Journals / Erciyes Tıp Dergisi / 2008 / Cilt: 30 - Sayı: 4

Photodynamic therapy of subfoveal choroidal neovascularization in pathologic myopia

Patolojik miyopiye bağlı subfoveal koroidal neovaskülarizasyon gelişen olgularda fotodinamik tedavi

Pages
238–241
Publication Date
2022-10-17
DOI
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Mean initial LogMAR BCVA was 0.52, which improved to a value of 0.38 following treatment.Conclusion: Photodynamic therapy (PDT) with verteporfin is an effective and safe treatment option in patients with subfoveal CNV secondary to pathologic myopia to stabilize and improve the visual acuity.

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: To evaluate the outcomes of photodynamic therapy (PDT) with verteporfin in patients with subfoveal choroidal neovascularisation (CNV) caused by pathologic myopia.
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Key Findings & Data:Materials and Methods: Eight eyes of 8 patients with subfoveal choroidal neovascular membran (CNV) due to pathologic myopia were included in the study.
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Conclusion & Impact:Mean initial LogMAR BCVA was 0.52, which improved to a value of 0.38 following treatment.Conclusion: Photodynamic therapy (PDT) with verteporfin is an effective and safe treatment option in patients with subfoveal CNV secondary to pathologic myopia to stabilize and improve the visual acuity.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: To evaluate the outcomes of photodynamic therapy (PDT) with verteporfin in patients with subfoveal choroidal neovascularisation (CNV) caused by pathologic myopia. Materials and Methods: Eight eyes of 8 patients with subfoveal choroidal neovascular membran (CNV) due to pathologic myopia were included in the study. All patients had a > -6.00 spheric equivalent diopters, and pathologic myopia fundus findings. Best-corrected visual acuity (BCVA), fundus fluorescein angiography findings and complications were recorded before and after PDT treatment.Results: The study group included 5 females and 3 males with a mean age of 47.8 years. In 6 eyes (75%), visual acuity improved or remained stable after a mean follow up period of 10.6 months. The mean PDT treatment value was 2.0±0.75. Mean initial LogMAR BCVA was 0.52, which improved to a value of 0.38 following treatment.Conclusion: Photodynamic therapy (PDT) with verteporfin is an effective and safe treatment option in patients with subfoveal CNV secondary to pathologic myopia to stabilize and improve the visual acuity.

Özet

Amaç: Sunulan çalışmada patolojik myopiye bağlı subfoveal koroidal neovaskülarizasyon (KNV) gelişen olgularda verteporfin ile fotodinamik tedavi (PDT) sonuçlarının değerlendirilmesi amaçlandı. Gereç ve Yöntemler: Yüksek myopiye bağlı subfoveal koroidal neovaskülarizasyon (KNV) gelişen 8 hastanın 8 gözü çalışma kapsamına alındı. Olguların tümünde sferik ekivalan değeri - 6 dioptrinin üzerinde idi ve patolojik myopi bulguları mevcut idi. PDT öncesi ve sonrası en iyi düzeltilmiş görme keskinliği (DGK), floresein anjiografi bulguları ve komplikasyonlar kaydedildi.Bulgular: Olguların 5'i kadın, 3'ü erkek olup ortalama yaş 47,8 yıl idi. Ortalama 10,6 aylık takip sonunda 6 gözde (%75) görme keskinliğinde artış veya stabilizasyon sağlandı. Ortalama fotodinamik tedavi seansı 2,0±0,75 idi. Başlangıç LogMAR DGK değeri 0,52 iken tedavi sonrası son takipte 0,38 idi.Sonuç: Vertoporfinle yapılan fotodinamik tedavi patolojik miyopiye bağlı subfoveal KNV'de olan olgularda görmenin stabilize edilmesinde ve iyileştirilmesinde etkili ve güvenli bir yöntemdir.

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Cite This Article

ERKILIÇ, K., YARBAĞ, A., TUZCU, E. A., ÖNER, A., ÖZKIRIŞ, A., İLHAN, Ö., PANGAL, E. (2022). Photodynamic therapy of subfoveal choroidal neovascularization in pathologic myopia. Erciyes Tıp Dergisi, Cilt: 30 - Sayı: 4, 238–241. https://ajindex.com/articles/502659

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References (16)

  1. Karacorlu SA, Ozdemir H, Senturk F, Karacorlu M. Optical coherence tomography after photodynamic therapy for patients with pathologic myopia. Retina 2006;26:752- 756
  2. Grossniklaus HE, Green WR. Pathologic findings in pathologic myopia. Retina 1992;12:127-133
  3. Curtin BJ. Physiologic vs pathologic myopia: genetics vs environment. Ophthalmology 1979; 86:681-691
  4. Sperduto RD, Seigel D, Roberts J, Rowland M. Prevalence of myopia in the United States. Arch Ophthalmol 1983; 101:405-407
  5. Hotchkiss ML, Fine SL. Pathologic myopia and choroidal neovascularization. Am J Ophthalmol 1981; 91:177-183
  6. Jalkh AE, Weiter JJ, Trempe CL, Pruett RC, Schepens CL. Choroidal neovascularization in degenerative myopia: role of laser photocoagulation. Ophthalmic Surg 1987; 18:721-725 7) Ruiz-Moreno JM, de La Vega C. Surgical removal of subfoveal choroidal neovascularisation in highly myopic patients. Br J Ophthalmol 2001; 85:1041-1043
  7. Verteporfin in Photodynamic Therapy Study Group. Photodynamic therapy of subfoveal choroidal neovascularization in pathologic myopia with verteporfin. 1-year results of a randomized clinical trial—VIP report no
  8. Ophthalmology 2001; 108:841-852
  9. Yoshida T, Ohno-Matsui K, Ohtake Y, et al. Long-term visual prognosis of choroidal neovascularization in high myopia: a comparison between age groups. Ophthalmology 2002;109:712-719
  10. Tabandeh H, Flynn HW Jr, Scott IU, et al. Visual acuity outcomes of patients 50 years of age and older with high myopia and untreated choroidal neovascularization Ophthalmology 1999; 106:2063-2067
  11. Avila MP, Weiter JJ, Jalkh AE, Trempe CL, Pruett RC, Schepens CL. Natural history of choroidal neovascularization in degenerative myopia. Ophthalmology 1984;91:1573-1581
  12. Adelberg DA, Del Priore LV, Kaplan HJ. Surgery for subfoveal membranes in myopia, angioid streaks, and other disorders. Retina 1995; 15:198-205
  13. Ruiz-Moreno JM, de La Vega C. Surgical removal of subfoveal choroidal neovascularisation in highly myopic patients. Br J Ophthalmol 2001;85:1041-1043
  14. Fujikado T, Ohji M, Saito Y, Hayashi A, Tano Y. Visual function after foveal translocation with scleral shortening in patients with myopic neovascular maculopathy. Am J Ophthalmol 1998;125:647-656
  15. Pece A, Isola V, Vadala M, Matranga D. Photodynamic therapy wıth verteporfın for subfoveal choroıdal neovascularızatıon secondary to pathologıc myopıa: long-term study. Retina 2006;26:746-751
  16. Krebs I, Binder S, Stolba U, Glittenbe