Thirty-Day Mortality in Septic Shock Patients is Directly Associated with High Disease Severity Score but not with the Length of Stay in the Emergency Department
Patients with anAPACHE-II score ≥20 or a SOFA score ≥8 had longer MV duration and ICU and hospital stay, greater RRT and MV need and higher mortality ratethan the patients with lower value (p
📌 3 Key Takeaways
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Objective & Hypothesis:Aim: To determine the factors associated with mortality in septic shock patients who are transferred from the emergency department (ED)to the intensive care unit (ICU).Materials and Methods: We used the data of 206 patients who were admitted to the ED with infection and were diagnosed with septic shockbetween December 2016 and January 2020.Results: The 206 patients had a mean Glasgow Coma score of 11.42 (range: 3-15), mean Acute Physiology and Chronic Health Evaluation(APACHE-II) score of 21.66 (range: 8-49) and mean Sequential Organ Failure Assessment Score (SOFA) of 10.24 (range: 2-22).
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Key Findings & Data:There were nodifferences in 30-day mortality and in need for renal replacement therapy (RRT) or mechanical ventilation (MV) between patients transferredto the ICU within 1 hour of ED admission and those transferred to the ICU more than 6 hours after ED admission (p>0.05).
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Conclusion & Impact:Patients with anAPACHE-II score ≥20 or a SOFA score ≥8 had longer MV duration and ICU and hospital stay, greater RRT and MV need and higher mortality ratethan the patients with lower value (p
🔬Design:Research Article
📍Scope:2016 Verileri
⚙️Variables:Domain Parameters
Abstract
Aim: To determine the factors associated with mortality in septic shock patients who are transferred from the emergency department (ED)to the intensive care unit (ICU).Materials and Methods: We used the data of 206 patients who were admitted to the ED with infection and were diagnosed with septic shockbetween December 2016 and January 2020.Results: The 206 patients had a mean Glasgow Coma score of 11.42 (range: 3-15), mean Acute Physiology and Chronic Health Evaluation(APACHE-II) score of 21.66 (range: 8-49) and mean Sequential Organ Failure Assessment Score (SOFA) of 10.24 (range: 2-22). There were nodifferences in 30-day mortality and in need for renal replacement therapy (RRT) or mechanical ventilation (MV) between patients transferredto the ICU within 1 hour of ED admission and those transferred to the ICU more than 6 hours after ED admission (p>0.05). Patients with anAPACHE-II score ≥20 or a SOFA score ≥8 had longer MV duration and ICU and hospital stay, greater RRT and MV need and higher mortality ratethan the patients with lower value (p
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Cite This Article
ELAY, G., AL, B. (2022). Thirty-Day Mortality in Septic Shock Patients is Directly Associated with High Disease Severity Score but not with the Length of Stay in the Emergency Department. Eurasian Journal of Emergency Medicine, Cilt: 19 - Sayı: 3, 172–177. https://ajindex.com/articles/507979
Singer M, Deutschman CS, Seymour C, Shankar-Hari M, Annane D, Bauer M, et al. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) JAMA - J Am Med Assoc. 2016;315:801-10
Reinhart K, Daniels R, Kissoon N, Machado FR, Schachter RD, Finfer S. Recognizing sepsis as a global health priority — A WHO Resolution. N Engl J Med. 2017;377:414-7
Tupchong K, Koyfman A, Foran M. Sepsis, severe sepsis, and septic shock: A review of the literature. African J Emerg Med. 2015;2:127-35
Rhodes A, Evans LE, Alhazzani W, Levy MM, Antonelli M, Ferrer R, et al. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016. Crit Care Med. 2017;45:486-552
Angus DC, van der Poll T. Severe sepsis and septic shock. N Engl J Med. 2013;369:840-51
Baykara N, Akalin H, Arslantaş MK, Hanci V, Çağlayan Ç, Kahveci F, et al. Epidemiology of sepsis in intensive care units in Turkey: a multicenter, pointprevalence study. Crit Care. 2018;22:93
Labelle A, Juang P, Reichley R, Micek S, Hoffmann J, Hoban A, et al. The determinants of hospital mortality among patients with septic shock receiving appropriate initial antibiotic treatment. Crit Care Med. 2012;40:2016-21
Groenland CNL, Termorshuizen F, Rietdijk WJR, van den Brule J, Dongelmans DA, de Jonge E, et al. Emergency Department to ICU Time Is Associated with Hospital Mortality: A Registry Analysis of 14,788 Patients From Six University Hospitals in The Netherlands. Crit Care Med. 2019;47:1564-71
Carter AW, Pilcher D, Bailey M, Cameron P, Duke GJ, Cooper J. Is ED length of stay before ICU admission related to patient mortality? Emerg Med Australas. 2010;22:145-50
Thijssen WAMH, Kraaijvanger N, Barten DG, Boerma MLM, Giesen P, Wensing M. Impact of a well-developed primary care system on the length of stay in emergency departments in the Netherlands: a multicenter study. BMC Health Serv Res. 2016;16:149
Mahsanlar Y, Parlak I, Yolcu S, Akay S, Demirtas Y, Eryigit V. Factors Affecting the Length of Stay of Patients in Emergency Department Observation Units at Teaching and Research Hospitals in Turkey. Turk J Emerg Med. 2016;14:3-8
Erkuran MK, Duran A, Ocak T, Citisli V, Kaya H. The impact of the duration of admission to the emergency room on the mortality of intensive care patients. Niger J Clin Pract. 2014;17:320-3. 14.