Journals / Endoskopi / 2018 / Cilt: 26 - Sayı: 3

Prevalence and histopathological characteristics of colorectal neoplastic and nonneoplastic diseases in Azerbaijan

Azerbaycan’da kolorektal neoplastik ve nonneoplastik hastalıkların oranı ve histopatolojik özellikleri

Journal
Endoskopi
Pages
78–83
Publication Date
2022-10-11
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It has been found that there is a very significant reciprocal relationship between complaints and the rate of inflammatory diseases of the colon (odds ratio=10.59).

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Background and Aims: It is known that many of the colorectal diseases are related to age, gender, race, ethnicity and geographical position of peo-ple.
📊
Key Findings & Data:There are no studies in the literature on the distribution of colorectal pathologies in Azerbaijan, we evaluated the prevalence and histopathologic features of neoplastic and non-neoplastic diseases in 289 colonoscopy ex-aminations performed in this cross-sectional study within 8 years.
💡
Conclusion & Impact:It has been found that there is a very significant reciprocal relationship between complaints and the rate of inflammatory diseases of the colon (odds ratio=10.59).
🔬Design:Research Article
📍Scope:2009-2017 Verileri
⚙️Variables:Domain Parameters

Abstract

Background and Aims: It is known that many of the colorectal diseases are related to age, gender, race, ethnicity and geographical position of peo-ple. There are no studies in the literature on the distribution of colorectal pathologies in Azerbaijan, we evaluated the prevalence and histopathologic features of neoplastic and non-neoplastic diseases in 289 colonoscopy ex-aminations performed in this cross-sectional study within 8 years. Mate-rials and Methods: We evaluated the colonoscopies and histopathologic results of our patients according to various indications in Oksigen, Hayat and Azerbaijan Medical University Training and Treatment clinics in Baku between 2009-2017. Results: A total of 289 cases underwent colonoscopy (89 males and 200 females, mean age 43.6±14.0). In 241 patients with lower gastrointestinal system complaints, colonoscopy was normal in 69 (28.6%). 23 patients (9.5%) had diverticulum, 12 had diverticulitis, and 4 patients (1.7%) had inflammatory bowel disease. In 50 patients (20.7%), unspecified colitis, in 4 (1.7%) angiodisplasia, in 4 (1.7%) melanosis and in 52 (21.6%) polyps were placed. Cancers were seen in 9 of the cases (3.7%). Clinical and endoscopic hemorrhoids were found in 86 patients (35.7%), anal fissure in 10 patients (4.1%), hemorrhoid fissure association in 15 patients (6.2%). Macroscopically no pathology was detected in 26 (54.2%) of 48 asymptom-atic cases. Unspecified colitis was detected in 2 of the cases (4.2%), polyp in 12 (25.0%) and asymptomatic hemorrhoid in 13 (27%). According to the type of histopathology, 5.5% of the polyps were inflammatory polyps, 30.6% were hyperplastic polyps, 55.6% were tubular adenomas, 5.5% were villous adenomas and 2.8% tubulo-villous adenoma. The tumors we identified as colon cancer were histopathologically adenocarcinoma. 40.0% of the polyps seen in asymptomatic cases were defined as hyperplastic polyps and 60.0% as tubular adenomas. We did not encounter any complications during colo-noscopic procedures. Conclusion: There was no correlation between the lower gastrointestinal complaints and the rate of polyps detected in the colo-noscopy (odds ratio=0.83, prevalence ratio=0.864). It has been found that there is a very significant reciprocal relationship between complaints and the rate of inflammatory diseases of the colon (odds ratio=10.59).

Özet

Giriş ve Amaç: Kolorektal hastalıklarının birçoğunun insanların yaşı, cinsi-yeti, ırkı, etnik kökeni ve coğrafi konumu ile ilgileşim gösterdiği bilinmek-tedir. Literatürde Azerbeycan’da kolorektal patolojilerin dağılımını irdeleyen herhangi bir çalışma bulunmadığından, biz bu kesitsel çalışmamızda 8 yıl içinde yaptığımız 289 kolonoskopi incelemesindeki neoplastik ve non ne-oplastik hastalıkların oranını ve histopatolojik özelliklerini değerlendirdik.Gereç ve Yöntem: 2009-2017 tarihleri arasında Bakü’de Oksigen, Hayat ve Azerbaycan Tıp Üniversitesi’nin Eğitim ve Tedavi kliniklerinde çeşitli en-dikasyonlara göre yaptığımız kolonoskopileri ve histopatolojik sonuçlarını değerlendirdik. Bulgular: Toplam 289 vakaya kolonoskopi uyguladık (89 erkek ve 200 kadın, yaş ortalaması 43.6±14.0). Alt gastrointestinal sistem şikayetleri ile baş vurmuş hastaların (hasta grubu; 241 vaka, 73 erkek ve 168 kadın, yaş ortalaması 42.4±14.3) 69’unda (%28.6) kolonoskopi sonucu normal bulunurken, 23’ünde (%9.5) divertikül, 12’sinde (%5) divertikülit, 4’ünde (%1.7) inflamatuvar barsak hastalığı, 50’sinde (%20.7) tanımlan-mamış kolit, 4’ünde (%1.7) anjiyodisplazi, 4’ünde (%1.7) melanozis koli, 52’sinde (%21.6) polip, 9’unda (%3.7) ise kanser görüldü. Hasta grubundaki vakaların 86’sında (%35.7) klinik ve endoskopik olarak hemoroit, 10’unda (%4.1) anal fissür, 15’inde (%6.2) hemoroitle fissür birlikteliği vardı. Kontrol amaçlı asemptomatik 48 vakadan (kontrol grubu,16 erkek ve 32 kadın, yaş ortalaması 49.6±10.6) oluşan gruptaki olguların 26’sında (%54.2) makros-kobik olarak hiç bir patoloji görülmezken, 2’sinde (%4.2) tanımlanmamış kolit, 12’sinde (%25) ise polip saptandı. Kontrol grubunda vakaların 13’ünde (%27) asemptomatik hemoroit görüldü. Histopatoloji tipine göre hasta gru-bundaki poliplerin %5.5’i inflamatuvar polip, %30.6’sı hiperplastik polip, %55.6’sı tübüler adenom, %5.5’i villöz adenom, %2.8’i ise tübülo-villöz adenom idi. Kolonoskopide kanser olarak tanımladığımız tümörler histopa-tolojik açıdan adenokarsinom yapısında idi. Kontrol grubundaki poliplerin %40’ı hiperplastik polip, %60’ı tübüler adenom olarak tanımlandı. Yapılan kolonoskopik işlemler sırasında komplikasyonla karşılaşmadık. Sonuç: Alt gastrointestinal şikayetler ve kolonoskopide saptanan polip oranı arasında ilişki tespit edilemezken (olasılık oranı=0.83; yaygınlık oranı=0.864), şika-yetler ve kalın barsağın iltihabi hastalıklarının oranı arasında çok belirgin bir karşılıklı ilişkinin mevcut olduğu tespit edildi (olasılık oranı=10.59).

