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Journals / Erciyes Tıp Dergisi / 2006 / Cilt: 28 - Sayı: 2

İnsan derisi: bir ekstra pulmoner sürfaktan salınım bölgesi

Human skin is as an extra-pulmonary site of secretion of surfactant proteins

Orhan KANKAVİ
Pages
82–91
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This editorial describes the surfactant proteins and their possible function within the skin

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Surfactant is a surface active material composed of both lipids and proteins which is produced by alveolar type II pneumocytes in the lung.
📊
Key Findings & Data:Review data demonstrates that human skin expresses surfactant proteins constitutively in skin tissue.
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Conclusion & Impact:This editorial describes the surfactant proteins and their possible function within the skin
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Surfactant is a surface active material composed of both lipids and proteins which is produced by alveolar type II pneumocytes in the lung. Surfactant enhances pathogen clearence and regulates adaptive and innate immune-cell functions. Recently, the presence of surfactant proteins in human skin, being found in variable amounts in epidermis, dermis, hair follicles, sweat and sebum was reported. These surfactant proteins show characteristics that may be critical to local barrier and defence functions of the skin. Review data demonstrates that human skin expresses surfactant proteins constitutively in skin tissue. This editorial describes the surfactant proteins and their possible function within the skin

Özet

Surfaktant yüzey aktif materyal olup lipit ve proteinlerden oluşur ve akciğerlerde alveolar tip II pnömositler tarafından üretilir. Surfaktant, patojenlerin arındırılması ile adaptif ve immün hücre fonksiyonlarının düzenlenmesini artırır. Surfaktant proteinlerinin, insan deri dokusunda ve farklı oranlarda, epidermis, dermis, kıl folikülleri, ter ve sebumda bulunduğu yakın zamanda gösterilmiştir. Derinin bölgesel bariyer ve savunma mekanizmasında surfaktant proteinlerinin kritik moleküller olduğu gösterilmiştir. Derlemede sunulan veriler insan deri dokusunun surfaktant proteinlerinin, derinin bir bileşeni olarak salgılandığını göstermektedir. Bu derleme, surfaktant proteinlerinin derideki olası fonksiyonlarını tanımlamaktadır

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Cite This Article

KANKAVİ, O. (2022). İnsan derisi: bir ekstra pulmoner sürfaktan salınım bölgesi. Erciyes Tıp Dergisi, Cilt: 28 - Sayı: 2, 82–91. https://ajindex.com/articles/502769

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