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Journals / Düzce Üniversitesi Bilim ve Teknoloji Dergisi / 2021 / Cilt: 9 - Sayı: 3

Human Serum Albumin Nanoparticles/surfactant Polymer Based Sensor for the Non-enzymatic Electroanalysis of Methyl Parathion

İnsan Serum Albümin Nanopartikül/surfaktant Polimer Temelli Sensör ile Metil Paratiyonun Enzimsiz Elektroanalizi

Gülçin BOLAT
Pages
482–499
Publication Date
2022-10-12
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The HSA NP/p(CTAB) based electrochemical sensor developed for MP detection with a simple preparation strategy and did not require the use of enzymes and has the potential to be applied in environmental protection and food safety monitoring processes.

📌 3 Key Takeaways

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Objective & Hypothesis:In this study, human serum albumin nanoparticles (HSA NP) and electrodeposited surfactant polycetyltrimethyl ammonium bromide p(CTAB) film coated graphite electrodes (PGE) were utilized as an electrochemical sensor for the sensitive and selective detection of a hazardous environmental pollutant, methyl parathion (MP).
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Key Findings & Data:The linear working range obtained for the MP was determined as 0.01-0.1 µM and the detection limit as 6 nM by differential pulse voltammetry (DPV) technique.
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Conclusion & Impact:The HSA NP/p(CTAB) based electrochemical sensor developed for MP detection with a simple preparation strategy and did not require the use of enzymes and has the potential to be applied in environmental protection and food safety monitoring processes.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Organofosforlu pesitisit · Albumin nanopartikül · Surfaktant polimer

Abstract

In this study, human serum albumin nanoparticles (HSA NP) and electrodeposited surfactant polycetyltrimethyl ammonium bromide p(CTAB) film coated graphite electrodes (PGE) were utilized as an electrochemical sensor for the sensitive and selective detection of a hazardous environmental pollutant, methyl parathion (MP). The fabricated HSA NP/p(CTAB)/PGE was characterized microscopically and electrochemically. The linear working range obtained for the MP was determined as 0.01-0.1 µM and the detection limit as 6 nM by differential pulse voltammetry (DPV) technique. The HSA NP/p(CTAB) based electrochemical sensor developed for MP detection with a simple preparation strategy and did not require the use of enzymes and has the potential to be applied in environmental protection and food safety monitoring processes.

Özet

Bu çalışmada, insan serum albümin nanopartiküller (HSA NP) ve elektrobiriktirilmiş yüzey aktif polisetiltrimetil amonyum bromür p(CTAB) film kaplı grafit elektrotlar (PGE) tehlikeli bir çevresel kirletici olan metil paratiyonun (MP) hassas ve seçici tespiti için elektrokimyasal sensör olarak kullanıldı. Elde edilen HSA NP/p(CTAB)/PGE mikroskopik ve elektrokimyasal olarak karakterize edildi. Diferansiyel puls voltametri (DPV) tekniği ile MP için elde edilen doğrusal çalışma aralığı 0,01-0,1 µM ve gözlenebilme sınırı ise 6 nM olarak tespit edildi. MP tespiti için geliştirilen enzim kullanımı gerektirmeyen ve basit hazırlama stratejisine sahip HSA NP/p(CTAB) tabanlı elektrokimyasal sensör, çevre koruma ve gıda güvenliği açısından izleme sürecini de basitleştirme potansiyeline sahiptir.

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Cite This Article

BOLAT, G. (2022). Human Serum Albumin Nanoparticles/surfactant Polymer Based Sensor for the Non-enzymatic Electroanalysis of Methyl Parathion. Düzce Üniversitesi Bilim ve Teknoloji Dergisi, Cilt: 9 - Sayı: 3, 482–499. https://ajindex.com/articles/494011

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References (10)

  1. M. Govindasamy, S. Sakthinathan, S. M. Chen, T. W. Chiu, A. Sathiyan, ve J. P. Merlin, “Reduced Graphene Oxide Supported Cobalt Bipyridyl Complex for Sensitive Detection of Methyl Parathion in Fruits and Vegetables,” Electroanalysis, c. 29, s. 8, ss. 1950–1960, 2017
  2. D. M. Maxwell, K. M. Brecht, I. Koplovitz, ve R. E. Sweeney, “Acetylcholinesterase inhibition: Does it explain the toxicity of organophosphorus compounds?,” Arch. Toxicol., c. 80, s. 11, ss. 756–760, 2006. [3] “WHO Recommended Classification of Pesticides by Hazard and Guidelines to he WHO recommended classification of pesticides by hazard and guidelines to classification, 2009 edition - International Program on Chemical Safety, World Health Organization [Erişim: 30-Haz-2020]
  3. G. M. Benke, K. L. Cheever, F. E. Mirer, ve S. D. Murphy, “Comparative toxicity, anticholinesterase action and metabolism of methyl parathion and parathion in sunfish and mice,” Toxicol. Appl. Pharmacol., c. 28, s. 1, ss. 97–109, 1974
  4. EC Drinking Water Directive 98/83/EC European Commission (1998)
  5. C. Liu, B. Guo, ve J. Xue, “Analytical Methods for Pesticides and Herbicides,” Water Environ. Res., c. 90, s. 10, ss. 1323–1347, 2018
  6. J. Chen, W. T. Zhang, Y. Shu, X. H. Ma, and X. Y. Cao, “Detection of Organophosphorus Pesticide Residues in Leaf Lettuce and Cucumber Through Molecularly Imprinted Solid-Phase Extraction Coupled to Gas Chromatography,” Food Anal. Methods, c. 10, s. 10, ss. 3452–3461, 2017
  7. Y. Shin, J. Lee, J. Lee, J. Lee, E. Kim, K.H. Liu, H. S. Lee, ve J. H. Kim, “Validation of a Multiresidue Analysis Method for 379 Pesticides in Human Serum Using Liquid Chromatography-Tandem Mass Spectrometry,” J. Agric. Food Chem., c. 66, s. 13, ss. 3550–3560, 2018
  8. A. V. B. Reddy, Z. Yusop, J. Jaafar, A. B. Aris, Z. A. Majid, K. Umar, ve J. Talib, “Simultaneous determination of three organophosphorus pesticides in different food commodities by gas chromatography with mass spectrometry,” J. Sep. Sci., c. 39, s. 12, ss. 2276–2283, 2016
  9. A. Menezes Filho, F. N. dos Santos, ve P. A. de Paula Pereira, “Development, validation and application of a methodology based on solid-phase micro extraction followed by gas chromatography coupled to mass spectrometry (SPME/GC-MS) for the determination of pesticide residues in mangoes,” Talanta, c. 81, s. 1–2, ss. 346–354, 2010
  10. Y. Zeng, D. Yu, Y. Yu, T. Zhou, ve G. Shi, “Differential pulse voltammetric determination of methyl parathion based on mult