🔖

Cite This Article

SÜLEYMAN, N. (2022). Prevalence and histopathological characteristics of colorectal neoplastic and nonneoplastic diseases in Azerbaijan. Endoskopi, Cilt: 26 - Sayı: 3, 78–83. https://ajindex.com/articles/501044

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (10)

  1. Alijev J, Mardanlı F, Guliyev F, et al. Epidemiolgical aspects of malignant neoplasms in Azerbaijan Republic in 2008-2013. Azerbaycan Onkoloji Jurnalı 2014;2:32-8.
  2. ASGE Technology Committee, Appalaneni V, Fanelli RD, et al. The role of endoscopy in patients with anorectal disorders. Gastrointest Endosc 2010;72:1117-23.
  3. Yücel Y, Aktümen A, Aydoğan T, et al. Alt gastrointestinal sistem endos-kopisi: 1800 olgunun retrospektif analizi ve kolorektal kanser sıklığının belirlenmesi. Endoskopi Gastrointestinal 2015;23:6-8.
  4. Montgomery EA, Voltaggio L. Gastrointestinal Traktüs Mukozası Biyop-silerinin Yorumu, Cilt 1: Nonneoplastik Nonneoplastik - Biyopsi Yo-rumları Serisi. Çeviren Prof. Dr. Funda Yılmaz Barbet, Nobel Tıp Kita-bevleri, 2014.
  5. Grjibovski AM, Ivanov SV. Cross-sectional studies in health sciences. Science and Healthcare 2015;2:5-18 (Rusça). Quigley MM, Fried M, Gwee Kok-Ann, et al. IBS: WGO PracticeGui-delines. World Gastroenterology Organization, 2015 September. http:// www.worldgastroenterology.org/guidelines/global-guidelines/irritab-le-bowel-syndrome-ibs Coşkun A, Kandemir A. Kolonoskopik polipektomi sonuçlarımızın ana-lizi. Endoskopi Gastrointestinal 2017;25:66-9.
  6. Ivashkin VT, Shelygin YA, Achkasov SI, et al. Diagnostics and treatment of diverticular disease of the colon: guidelines of the Russian gastroente-rological Association and Russian Association of Coloproctology. Ross Z Gastroenterol Gepatol Koloproktol 2016;26:65-80 (www.gastro-j.ru). Yakut M, Uysal E, Beşik G, et al. How do Turkish people perceive co-lonoscopy procedure? A Research on the factors effecting adaptation to colonoscopic preliminary diet: A clinical prospective study. Endoskopi Gastrointestinal 2009;17:69-71.
  7. Loffeld RJ, Liberov B, Dekkers PE. The yearly prevalence of findings in endoscopy of the lower part of the gastrointestinal tract. ISRN Gastroen-terology 2012;2012:527634. Yiğit T. Kolonoskopi deneylerimiz: Ardışık 983 hastanın irdelenmesi. Turk J Colorectal Dis 2007;17:154-9.
  8. Tamer A, Korkut E, Korkmaz U, Akcan Y. Alt gastrointestinal endos-kopi sonuçlarımız: Düzce bölgesi. The Medical Journal of Kocatepe 2005;6:29-31.
  9. Uçmak F, Tuncer ET, Ekin N, et al. Incidence and characteristics of colon polyps in Southeast Anatolian Region: A 5-year evaluation. Turk J Colorectal Dis 2016;2:21-6.
  10. Godil A, Chang A, Foliente R, et al. Colorectal polyp detection rates: A prospective comparison between 19’’ HD CRT monitor, 26’’ HD LCD monitor, and 42’’ HD plasma monitor and high definiti