AI Summary & Key Takeaways
AI InsightConclusion: The current study demonstrated that SII, a novel marker based on blood peripheral cell counts, is a promis- ing prognostic factor for predicting CI-AK
📌 3 Key Takeaways
Abstract
Objectives: Systemic immune-inflammation index (SII) is a novel marker based on blood peripheral platelet, neutro- phil, and lymphocyte counts. We aimed to evaluate the worth of a SII in predicting contrast-induced nephropathy. Methods: A total number of 190 consecutive patients who underwent emergency percutaneous coronary interven- tion were included in the study. Patients were divided into two groups, according to contrast-induced acute kidney injury (CI-AKI) development. Patients with an increase in serum creatinine of ≥ 0.5 mg/dL or a 25% increase from base- line assessed 48-72 hours after angiography without an alternative explanation were considered CI-AKI. SII is calculated with a formula of total platelet count x total neutrophil count / total lymphocyte count. Results: Two groups were assigned according to CI-AKI development. CI-AKI (+) group included 33 patients, and CI- AKI (-) group included 157 patients. CI-AKI developed patients with higher serum creatinine levels, NLR (Neutrophil- Lymphocyte Ratio), and SII levels. Whereas, in the non-CI-AKI group, e-GFR, serum albumin levels, and ejection fraction were higher. Multivariable logistic regression analysis revealed that higher SII (p=0.001, [OR]=1.002[1001-1004]) were independent risk factors for CI-AKI. Conclusion: The current study demonstrated that SII, a novel marker based on blood peripheral cell counts, is a promis- ing prognostic factor for predicting CI-AK