The Effect of Body Mass Index on Postoperative Bleeding and Blood Transfusion in Patients with Coronary Bypass Surgery

Also in patients with low and normal weight compared to the obesegroup more blood loss was observed (7.12±1.87 ml/kg, p=0.017).Conclusion: In our study, in accordance with the general opinion of previous studies, we found that patients with highBMI had lower postoperative blood loss and blood use than patients with low BMI.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: The use of blood and blood products, which is a major complication, significantly increases the durationof stay in intensive care and hospitalization, as well as hospital costs on open heart surgery.

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Key Findings & Data:In our study, we aimed toinvestigate the relationship between postoperative early bleeding, blood and blood product use in coronary arterybypass grafting (CABG) surgery under cardiopulmonary bypass (CPB).Methods: In this study, 843 patients who underwent consecutive CABG operation between May 2012 and March2014 were included.

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Conclusion & Impact:Also in patients with low and normal weight compared to the obesegroup more blood loss was observed (7.12±1.87 ml/kg, p=0.017).Conclusion: In our study, in accordance with the general opinion of previous studies, we found that patients with highBMI had lower postoperative blood loss and blood use than patients with low BMI.

🔬Design:Research Article

📍Scope:2012 Verileri

⚙️Variables:Domain Parameters

Abstract

Objectives: The use of blood and blood products, which is a major complication, significantly increases the durationof stay in intensive care and hospitalization, as well as hospital costs on open heart surgery. In our study, we aimed toinvestigate the relationship between postoperative early bleeding, blood and blood product use in coronary arterybypass grafting (CABG) surgery under cardiopulmonary bypass (CPB).Methods: In this study, 843 patients who underwent consecutive CABG operation between May 2012 and March2014 were included. The patients were classified into three categories according to their body mass index (BMI); weakgroup (BMI ≤19 kg/m2), normal weight group (BMI 20-29 kg/m2) and obese group (BMI ≥30 kg/m2). Preoperatively; age,gender, height, weight, diabetes mellitus (DM), hypertension, hyperlipidemia, chronic obstructive pulmonary disease(COPD), preoperative myocardial infarction, left ventricular ejection fraction (LVEF), mean hemoglobin and platelet values, Intraoperatively; cross clamp time, cardiopulmonary bypass time, total duration of the operation, amount of cardioplegia given, number of grafts used in coronary bypass. Postoperatively; the total amount of blood used, drainageamount, given vasopressor treatment, given positive inotropic support, intraaortic balloon pump usage, intubationduration, intensive care stay, hospital stay, bleeding-related re-exploration and mortality of all patients were examined.Results: It was observed that more blood transfusions performed in patients with low and normal weight comparedto the obese group (11.22±2.85 ml/kg, p=0.011). Also in patients with low and normal weight compared to the obesegroup more blood loss was observed (7.12±1.87 ml/kg, p=0.017).Conclusion: In our study, in accordance with the general opinion of previous studies, we found that patients with highBMI had lower postoperative blood loss and blood use than patients with low BMI.

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Cite This Article

KOÇ, M., MUNGAN, U., KARTAL, H., DEMİRDAŞ, E., SiİCİM, H., EROL, G., HACİZADE, E., DEMİRKIRAN, T., COMAKLİ, H., GUNAY, C., OZ, B. S. (2022). The Effect of Body Mass Index on Postoperative Bleeding and Blood Transfusion in Patients with Coronary Bypass Surgery. Eurasian Journal of Medical Investigation, Cilt: 4 - Sayı: 1, 51–55. https://ajindex.com/articles/508682

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Finucane, M. M., Stevens, G. A., Cowan, M. J., Danaei, G., Lin, J. K., Paciorek, C. J.,. & Farzadfar, F. National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9· 1 million participants. The Lancet 2011;377:557–567. Table 3. Postoperative data of patients Variable Underweight Normal weight Obese p (BMI ≤19 kg/m2 ) (BMI 20–29 kg/m2 ) (BMI ≥30 kg/m2 ) n=76 n=408 n=359 Total RBC transfusion (mL/kg) 11.22±2.85 8.65±1.41¶ 6.56±1.05¶ 0.011 Total blood loss (mL/kg) 7.12±1.87 4.26±1.38¶ 3.23±1.15¶x 0.017 Vasopressor therapy (epinephrine, norepinephrine) 5 73 127 0.006 Positive inotropic support (dopamine) 9 92 134 0.019 Intra-aortic balloon pump 1 3 5 0.029 Ventilation time (h) 6.3±1.7 7.6±1.9 10.4±3.2 0.017 Length of ICU stay (day) 2.1±0.9 2.2±1.1 2.4±1.5 0.632 Length of hospital stay (day) 4.9±2.1 5.2±2.4 5.7±2.9 0.764 Re-exploration for bleeding or tamponade (n/%) 5/6.5 3/0.73 1/0.27 0.032 Mortality 1 0 2 0.056 ¶ Indicating a difference on comparison with BMI: 3. Koch, C. G., Li, L., Duncan, A. I., Mihaljevic, T., Loop, F. D., Starr, N. J., & Blackstone, E. H. (2006). Transfusion in coronary artery bypass grafting is associated with reduced long-term survival. The Annals of thoracic surgery 2006;81:1650–1657
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