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Journals / European Journal of Therapeutics / 2020 / Cilt: 26 - Sayı: 2

HLA-G with Benefits and Damages: A Review

İbrahim PİRİM
Burcu CERCİ GÜRBÜZ
Mustafa SOYOZ
Tülay KILIÇARSLAN AYNA
Pages
138–142
Publication Date
2022-10-12
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review it was aimed to evaluate the benefits and damages of the HLA-G by considering both the expression levels and polymorphisms.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Human leucocyte antigen-G (HLA-G) is a non-classical HLA that researchers primarily focused on association with the complications of pregnancy.
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Key Findings & Data:Recent studies about the immunomodulatory characteristics of HLA-G showed that this molecule is not only important in pregnancy but also have effects on transplantation, autoimmune diseases, cancer and infectious diseases.
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Conclusion & Impact:In this review it was aimed to evaluate the benefits and damages of the HLA-G by considering both the expression levels and polymorphisms.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Human leucocyte antigen-G (HLA-G) is a non-classical HLA that researchers primarily focused on association with the complications of pregnancy. Recent studies about the immunomodulatory characteristics of HLA-G showed that this molecule is not only important in pregnancy but also have effects on transplantation, autoimmune diseases, cancer and infectious diseases. The restricted polymorphic nature and the disease association has also showed in various studies. In this review it was aimed to evaluate the benefits and damages of the HLA-G by considering both the expression levels and polymorphisms.

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Cite This Article

PİRİM, İ., GÜRBÜZ, B. C., SOYOZ, M., AYNA, T. K. (2022). HLA-G with Benefits and Damages: A Review. European Journal of Therapeutics, Cilt: 26 - Sayı: 2, 138–142. https://ajindex.com/articles/501876

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