Journals / Eurasian Journal of Medical Investigation / 2022 / Cilt: 6 - Sayı: 2

Evaluation of the Relationship between Blood Glucose Regulation and Hematological Indices in Patients with diabetes Mellitus

Pages
240–244
Publication Date
2022-10-12
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Our study established that high MPV and RDW levels are associated with high HbA1c levels.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: Diabetes mellitus is a subclinical and systemic inflammatory endothelial disease.
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Key Findings & Data:The aim of our study is to examine the relationship between HbA1c and complete blood count indices in patients with diabetic patients.
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Conclusion & Impact:Conclusion: Our study established that high MPV and RDW levels are associated with high HbA1c levels.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: Diabetes mellitus is a subclinical and systemic inflammatory endothelial disease. The relationship between erythrocyte and platelet indices and inflammation has been shown in many studies. With good glycemic control, mean platelet volume and red blood cell distribution width levels can be reduced, thus preventing or delaying vascular complications in patients. The aim of our study is to examine the relationship between HbA1c and complete blood count indices in patients with diabetic patients. Methods: This retrospective study included 8077 diabetic patients aged 18 and over followed in internal medicine outpatient clinics. Results: In our study, there was a difference between the groups in terms of RDW and MPV levels. The HbA1c levels showed a positive correlation with RDW and MPV levels. Conclusion: Our study established that high MPV and RDW levels are associated with high HbA1c levels.

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Cite This Article

FINDIKLI, H. A., SIRIKÇI, V., ERDOĞAN, M., KIRAÇ, C. O. (2022). Evaluation of the Relationship between Blood Glucose Regulation and Hematological Indices in Patients with diabetes Mellitus. Eurasian Journal of Medical Investigation, Cilt: 6 - Sayı: 2, 240–244. https://ajindex.com/articles/508520

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References (13)

  1. International Diabetes Federation. IDF DiabetesAtlas. 7th ed. (Last update December 13, 2017.) Available at: https://diabetesatlas. org/upload/resources/previous/files/7/IDF%20Diabetes% 20Atlas%207th.pdf. Accessed Mar 17, 2022
  2. Lontchi-Yimagou E, Sobngwi E, Matsha TE, Kengne AP. Diabetes mellitus and inflammation. Curr Diab Rep 2013;13:435–44
  3. May JE, Marques MB, Reddy VVB, Gangaraju R. Three neglected numbers in the CBC: The RDW, MPV, and NRBC count. Cleve Clin J Med 2019;86:167–72
  4. Aktas G, Alcelik A, Tekce BK, Tekelioglu V, Sit M, Savli H. Red cell distribution width and mean platelet volume in patients with irritable bowel syndrome. Prz Gastroenterol 2014;9:160–3
  5. Mantzoros CS, Li T, Manson JE, Meigs JB, Hu FB. Circulating adiponectin levels are associated with better glycemic control, more favorable lipid profile, and reduced inflammation in women with type 2 diabetes. J Clin Endocrinol Metab 2005;90:4542–8
  6. Tonelli M, Sacks F, Arnold M, Moye L, Davis B, Pfeffer M; for the Cholesterol and Recurrent Events (CARE) Trial Investigators. Relation between red blood cell distribution width and cardiovascular event rate in people with coronary disease. Circulation 2008;117:163–8
  7. Pickup JC, Crook MA. Is type II diabetes mellitus a disease of the innate immune system? Diabetologia 1998;41:1241–8
  8. Pickup JC, Mattock MB, Chusney GD, Burt D. NIDDM as a disease of the innate immune system: association of acutephase reactants and interleukin-6 with metabolic syndrome X. Diabetologia 1997;40:1286–92
  9. Rizzo MR, Barbieri M, Marfella R, Paolisso G. Reduction of oxidative stress and inflammation by blunting daily acute glucose fluctuations in patients with type 2 diabetes: role of dipeptidyl peptidase-IV inhibition. Diabetes Care 2012;35:2076–82
  10. Ani C, Ovbiagele B. Elevated red blood cell distribution width predicts mortality in persons with known stroke. J Neurol Sci 2009;277:103–8
  11. Sharpe PC, Trinick T. Mean platelet volume in diabetes mellitus. Q J Med 1993;86:739–42
  12. Oh HJ, Park JT, Kim JK, Yoo DE, Kim SJ, Han SH, et al. Red blood cell distribution width is an independent predictor of mortality in acute kidney injury patients treated with continuous renal replacement therapy. Nephrol Dial Transplant 2012;27:589–94
  13. Murat SN, Duran M, Kalay N, Gunebakmaz O, Akpek M, Doger C, et al. Relation between mean platelet volume and severity of atherosclerosis in patients with acute coronary syndromes. Angiology 2013;64:131–6