Journals / Endoskopi Gastrointestinal / 2018 / Cilt: 26 Sayı: 3

PREVALENCE AND HISTOPATHOLOGICAL CHARACTERISTICS OF COLORECTAL NEOPLASTIC AND NONNEOPLASTIC DISEASES IN AZERBAIJAN

AZERBAYCAN’DA KOLOREKTAL NEOPLASTİK VE NONNEOPLASTİK HASTALIKLARIN ORANI VE HİSTOPATOLOJİK ÖZELLİKLERİ

Nigar Süleyman(Azerbaijan Medical University, Baku)0000-0002-7803-1953
Pages
78–83
Publication Date
2018-12-28
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⚡ TL;DR(Too Long; Didn't Read)

It has been found that there is a very significant reciprocal relationship between complaints and the rate of inflammatory diseases of the colon (odds ratio=10.59).

📌 3 Key Takeaways

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Objective & Hypothesis:Background and Aims : It is known that many of the colorectal diseases are related to age, gender, race, ethnicity and geographical position of people.
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Key Findings & Data:There are no studies in the literature on the distribution of colorectal pathologies in Azerbaijan, we evaluated the prevalence and histopathologic features of neoplastic and non-neoplastic diseases in 289 colonoscopy examinations performed in this cross-sectional study within 8 years.
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Conclusion & Impact:It has been found that there is a very significant reciprocal relationship between complaints and the rate of inflammatory diseases of the colon (odds ratio=10.59).
🔬Design:Araştırma Makalesi
📍Scope:2009-2017 Verileri
⚙️Variables:Azerbaycan · kolonskopi · kolorektal neoplazmalar

Abstract

Background and Aims : It is known that many of the colorectal diseases are related to age, gender, race, ethnicity and geographical position of people. There are no studies in the literature on the distribution of colorectal pathologies in Azerbaijan, we evaluated the prevalence and histopathologic features of neoplastic and non-neoplastic diseases in 289 colonoscopy examinations performed in this cross-sectional study within 8 years. Materials and Methods : We evaluated the colonoscopies and histopathologic results of our patients according to various indications in Oksigen, Hayat and Azerbaijan Medical University Training and Treatment clinics in Baku between 2009-2017. Result s : A total of 289 cases underwent colonoscopy (89 males and 200 females, mean age 43.6±14.0). In 241 patients with lower gastrointestinal system complaints, colonoscopy was normal in 69 (28.6%). 23 patients (9.5%) had diverticulum, 12 had diverticulitis, and 4 patients (1.7%) had inflammatory bowel disease. In 50 patients (20.7%), unspecified colitis, in 4 (1.7%) angiodisplasia, in 4 (1.7%) melanosis and in 52 (21.6%) polyps were placed. Cancers were seen in 9 of the cases (3.7%). Clinical and endoscopic hemorrhoids were found in 86 patients (35.7%), anal fissure in 10 patients (4.1%), hemorrhoid fissure association in 15 patients (6.2%). Macroscopically no pathology was detected in 26 (54.2%) of 48 asymptomatic cases. Unspecified colitis was detected in 2 of the cases (4.2%), polyp in 12 (25.0%) and asymptomatic hemorrhoid in 13 (27%). According to the type of histopathology, 5.5% of the polyps were inflammatory polyps, 30.6% were hyperplastic polyps, 55.6% were tubular adenomas, 5.5% were villous adenomas and 2.8% tubulo- villous adenoma. The tumors we identified as colon cancer were histopathologically adenocarcinoma. 40.0% of the polyps seen in asymptomatic cases were defined as hyperplastic polyps and 60.0% as tubular adenomas. We did not encounter any complications during colonoscopic procedures. Conclusion: There was no correlation between the lower gastrointestinal complaints and the rate of polyps detected in the colonoscopy (odds ratio=0.83, prevalence ratio=0.864). It has been found that there is a very significant reciprocal relationship between complaints and the rate of inflammatory diseases of the colon (odds ratio=10.59).

