SavedAdd your journal

Journals / Eurasian Journal of Medical Investigation / 2021 / Cilt: 5 - Sayı: 1

Mass Localization Relationship with Nodal Metastases in Right Lung Located Non-Small Cell Lung Cancer

Özgür Ömer YILDIZ
Eray ÇINAR
Anıl GÖKÇE
Pages
122–127
Publication Date
2022-10-12
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

But in complete mediastinal lymph node dissection,lobe-specific lymph nodes for metastasis should especially be considered.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objectives: Surgical treatment of non-small cell lung cancer (NSCLC) is the most effective treatment for operable cases.Correct staging is extremely important in both prognosis and treatment selection.
📊
Key Findings & Data:Lymph node invasion at the time ofdiagnosis is seen in 28-38% of NSCLC cases.
💡
Conclusion & Impact:But in complete mediastinal lymph node dissection,lobe-specific lymph nodes for metastasis should especially be considered.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: Surgical treatment of non-small cell lung cancer (NSCLC) is the most effective treatment for operable cases.Correct staging is extremely important in both prognosis and treatment selection. Lymph node invasion at the time ofdiagnosis is seen in 28-38% of NSCLC cases. The aim of our study is whether there is a relationship between the localization of the mass and the mediastinal lymph node region in the right lung non-small cell lung cancer.Methods: 235 patients with a mass in the right lung were included in the study. One patient who could not reach hisdata and 23 patients who had only mediastinoscopy were excluded from the study.Results: The location of the positive lymph node and the location of the mass were evaluated. Upper paratracheallymph node were observed in upper lobe tumors, subcarinal area metastases were observed in lower lobe and santaltumors. In the analysis, upper paratracheal (2N), lower paratracheal (4N) and interlobar (11N) lymph nodes for upperlobe tumors; subcarinal (7N) lymph node for lower lobe tumors; interlobar (11N) lymph node for central lesions werefound to be statistically significant in terms of lobe-specific metastatic lymph involvement.In the study, preoperativeevaluation of metastatic mediastinal lymph nodes with PET-CT was found to be statistically significant for mediastinallymph nodes except for station 8. High sensitivity (76.7%-96.6%) and low specificity values (18%-75%) were determined in the evaluation of metastatic lymph nodes.Conclusion: Because of PET-CT alone is not sufficient in medistinal staging, invasive evaluation is very important forcorrect staging. In the results of our study, upper paratracheal lymph node were observed in upper lobe tumors, subcarinal area metastases were observed in lower lobe and santal tumors. In the light of this information, lobe-specificlymph node dissection will not performed in right lung masses. But in complete mediastinal lymph node dissection,lobe-specific lymph nodes for metastasis should especially be considered.

🔖

Cite This Article

YILDIZ, Ö. Ö., ÇINAR, E., GÖKÇE, A. (2022). Mass Localization Relationship with Nodal Metastases in Right Lung Located Non-Small Cell Lung Cancer. Eurasian Journal of Medical Investigation, Cilt: 5 - Sayı: 1, 122–127. https://ajindex.com/articles/508588

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Jemal A, Thomas A, Murray T, Thun M. Cancer statistics, 2002. CA Cancer J Clin 2002;52:23–47
  2. Parkin DM, Bray F, Ferlay J, Pisani P. Global cancer statistics, 2002. CA Cancer J Clin 2005;55:74–108
  3. Ece T. Akciğer kanserine genel bakış. In: Aydıner A, Can G, editors. Akciğer kanserinde tedavi ve bakım. İstanbul: İpomet Matbaacılık; 2010. p. 1–6
  4. Akciğer ve Plevra Maligniteleri Çalışma Grubu. Akciğer kanseri tanı ve tedavi rehberi. Toraks Derg 2006;7:1–37
  5. Al-Sarraf N, Gately K, Lucey J, Wilson L, McGovern E, Young V. Lymph node staging by means of positron emission tomography is less accurate in non-small cell lung cancer patients with enlarged lymph nodes: Analysis of 1,145 lymph nodes. Lung Cancer 2008;60:62–8
  6. Semik M, Schmid C, Trösch F, Broermann P, Scheld HH. Lung cancer surgery--preoperative risk assessment and patient selection. Lung Cancer 2001;33 Suppl 1:S9–15
  7. Silvestri GA, Tanoue LT, Margolis ML, Barker J, Detterbeck F, American College of Chest Physicians. The noninvasive staging of non-small cell lung cancer: The guidelines. Chest 2003;123:147S–56
  8. Turkmen C, Sonmezoglu K, Toker A, Yilmazbayhan D, Dilege S, Halac M, et al. The additional value of FDG PET imaging for distinguishing N0 or N1 from N2 stage in preoperative staging of non-small cell lung cancer in region where the prevalence of inflammatory lung disease is high. Clin Nucl Med 2007;32:607–12
  9. Toloza EM, Harpole L, McCrory DC. Noninvasive staging of non-small cell lung cancer: A review of the current evidence. Chest 2003;123:137S–46
  10. Scott WJ, Dewan NA. Use of positron emission tomography to diagnose and stage iung cancer. Clin Pulm Med 1999;6:198– 204
  11. Global Burden of Disease Cancer Collaboration, Fitzmaurice C, Dicker D, Pain A, Hamavid H, Moradi-Lakeh M, et al. The global burden of cancer 2013. JAMA Oncol 2015;1:505–27
  12. Torre LA, Bray F, Siegel RL, Ferlay J, Lortet-Tieulent J, Jemal A. Global cancer statistics, 2012. CA Cancer J Clin 2015;65:87– 108
  13. Travis WD, Brambilla E, Noguchi M, Nicholson AG, Geisinger KR, Yatabe Y, et al. International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma. J Thorac Oncol 2011;6:244–85
  14. Lortet-Tieulent J, Soerjomataram I, Ferlay J, Rutherford M, Weiderpass E, Bray F. International trends in lung cancer incidence by histological subtype: Adenocarcinoma stabilizing in men but still incr