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Journals / Eurasian Journal of Medical Investigation / 2019 / Cilt: 3 - Sayı: 3

Frequency of Hypersensitivity Reactions to Chemotherapeutic Agents in Children with Cancer

Osman ÖZTÜRK
Fazıl ORHAN
Pages
214–218
Publication Date
2022-10-12
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Of the 61 patients followed during the study with thediagnosis of cancer, 8 developed hypersensitivity reaction.Results: It has been determined that the frequency of immediate hypersensitivity reactions against chemotherapeutic drugs was quite low and severe, life-threatening type anaphylactic reactions were not present.Conclusion: We found in the study group that the frequency of immediate hypersensitivity reactions to chemotherapeutic drugs was very low and no life-threatening severe anaphylactic reactions were found.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: The aim of our study is to identify the frequency and the types of immediate hypersensitivity reactionsthat might be encountered during chemotherapy usage as well as which chemotherapeutics carry more risk of causing immediate hypersensitiviy reactions, to make the expactations of the units that perform chemotherapies moreconcrete for at least immediate hypersensitivity reactions and the precautions to be taken.Methods: Sixty one patients with cancer who were hospitalised and treated in the pediatric oncology clinic.
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Key Findings & Data:Thenumber of total chemotherapeutic drug dosage, the number of total dosage for each chemotherapeutic drug, thenumber of total hypersensitivity reactions, the number of reactions against each chemotherapeutic agent,the frequency of common hypersensitivity reaction and the frequency of hypersensitivity reaction for each chemotherapeutic agent were calculated.A total of 61 patients were followed.
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Conclusion & Impact:Of the 61 patients followed during the study with thediagnosis of cancer, 8 developed hypersensitivity reaction.Results: It has been determined that the frequency of immediate hypersensitivity reactions against chemotherapeutic drugs was quite low and severe, life-threatening type anaphylactic reactions were not present.Conclusion: We found in the study group that the frequency of immediate hypersensitivity reactions to chemotherapeutic drugs was very low and no life-threatening severe anaphylactic reactions were found.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: The aim of our study is to identify the frequency and the types of immediate hypersensitivity reactionsthat might be encountered during chemotherapy usage as well as which chemotherapeutics carry more risk of causing immediate hypersensitiviy reactions, to make the expactations of the units that perform chemotherapies moreconcrete for at least immediate hypersensitivity reactions and the precautions to be taken.Methods: Sixty one patients with cancer who were hospitalised and treated in the pediatric oncology clinic. Thenumber of total chemotherapeutic drug dosage, the number of total dosage for each chemotherapeutic drug, thenumber of total hypersensitivity reactions, the number of reactions against each chemotherapeutic agent,the frequency of common hypersensitivity reaction and the frequency of hypersensitivity reaction for each chemotherapeutic agent were calculated.A total of 61 patients were followed. During the study period, 9 of 1992 chemotherapeutic dosages have beendetermined to cause immediate hypersensitivity reactions. Of the 61 patients followed during the study with thediagnosis of cancer, 8 developed hypersensitivity reaction.Results: It has been determined that the frequency of immediate hypersensitivity reactions against chemotherapeutic drugs was quite low and severe, life-threatening type anaphylactic reactions were not present.Conclusion: We found in the study group that the frequency of immediate hypersensitivity reactions to chemotherapeutic drugs was very low and no life-threatening severe anaphylactic reactions were found.

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Cite This Article

ÖZTÜRK, O., ORHAN, F. (2022). Frequency of Hypersensitivity Reactions to Chemotherapeutic Agents in Children with Cancer. Eurasian Journal of Medical Investigation, Cilt: 3 - Sayı: 3, 214–218. https://ajindex.com/articles/508721

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References (1)

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