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Journals / Erciyes Üniversitesi Veteriner Fakültesi Dergisi / 2004 / Cilt: 1 - Sayı: 1

Development, functions and histochemical properties of T lymphocytes

T lenfositler gelişimi, fonksiyonları ve histokimyasal özellikleri

Feyzullah BEYAZ
Pages
61–66
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review, some information was given about development, functions and histochemical properties of T lymphocytes.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:T lymphocytes (T cells) are differentiated from embrional pluripotent stem cells in bone marrow in that they migrate to the thymic cortex where they become immunocompetent similar to TCR and CD in expressing their specific cell membranes.
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Key Findings & Data:These molecules permit them to perform their immunological functions.
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Conclusion & Impact:In this review, some information was given about development, functions and histochemical properties of T lymphocytes.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

T lymphocytes (T cells) are differentiated from embrional pluripotent stem cells in bone marrow in that they migrate to the thymic cortex where they become immunocompetent similar to TCR and CD in expressing their specific cell membranes. These molecules permit them to perform their immunological functions. Immunocompetent T lymphocytes that have been activated by interaction with an antigen also transform into lymphoblasts that proliferative and differantiate into cytotoxic, helper, suppressor and memory which is subsets of T lymphocytes. In this review, some information was given about development, functions and histochemical properties of T lymphocytes.

Özet

Kemik iliğinde embriyonal pluripotent köken hücrelerden (hemasitoblast) farklılaşan pre-T lenfositler (pre-T hücreleri) umusun korteksine göçerler. Timik kortekste, hücre membranlarında TCR (T hücre antijen reseptörü) ve CD (Yüzey farklılaşma antijenleri) gibi spesifik yüzey moleküllerinin kazanılması ile birlikte immünolojik fonksiyonları yerine getirebilen immun yetenekli T lenfositler oluşur. İmmun yetenekli T lenfositler, antijenlerle etkileşimleri sonucunda aktive olarak len-foblastlara dönüşürler. Lenfoblastların prolifere ve diferensiye olması ile sitotoksik, yardımcı, baskılayıcı ve bellek T lenfosit alt grupları meydana gelir. Bu derlemede, T lenfositlerin gelişimi, fonksiyonları ve histokimyasal özelliklerine yönelik bilgiler verildi.

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Cite This Article

BEYAZ, F. (2022). Development, functions and histochemical properties of T lymphocytes. Erciyes Üniversitesi Veteriner Fakültesi Dergisi, Cilt: 1 - Sayı: 1, 61–66. https://ajindex.com/articles/504132

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References (1)

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