintain systolic arterial pressure at 80 mmHg. In group N, nitroglycerine was administered at a dose of 0.5-2 μg/kg/min.Results: During the hypotensive period, systolic arterial pressure, di- astolic arterial pressure, mean arterial pressure, and heart rate were decreased 24%, 33%, 27% and 35%, respectively, in group E (p
Özet
Amaç: Çalışmamızın amacı nazal cerrahide esmolol ve nitrogliserininkontrollü hipotansiyon oluşturmadaki etkinliklerinin karşılaştırılma- sıdır. Gereç ve Yöntem: Etik kurul onayı alındıktan sonra 40 olgu rando- mize olarak, esmolol (Grup E) veya nitrogliserin (Grup N) şeklinde iki gruba ayrıldı. Grup E’de esmolol 30 sn içinde 500 μg/kg bolus dozverilerek idamede 25-300 μg/kg/dk ve Grup N’de nitrogliserin 0.5-2 μg/kg/dk infüzyon hızında sistolik arter basıncı 80 mmHg olacak şe-kilde uygulandı. Bulgular: Hipotansif dönemde sistolik arter basıncı, diastolik arter basıncı, ortalama arter basıncı ve kalp atım hızı değerlerinde Grup E’de %24, %33, %27 ve %35 (p