Comparison of laboratory data of the patients is given inthe table, only significant difference was observed in terms of monocyte count and MHR (p
📌 3 Key Takeaways
🎯
Objective & Hypothesis:Objectives: In this study, we aimed to show whether high monocyte/HDL ratio (MHR), which is an important marker ofinflammation, predicts atrial fibrillation after coronary artery bypass surgery.Methods: A total of 1980 patients with preoperative sinus rhythm who underwent CABG operation between May 2012and March 2014; 256 patients who developed POAF and 256 patients who did not develop POAF in the same periodwere included in the study.
📊
Key Findings & Data:Retrospective demographic data, laboratory findings, mortality and morbidity records werecompared.Results: In this study, 256 patients were included in each group.
💡
Conclusion & Impact:Comparison of laboratory data of the patients is given inthe table, only significant difference was observed in terms of monocyte count and MHR (p
🔬Design:Research Article
📍Scope:2014 Verileri
⚙️Variables:Domain Parameters
Abstract
Objectives: In this study, we aimed to show whether high monocyte/HDL ratio (MHR), which is an important marker ofinflammation, predicts atrial fibrillation after coronary artery bypass surgery.Methods: A total of 1980 patients with preoperative sinus rhythm who underwent CABG operation between May 2012and March 2014; 256 patients who developed POAF and 256 patients who did not develop POAF in the same periodwere included in the study. Retrospective demographic data, laboratory findings, mortality and morbidity records werecompared.Results: In this study, 256 patients were included in each group. The patients with POAF were similar to those withoutPOAF in terms of preoperative and operative characteristics. Comparison of laboratory data of the patients is given inthe table, only significant difference was observed in terms of monocyte count and MHR (p
🔖
Cite This Article
BOLCAL, C., MUNGAN, U., KARTAL, H., EROL, G., DEMİRDAS, E., SİCİM, H., ARSLAN, G. (2022). Association of Monocyte-to-HDL Ratio With Postoperative Atrial Fibrillation After Coronary Artery Bypass Surgery. Eurasian Journal of Medical Investigation, Cilt: 4 - Sayı: 1, 61–65. https://ajindex.com/articles/508627
Zoni-Berisso M, Lercari F, Carazza T, Domenicucci S. Epidemiology of atrial fibrillation: European perspective. Clin Epidemiol 2014;6:213–220
Maesen B, Nijs J, Maessen J, Allessie M, Schotten U. Post‐operative atrial fibrillation: a maze of mechanisms. Europace. 2012;14:159–174
Hansson GK. Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med 2005;352:1685- 95 4. Hilgendorf I, Swirski FK, Robbins CS. Monocyte fate in atherosclerosis. ArteriosclerThromb Vasc Biol 2015;35:272–9i 4. Ross R. Atheroslerosis-An inflammatory disease. N Engl J Med 1999;340:115–26
Nozawa N, Hibi K, Endo M, et al. Association between circulating monocytes and coronary plaque progression in patientswith acute myocardial infarction. Circ J 2010;74:1384–91
Ferro D, Parrotto S, Basili S, Alessandri C, Violi F. Simvastatin inhibits the monocyte expression of proinflammatory cytokines in patients with hypercholesterolemia.J Am Coll Cardiol 2000;36:427–431
W.H. Maisel, J.D. Rawn, W.G. Stevenson Atrial fibrillation after cardiac surgery Ann Intern Med, 135 (2001), pp. 1061-1073 8. Weymann A, Popov AF, Sabashnikov A, Ali-Hasan-Al-Saegh S, Ryazanov M, et al. Baseline and postoperative levels of Creactive protein and interleukins as inflammatory predictors of atrial fibrillation following cardiac surgery: a systematic review and meta-analysis. Kardiol Pol 2018;76:440–451 9. Zakkar M, Ascione R, James AF, et al. Inflammation, oxidative stress and postoperative atrial fibrillation in cardiac surgery. Pharmacol Ther 2015;154:13–20
Dreyer WJ, Phillips SC, Lindsey ML, et al. Interleukin 6 induction in the canine myocardium after cardiopulmonary bypass. J Thorac Cardiovasc Surg 2000;120:256–63
Hu YF, Chen YJ, Lin YJ, et al. Inflammation and the pathogenesis of atrial fibrillation. Nat Rev Cardiol 2015;12:230–43
Allessie M, Ausma J, Schotten U. Electrical, contractile and structural remodeling during atrial fibrillation. Cardiovasc Res 2002;54:230–46
Friedrichs K, Klinke A, Baldus S. Inflammatory pathways underlying atrial fibrillation. Trends Mol Med 2011;17:556–63
Suzuki A, Fukuzawa K, Yamashita T, Yoshida A, Sasaki N, Emoto T et al. Circulating intermediate CD14++ CD16 + monocytes are increased in patients with atrial fibrillation and reflect the functional remodelling of the left atrium. Europace 2016;19:40–7
Letsas KP, Weber R, Burkle G, Mihas CC, Minners J, Kalusche D et al. Pre-ablative predictors of atrial fibrillation re