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Journals / Ankara Üniversitesi Veteriner Fakültesi Dergisi / 2018 / Volume: 65 Issue: 4

The immunohistochemical localization of the fibronectin receptor (Integrin β1) and laminin in the bitch uterus during the estrous cycle

Güner Küçük Bayram
Narin Liman
Feyzullah Beyaz
Emel Alan
Pages
—
Publication Date
2018-11-09
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Laminin and the fibronectin receptor (Integrin β 1 ) were found to be present at high intensity in the endometrium of the bitch uterus at the luteal stage.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:In mammals, the purpose of the estrous cycle is the successful progression of implantation and pregnancy.
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Key Findings & Data:In this study, we investigated the localization of the fibronectin receptor (Integrin β 1 ), a member of the integrin family, and laminin, an extracellular matrix protein, in the bitch uterus throughout the estrous cycle.
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Conclusion & Impact:Laminin and the fibronectin receptor (Integrin β 1 ) were found to be present at high intensity in the endometrium of the bitch uterus at the luteal stage.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Bitch · estrous cycle · fibronectin

Abstract

In mammals, the purpose of the estrous cycle is the successful progression of implantation and pregnancy. The endometrium undergoes several changes during the estrous cycle. The extracellular matrix proteins have a likely role in the maintenance of a healthy endometrium. In this study, we investigated the localization of the fibronectin receptor (Integrin β 1 ), a member of the integrin family, and laminin, an extracellular matrix protein, in the bitch uterus throughout the estrous cycle. In the bitch uterus, immunoreactions of similar intensity were observed for the fibronectin receptor (Integrin β 1 ) in the myometrium, perimetrium, peritoneal mesothelial cells and uterine vasculature, and for laminin in the peritoneal mesothelial cells, throughout the estrous cycle. Laminin and the fibronectin receptor (Integrin β 1 ) were found to be present at high intensity in the endometrium of the bitch uterus at the luteal stage.

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Cite This Article

Bayram, G. K., Liman, N., Beyaz, F., Alan, E. (2018). The immunohistochemical localization of the fibronectin receptor (Integrin β1) and laminin in the bitch uterus during the estrous cycle. Ankara Üniversitesi Veteriner Fakültesi Dergisi, Volume: 65 Issue: 4. https://doi.org/10.1501/Vetfak_0000002868

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