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Journals / Ege Tıp Dergisi / 2021 / Cilt: 60 - Sayı: Supplement

Microbiome and microbiota

Mikrobiyom ve mikrobiyota

Behice Kurtaran
Pages
88–93
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

There are studies showing a relationship between dysbiosis and cardiovascular disease, obesity, type 2 diabetes, non-alcoholic fatty liver disease (NAFLD) and certain types of cancer.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Microbiome and microbiota are commonly used interchangeably and are the name given to the community of commensal, symbiotic and pathogenic microorganisms found in the human body.
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Key Findings & Data:If microbiota diversity decreases, changes or deteriorates, which is called dysbiosis, immune dysregulation leading to allergy and inflammation occurs.
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Conclusion & Impact:There are studies showing a relationship between dysbiosis and cardiovascular disease, obesity, type 2 diabetes, non-alcoholic fatty liver disease (NAFLD) and certain types of cancer.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Microbiome and microbiota are commonly used interchangeably and are the name given to the community of commensal, symbiotic and pathogenic microorganisms found in the human body. Microorganisms in the human body are localized in the gastrointestinal tract, oropharyngeal area, skin, airways, urogenital system, blood and eyes. There are protective, metabolic and structural effects of gastrointestinal microbiome. Intestinal microbiota balance is achieved by maintaining the equilibrium of the microbial composition that provides immune regulation, i.e. symbiosis. If microbiota diversity decreases, changes or deteriorates, which is called dysbiosis, immune dysregulation leading to allergy and inflammation occurs. In other words, gastrointestinal microbiota has great clinical importance in the maintenance of human health. There are studies showing a relationship between dysbiosis and cardiovascular disease, obesity, type 2 diabetes, non-alcoholic fatty liver disease (NAFLD) and certain types of cancer.

Özet

Mikrobiyom ve mikrobiyota sıklıkla birbirlerinin yerine kullanılan ve insan vücudunda bulunan kommensal, simbiyotik ve patojenik mikroorganizmaların topluluğuna verilen isimdir. İnsan vücudunda mikroorganizmalar gastrointestinal sistem, orofaringeal alan, deri, hava yolları, ürogenital sistem, kan ve gözlerde lokalize olmuştur. Gastrointestinal mikrobiyomun koruyucu, metabolik ve yapısal etkileri söz konusudur. İntestinal mikrobiyota dengesi, immün regülasyonu sağlayan mikrobiyal kompozisyonun dengede kalması ile yani simbiyoz ile sağlanır. Eğer mikrobiyota çeşitliliğinde azalma, değişiklik ya da bozulma olursa –ki bu disbiyoz olarak adlandırılır- alerji ve inflamasyonla giden immün disregülasyon meydana gelir. Yani insan sağlığının idamesinde gastrointestinal mikrobiyotanın klinik önemi büyüktür. Kardiyovasküler hastalık, obesite, tip 2 diyabet, non-alkolik yağlı karaciğer hastalığı (NAFLD) ve bazı kanser tipleri ile disbiyoz arasında ilişki olduğunu gösteren çalışmalar mevcuttur.

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Cite This Article

Kurtaran, B. (2022). Microbiome and microbiota. Ege Tıp Dergisi, Cilt: 60 - Sayı: Supplement, 88–93. https://ajindex.com/articles/496036

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