SavedAdd your journal

Journals / Erciyes Tıp Dergisi / 2013 / Cilt: 35 - Sayı: 3

Yenidoğanlarda beyin yüzey alanının stereolojik olarak hesaplanması

Estimation of cerebral surface area of the newborn brain using stereological methods

Niyazi ACER
Tolga ERTEKİN
Özlem ÖZÇELİK
Şerife ÇINAR
Selim DOĞANAY
Pages
136–141
Publication Date
2022-10-17
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We estimated cerebral surface area using the vertical section method in 4 orientations, the results were 210±41, 202±36.4 cm2, 267±41 cm2 and 293±52.6 cm2 two post processing, coronal and sagittal planes, respectively.Conclusion: We consider that our study will be a good source for similar studies performed in future.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: In this study, normal values of the newborn brain’s Materials and Methods: In this study we investigated MRI im- volume and surface area were calculated for the early diagno- ages of 5 newborn cadavers.
📊
Key Findings & Data:Cycloid probe was superimposed on images,which were obtained by using the vertical section method, for suface area estimation of the brain and then results were obtained.Results: We estimated the mean cerebral volume as 246±79.4cm3 and 256±71.1cm3, by the point counting technique and gold standard, respectively.
💡
Conclusion & Impact:We estimated cerebral surface area using the vertical section method in 4 orientations, the results were 210±41, 202±36.4 cm2, 267±41 cm2 and 293±52.6 cm2 two post processing, coronal and sagittal planes, respectively.Conclusion: We consider that our study will be a good source for similar studies performed in future.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: In this study, normal values of the newborn brain’s Materials and Methods: In this study we investigated MRI im- volume and surface area were calculated for the early diagno- ages of 5 newborn cadavers. Stereologic measurements were sis of disease related to the central nervous system which may performed to calculate the volume and surface area of the develop in newborns. brain. We used Archimedes principle as a gold standard and the point counting method as a stereologic method for volume estimation of the newborn brains. Cycloid probe was superimposed on images,which were obtained by using the vertical section method, for suface area estimation of the brain and then results were obtained.Results: We estimated the mean cerebral volume as 246±79.4cm3 and 256±71.1cm3, by the point counting technique and gold standard, respectively. We estimated cerebral surface area using the vertical section method in 4 orientations, the results were 210±41, 202±36.4 cm2, 267±41 cm2 and 293±52.6 cm2 two post processing, coronal and sagittal planes, respectively.Conclusion: We consider that our study will be a good source for similar studies performed in future.

Özet

Amaç: Bu çalışmada, yenidoğanlarda beyin hacmini ve yüzey alanını hesaplayarak, oluşabilmesi muhtemel santral sinir sistemi hastalıklarının erken dönemde teşhis edilebilmesi için normal değerlerin elde edilmesi amaçlandı. Gereç ve Yöntemler: Bu çalışmada 5 adet yenidoğan kadavrasına ait MRI görüntüleri incelendi. Görüntüler üzerinden beyin hacmini ve yüzey alanını hesaplayabilmek için stereolojik ölçümler yapıldı. Beyin hacmini hesaplayabilmek için stereolojik bir yöntem olan nokta sayım yöntemi ve altın standart olarak kabul edilen Arşimet Prensibi kullanıldı. Beyin yüzeyalanını hesaplayabilmek için ise vertical section tekniği ile alınan görüntüler üzerine sikloid sonda atıldı ve sonuçlar elde edildi. Bulgular: Çalışmamızda, MRI görüntülerinden Cavalieri yöntemiyle elde edilen hacim değeri ve altın standart olarak bilinen Arşimet prensibiyle elde edilen hacim değeri sırasıyla 246±79,4 cm3 ve 256±71,1 cm3 olarak hesaplandı. Dikey kesitmetodu kullanılarak beyin yüzey alanı 4 oryantasyonda hesaplandı; sonuçta iki post processing, koronal ve sagittal planda sırasıyla 202±36,4 cm2, 210±41 cm2, 267±41 cm2 ve 293±52,6cm2 olarak tespit edildi. Sonuç: Çalışmamızın benzer konularda yapılacak olan çalışmalara kaynak olacağı kanaatindeyiz.

🔖

Cite This Article

ACER, N., ERTEKİN, T., ÖZÇELİK, Ö., ÇINAR, Ş., DOĞANAY, S. (2022). Yenidoğanlarda beyin yüzey alanının stereolojik olarak hesaplanması. Erciyes Tıp Dergisi, Cilt: 35 - Sayı: 3, 136–141. https://ajindex.com/articles/502421

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (15)

  1. Odar İV. Anatomi Ders Kitabı (1. Baskı), Sistem Ofset, Ankara 1986.s.239
  2. Arıncı K, Elhan A. Anatomi (4. Baskı), Güneş Kitabevi, Ankara 2006 (2).s.299-313
  3. Benes FM, Turtle M, Khan Y, Farol P Myelination of a key relay zone in the hippocampal formation occurs in the human brain during childhood, adolescence, and adulthood. Arch Gen Psychiatry 1994; 51(6): 477-84
  4. Caviness VS Jr, Kennedy DN, Richelme C, Rademacher J, Filipek PA. The human brain age 7-11 years: a volumetric analysis based on magnetic resonance images. Cereb Cortex 1996; 6(5): 726-36
  5. Giedd JN, Snell JW, Lange N, Rajapakse JC, Casey BJ, Kozuch PL, et al. Quantitative magnetic resonance imaging of human brain development: ages 4-18. Cereb Cortex 1996; 6(4): 551-60
  6. Creasey H, Rumsey JM, Schwartz M, Duara R, Rapoport JL, Rapoport SI. Brain morphometry in autistic men as measured by volumetric computed tomography. Arch Neurol 1986; 43(7): 669-72
  7. Wang D, Chalk JB, Rose SE, de Zubicaray G, Cowin G, Galloway GJ, et al. MR image-based measurement of rates of change in volumes of brain structures. Part II: application to a study of Alzheimer’s disease and normal aging. Magn Reson Imaging 2002; 20(1): 41-8
  8. Armstrong E, Schleicher A, Omran H, Curtis M, Zilles K. The ontogeny of human gyrification. Cereb Cortex 1995; 5(1): 56-63
  9. Kulynych JJ, Luevano LF Jones DW, Weinberger DR. Cortical abnormality in schizophrenia: an in vivo application of the gyrification index. Biol Psychiatry 1997; 41(10): 995-9
  10. Schmitt JE, Watts K, Eliez S, Bellugi U, Galaburda AM, Reiss AL. Increasedgyrification in Williams syndrome: evidence using 3D MRI methods. Dev Med Child Neurol 2002; 44(5): 292-5
  11. Ronan L, Doherty CP Delanty N, Thornton J, Fitzsimons M. Quantitative MRI: a reliable protocol for measurement of cerebral gyrification using stereology. Magn Reson Imaging 2006; 24(3): 265-72
  12. Baddeley AJ, Gundersen HJ, Cruz-Orive LM. Estimation of surface area from vertical sections. J Microsc 1986; 142(3): 259-76
  13. Acer N, Sahin B, Ekinci N, Ergür H, Basaloglu H. Relation between intracranial volume and the surface area of the foramen magnum. J Craniofac Surg 2006; 17(2): 326-30
  14. Mayhew TM, Mwamengele GL, Dantzer V Comparative morphometry of the mammalian brain: estimates of cerebral volumes and cortical surface areas obtained from macroscopic slices. J Anat 1990; 172: 191-200
  15. Cruz-Orive LM. A general variance predictor for Cavalieri slices. J Microsc 2006; 222(3): 158-65.