AI Summary & Key Takeaways
AI InsightIn our case we have made the observation that during growth and sexual maturation,zinc deficiency decreases growth hormone production, insulin like growth factor-1(IGF-1) and testosteron levels and bone mineral dansity(BMD).
📌 3 Key Takeaways
Abstract
Prasad syndrome is characterized by geophagia, iron deficiency anemia, growth retardation, hypogonadism and zinc deficiency. This syndrome has been observed in both sexes in Turkey for several decades. We decided to evaluate the Hypothalamic-hypophysial-gonadal axis of a 15 year old male patient whom we accepted as prasad syndrome. In our case we have made the observation that during growth and sexual maturation,zinc deficiency decreases growth hormone production, insulin like growth factor-1(IGF-1) and testosteron levels and bone mineral dansity(BMD).
Özet
Prasad sendromu demir eksikliği anemisi, jeofagi, büyüme geriliği, hipogonadizm ve çinko eksikliği ile karakterizedir. Türkiye'de yıllardır her iki sekste gözükmektedir. Kliniğimize başvuran prasad sendromu tanısı koyduğumuz 15 yaşındaki erkek vakanın, hipothalamo hipofizer gonadal aksını inceledik.Vakada,çinko eksikliği growth hormon yapımını, insulin like growth faktör-1 (IGF-1) düzeyini azalttığını,kemik mineral dansitesi (BMD)ve testosteron seviyesini düşürdüğünü tespit ettik.