Journals / ENTcase / 2021 / Cilt: 7 - Sayı: 2

LOW AND SINGLE DOSE METHYLPREDNISOLONE THERAPY IN THE TREATMENT OF JUVENILE RECURRENT PAROTITIS

JUVENİL REKÜRREN PAROTİT TEDAVİSİNDE DÜŞÜK VE TEK DOZ METİLPREDNİZOLON UYGULAMASI

Journal
ENTcase
Pages
64–69
Publication Date
2022-10-12
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Since SCE or CSCE treatment options are not widespread and the application is difficult, low dose single iv corticosteroid administration may be recommended, especially in patients who do not respond to conservative treatments.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Juvenile recurrent parotitis (JRP) is a recurrent inflammation of the parotid gland of unknown etiology that occurs in childhood.
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Key Findings & Data:A 13-year-old girl presented with episodes of painful swelling and redness in the left parotid gland 5 times in the last 2 years.
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Conclusion & Impact:Since SCE or CSCE treatment options are not widespread and the application is difficult, low dose single iv corticosteroid administration may be recommended, especially in patients who do not respond to conservative treatments.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Juvenile recurrent parotitis (JRP) is a recurrent inflammation of the parotid gland of unknown etiology that occurs in childhood. The most studied and effective treatment option in the literature is stenon canal endoscopy (SCE) and irrigation of the canal with corticosteroid solution (CSCE). In this case report, the effectiveness of low and single-dose methylprednisolone treatment was discussed. A 13-year-old girl presented with episodes of painful swelling and redness in the left parotid gland 5 times in the last 2 years. Physical examination, patient history, laboratory and radiological examinations demonstrated the diagnosis of JRP. The patient was given a low single dose of 0.5 mg/kg methylprednisolone with pantoprazole (1 mg/kg, single dose, iv) intravenously. The patient stated that there was no need for additional medication in her control visit after one week. Since SCE or CSCE treatment options are not widespread and the application is difficult, low dose single iv corticosteroid administration may be recommended, especially in patients who do not respond to conservative treatments.

Özet

Juvenil rekürren parotit (JRP), parotis bezinin, çocukluk çağında ortaya çıkan, tekrarlayıcı, etyolojisi belirsiz inflamasyonudur. Literatürde en çok incelenmiş ve etkili tedavi seçeneği stenon kanalı endoskopisi (SKE) ile birlikte kanalın kortikosteroid solusyonu ile irrigasyonudur (KSKE). Bu olgu sunumunda düşük ve tek doz metilprednizolon tedavisinin etkinliği tartışılmıştır. Onüç yaşında kız hasta, son 2 yıl içerisinde 5 defa sol parotis bezde ağrılı şişlik, kızarıklık atakları nedeniyle başvurdu. Fizik muayene bulguları, hasta öyküsü, laboratuar ve radyolojik tetkikleri JRP ile uyumlu olarak bulundu. Hastada 0.5 mg/kg tek doz metilprednizolon, pantoprazol (1 mg/kg, tek doz, iv) ile birlikte tek doz intravenöz (iv) olarak verildi. Hasta, bir hafta sonraki kontrolünde ek ilaç gereksinimi olmadığı bildirdi. SKE ya da KSKE tedavi imkanı yaygın olmaması ve uygulama güçlüğü nedeni ile düşük dozda tek iv kortikosteroid uygulaması özellikle konservatif tedavilere yanıt alınamayan hastalarda tercih önerilebilir.

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Cite This Article

ŞİMŞEK, S., İŞLEK, A. (2022). LOW AND SINGLE DOSE METHYLPREDNISOLONE THERAPY IN THE TREATMENT OF JUVENILE RECURRENT PAROTITIS. ENTcase, Cilt: 7 - Sayı: 2, 64–69. https://ajindex.com/articles/499855

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References (11)

  1. Schneider H, et al. Juvenile recurrent parotitis: a retrospective comparison of sialendoscopy versus conservative therapy. Laryngoscope. 2014 Feb;124(2):451-5. doi: 10.1002/lary.24291. Epub 2013 Sep 19. PMID: 23818258
  2. Jabbour N, et al. Sialendoscopy in children. Int J Pediatr Otorhinolaryngol. 2010 Apr;74(4):347-50. doi: 10.1016/j.ijporl.2009.12.013. Epub 2010 Feb 8. PMID: 20116866
  3. Ramakrishna J, et al. Sialendoscopy for the management of juvenile recurrent parotitis: a systematic review and meta-analysis. Laryngoscope. 2015 Jun;125(6):1472-9. doi: 10.1002/lary.25029. Epub 2014 Nov 13. PMID: 25393103
  4. Gellrich D,et al. Salivary Gland Disorders in Children and Adolescents: A 15-year Experience. Int Arch Otorhinolaryngol. 2020 Jan;24(1):e31-e37. doi: 10.1055/s-0039-1697993. Epub 2020 Jan 9. PMID: 31929831; PMCID: PMC6952288
  5. Garavello W, et al. Juvenile recurrent parotitis: A systematic review of treatment studies. Int J Pediatr Otorhinolaryngol. 2018 Sep;112:151-157. doi: 10.1016/j.ijporl.2018.07.002. Epub 2018 Jul 4. PMID: 30055724
  6. Tucci FM, et al. Juvenile recurrent parotitis: Diagnostic and therapeutic effectiveness of sialography. Retrospective study on 110 children. Int J Pediatr Otorhinolaryngol. 2019 Sep;124:179-184. doi: 10.1016/j.ijporl.2019.06.007. Epub 2019 Jun 7. PMID: 31202035
  7. Xie LS, et al. Function of the parotid gland in juvenile recurrent parotitis: a case series. Br J Oral Maxillofac Surg. 2016 Apr;54(3):270-4. doi: 10.1016/j.bjoms.2016.01.017. Epub 2016 Feb 3. PMID: 26852271
  8. Schwarz Y, Bezdjian A, Daniel SJ. Sialendoscopy in treating pediatric salivary gland disorders: a systematic review. Eur Arch Otorhinolaryngol. 2018 Feb;275(2):347-356. doi: 10.1007/s00405-017-4830-2. Epub 2017 Dec 4. PMID: 29204918
  9. Berlucchi M, et al. Sialoendoscopy for treatment of juvenile recurrent parotitis: The Brescia experience. Int J Pediatr Otorhinolaryngol. 2018 Feb;105:163-166. doi: 10.1016/j.ijporl.2017.12.024. Epub 2017 Dec 26. PMID: 29447807
  10. Singh PP, Goyal M, Goyal A. Sialendoscopic Approach in Management of Juvenile Recurrent Parotitis. Indian J Otolaryngol Head Neck Surg. 2017 Dec;69(4):453-458. doi: 10.1007/s12070-017-1223-1. Epub 2017 Oct 16. PMID: 29238673; PMCID: PMC5714912
  11. Wang S, et al. Gland atrophy following retrograde injection of methyl violet as a treatment in chronic obstructive parotitis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1998 Mar;85(3):276-81. doi: 10.1016/s1079-2104(98)90008-7.