Association of Neopterin and Wound Healing Process

Objective & Hypothesis:DOI: 10.26650/experimed.2019.19014Human monocytes/macrophages produce neopterin when stimulated by the cytokine interferon-γ.

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Key Findings & Data:The concentration of neopterin in body fluids such as serum, cerebrospinal fluid and urine can be measured and increased concentrations of neopterin provides information about infections states.

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Conclusion & Impact:Experimed 2019; 9(2): 65-8.

🔬Design:Research Article

📍Scope:2019 Verileri

⚙️Variables:Neopterin · yara iyileşmesi · antioksidan

Abstract

DOI: 10.26650/experimed.2019.19014Human monocytes/macrophages produce neopterin when stimulated by the cytokine interferon-γ. The concentration of neopterin in body fluids such as serum, cerebrospinal fluid and urine can be measured and increased concentrations of neopterin provides information about infections states. Nowadays, neopterin is as a marker in neurological and cardiovascular diseases during cellular immune activation.Cite this article as: Hepokur C, Mısır S, Hepokur Aİ, Yaylım İ. Association of Neopterin and Wound Healing Process. Experimed 2019; 9(2): 65-8.

Özet

DOI: 10.26650/experimed.2019.19014İnsan monositleri/makrofajları, sitokin interferon-γ tarafından uyarıldığında neopterin üretir. Serum, beyin omurilik sıvısı ve idrar gibi vücut sıvılarında neopterinin konsantrasyonu ölçülebilir ve artan neopterin konsantrasyonları enfeksiyon durumları hakkında bilgi sağlar. Günümüzde neopterin, hücresel immün aktivasyonu sırasındaki nörolojik ve kardiyovasküler hastalıklarda bir belirteç olarak kullanılır.Cite this article as: Hepokur C, Mısır S, Hepokur Aİ, Yaylım İ. Association of Neopterin and Wound Healing Process. Experimed 2019; 9(2): 65-8.

Keywords

Neopterin yara iyileşmesi antioksidan immun sistem aktivasyonu Antioxidant immune system activation neopterin wound healing

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Cite This Article

HEPOKUR, C., MISIR, S., HEPOKUR, A. İ., YAYLIM, İ. (2019). Association of Neopterin and Wound Healing Process. Experimed, Cilt: 9 - Sayı: 2, 65–68. https://ajindex.com/articles/50843

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References (1)

1. Mahmoud RA, El-Gendi HI, Ahmed HH. Serum neopterin, tumor necrosis factor-α and soluble tumor necrosis factor receptor II (p75) levels and disease activity in Egyptian female patients with systemic lupus erythematosus. Clin Biochem 2005; 38: 134-41. [CrossRef] 2. Shady MMA, Fathy HA, Ali A, Youness ER, Fathy GA. Association of neopterin as a marker of immune system activation and juvenile rheumatoid arthritis activity. J Pediatr 2015; 91: 352-7. [CrossRef] 3. Krcmova L, Solichova D, Melichar B, Kasparova M, Plisek J, Sobotka L, et al. Determination of neopterin, kynurenine, trypophan and creatinine in human serum by high throuput HPLC. Talanta 2011; 85: 1466-71. [CrossRef] 4. Zhao Ars H, Yin S, Fan J. High plasma neopterin levels in Chinese children with autism spectrum disorders. Int J Devl Neuroscience 2015; 41: 92-7. [CrossRef] 5. Garcia-Gonzalez MJ, Dominguez-Rodriguez A, Abreu-Gonzalez P. Light -Dark variations in neopterin serum levels in patients with st-segment elevation acute coronary syndrome undergoing primary angioplasty. Rev Esp Cardiol 2008; 61: 1280-6. [CrossRef] 6. Ursavaş A, Karadağ M, Oral AY, Demirdogen E, Oral HB, Ege E. Association between serum neopterin, obesity and daytime sleepiness in patients with obstructive sleep apnea. Respir Med 2008; 102: 1193-7. [CrossRef] 7. Arshadi D, Nikbin B, Shakiba Y, Kiani A, Jamshidi AR, Boroushaki MT. Plasma level of neopterin as a marker of disease activity in treated rheumatoid arthritis patients: Association with gender, disease activity and anti-CCP antibody. Int Immunopharmacol 2013; 17: 763-7. [CrossRef] 8. Ercan N, Tuzcu N, Başbuğ O, Gök K, Işıdan H, Oğrak YZ. Evaluation of important biomarkers in healthy cattle. Kafkas Univ Vet Fak Dergisi 2014; 20: 749-55. [CrossRef] 9. Schroecksnadel K, Frick B, Winkler C, Fuith Lothar C, Fuchs D. Relationship between homocysteine and neopterin concentrationsin patients with gynecological cancer. Cancer Lett 2006; 240: 198-202. [CrossRef] 10. Sipahi H, Becker K, Gostner JM, Charehsaz M, Kırmızıbekmez H, Schennach H, et al. Effects of globularifolin on cell survival, nuclear factor-κB activity, neopterin production, tryptophan breakdown and free radicals in vitro. Fitoterapia 2014; 92: 85-92. [CrossRef] 11. Kaski JC, Consuegra-Sanchez L, Fernandez-Berges DJ, Cruz-Fernandez JM, Garcia-Moll X, Marrugat J, et al. Elevated serum neopterin levels and adverse cardiac events at 6 months follow-up in mediterranean patients with non-ST- segment elevation acute c