Özet

Giriş ve Amaç: Kolorektal hastalıklarının birçoğunun insanların yaşı, cinsiyeti, ırkı, etnik kökeni ve coğrafi konumu ile ilgileşim gösterdiği bilinmektedir. Literatürde Azerbeycan’da kolorektal patolojilerin dağılımını irdeleyen herhangi bir çalışma bulunmadığından, biz bu kesitsel çalışmamızda 8 yıl içinde yaptığımız 289 kolonoskopi incelemesindeki neoplastik ve non neoplastik hastalıkların oranını ve histopatolojik özelliklerini değerlendirdik. Gereç ve Yöntem: 2009-2017 tarihleri arasında Bakü’de Oksigen, Hayat ve Azerbaycan Tıp Üniversitesi’nin Eğitim ve Tedavi kliniklerinde çeşitli endikasyonlara göre yaptığımız kolonoskopileri ve histopatolojik sonuçlarını değerlendirdik. Bulgular: Toplam 289 vakaya kolonoskopi uyguladık (89 erkek ve 200 kadın, yaş ortalaması 43.6±14.0). Alt gastrointestinal sistem şikayetleri ile baş vurmuş hastaların (hasta grubu; 241 vaka, 73 erkek ve 168 kadın, yaş ortalaması 42.4±14.3) 69’unda (%28.6) kolonoskopi sonucu normal bulunurken, 23’ünde (%9.5) divertikül, 12’sinde (%5) divertikülit, 4’ünde (%1.7) inflamatuvar barsak hastalığı, 50’sinde (%20.7) tanımlanmamış kolit, 4’ünde (%1.7) anjiyodisplazi, 4’ünde (%1.7) melanozis koli, 52’sinde (%21.6) polip, 9’unda (%3.7) ise kanser görüldü. Hasta grubundaki vakaların 86’sında (%35.7) klinik ve endoskopik olarak hemoroit, 10’unda (%4.1) anal fissür, 15’inde (%6.2) hemoroitle fissür birlikteliği vardı. Kontrol amaçlı asemptomatik 48 vakadan (kontrol grubu,16 erkek ve 32 kadın, yaş ortalaması 49.6±10.6) oluşan gruptaki olguların 26’sında (%54.2) makroskobik olarak hiç bir patoloji görülmezken, 2’sinde (%4.2) tanımlanmamış kolit, 12’sinde (%25) ise polip saptandı. Kontrol grubunda vakaların 13’ünde (%27) asemptomatik hemoroit görüldü. Histopatoloji tipine göre hasta grubundaki poliplerin %5.5’i inflamatuvar polip, %30.6’sı hiperplastik polip, %55.6’sı tübüler adenom, %5.5’i villöz adenom, %2.8’i ise tübülo-villöz adenom idi. Kolonoskopide kanser olarak tanımladığımız tümörler histopatolojik açıdan adenokarsinom yapısında idi. Kontrol grubundaki poliplerin %40’ı hiperplastik polip, %60’ı tübüler adenom olarak tanımlandı. Yapılan kolonoskopik işlemler sırasında komplikasyonla karşılaşmadık. Sonuç : Alt gastrointestinal şikayetler ve kolonoskopide saptanan polip oranı arasında ilişki tespit edilemezken (olasılık oranı=0.83; yaygınlık oranı=0.864), şikayetler ve kalın barsağın iltihabi hastalıklarının oranı arasında çok belirgin bir karşılıklı ilişkinin mevcut olduğu tespit edildi (olasılık oranı=10.59).

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Cite This Article

Süleyman, N. (2018). PREVALENCE AND HISTOPATHOLOGICAL CHARACTERISTICS OF COLORECTAL NEOPLASTIC AND NONNEOPLASTIC DISEASES IN AZERBAIJAN. Endoskopi Gastrointestinal, Cilt: 26 Sayı: 3, 78–83. https://doi.org/10.17940/endoskopi.475246

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